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S100A12 Protein (His tag)

S100A12 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 97 % by SDS-PAGE. Active
Catalog No. ABIN7533717
  • Target See all S100A12 Proteins
    S100A12 (S100 Calcium Binding Protein A12 (S100A12))
    Protein Type
    Recombinant
    Biological Activity
    Active
    Origin
    • 11
    • 2
    • 2
    • 2
    Human
    Source
    • 12
    • 3
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This S100A12 protein is labelled with His tag.
    Purpose
    Active Recombinant Human S100-A12 Protein
    Sequence
    MTKLEEHLEG IVNIFHQYSV RKGHFDTLSK GELKQLLTKE LANTIKNIKD KAVIDEIFQG LDANQDEQVD FQEFISLVAI ALKAAHYHTH KE
    Specificity
    Met1-Glu92
    Purity
    > 97 % by SDS-PAGE.
    Endotoxin Level
    < 0.1 EU/μg of the protein by LAL method.
    Biological Activity Comment
    Measured by its binding ability in a functional ELISA. Immobilized Human S100A12 at 2 μg/mL (100 μL/well) can bind recombinant Human AGER/RAGE with a linear range of 0.1-27.25 ng/mL.
    Top Product
    Discover our top product S100A12 Protein
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.877 mg/mL
    Buffer
    Supplied in PBS, 25 % glycerol, pH 7.4
    Storage
    -80 °C
    Storage Comment
    This product is stable at ≤ -70° C for up to 1 year from the date of receipt.
    For optimal storage, aliquot into smaller quantities after centrifugation and store at recommended temperature.
  • Target
    S100A12 (S100 Calcium Binding Protein A12 (S100A12))
    Alternative Name
    S100-A12 (S100A12 Products)
    Synonyms
    CAAF1 Protein, CAGC Protein, CGRP Protein, ENRAGE Protein, MRP-6 Protein, MRP6 Protein, p6 Protein, CO-AG Protein, EN-RAGE Protein, S100 calcium binding protein A12 Protein, protein S100-A12 Protein, S100A12 Protein, LOC101103771 Protein
    Background

    Description: The protein is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 proteins include at least 13 members which are located as a cluster on chromosome 1q21. This protein is proposed to be involved in specific calcium-dependent signal transduction pathways and its regulatory effect on cytoskeletal components may modulate various neutrophil activities. The protein includes an antimicrobial peptide which has antibacterial activity.

    Name: S100A12,CAAF1,CAGC,CGRP,ENRAGE,MRP-6,MRP6,p6

    Gene ID
    6283
    UniProt
    P80511
    Pathways
    Toll-Like Receptors Cascades, S100 Proteins
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