SULT1A1 Protein (His tag)

Catalog No. ABIN7533780

Product Details

Target: SULT1A1 (Sulfotransferase Family, Cytosolic, 1A, Phenol-Preferring, Member 1 (SULT1A1))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This SULT1A1 protein is labelled with His tag.

Purpose: Recombinant Human Sulfotransferase 1A1/SULT1A1 Protein

Sequence: MELIQDTSRP PLEYVKGVPL IKYFAEALGP LQSFQARPDD LLISTYPKSG TTWVSQILDM IYQGGDLEKC HRAPIFMRVP FLEFKAPGIP SGMETLKDTP APRLLKTHLP LALLPQTLLD QKVKVVYVAR NAKDVAVSYY HFYHMAKVHP EPGTWDSFLE KFMVGEVSYG SWYQHVQEWW ELSRTHPVLY LFYEDMKENP KREIQKILEF VGRSLPEETV DFVVQHTSFK EMKKNPMTNY TTVPQEFMDH SISPFMRKGM AGDWKTTFTV AQNERFDADY AEKMAGCSLS FRSEL

Specificity: Met1-Leu295

Purity: > 95 % by SDS-PAGE.

Sterility: 0.22 μm filtered

Endotoxin Level: < 0.01 EU/μg of the protein by LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.

Buffer: Lyophilized from a 0.22 μm filtered solution of 20 mM Tris, 150 mM NaCl, pH 8.0.

Storage: -20 °C,-80 °C

Storage Comment: Store the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.

Target Details

Target: SULT1A1 (Sulfotransferase Family, Cytosolic, 1A, Phenol-Preferring, Member 1 (SULT1A1))

Alternative Name: Sulfotransferase 1A1/SULT1A1 (SULT1A1 Products)

Synonyms: HAST1/HAST2 Protein, P-PST Protein, PST Protein, ST1A1 Protein, ST1A3 Protein, STP Protein, STP1 Protein, TSPST1 Protein, AI266890 Protein, Stp Protein, Stp1 Protein, ASTIV Protein, Mx-ST Protein, PST-1 Protein, St1a1 Protein, Stm Protein, Sult1a3 Protein, pst Protein, st1a3 Protein, stp Protein, stp1 Protein, tspst1 Protein, cSULT1A1 Protein, SULT1A2 Protein, SULT1A1 Protein, SIAT8-D Protein, ST8SiaIV Protein, Siat8d Protein, PST1 Protein, SIAT8D Protein, ST8SIA-IV Protein, sulfotransferase family 1A member 1 Protein, sulfotransferase family 1A, phenol-preferring, member 1 Protein, sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 Protein, sulfotransferase family 1A member 1 S homeolog Protein, sulfotransferase 1A1 Protein, ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 Protein, SULT1A1 Protein, Sult1a1 Protein, sult1a1 Protein, sult1a1.S Protein, LOC704658 Protein, LOC709318 Protein, St8sia4 Protein, ST8SIA4 Protein, LOC100064221 Protein

Background:

Description: Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds.Particularly SULT1A1 (Sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1), a member of the sulfotransferase 1 subfamily, which is a major pathway for drug metabolism in humans. Statistically significant associations were observed between the SULT1A1 genotype (Arg213His) and age, obesity and certain neoplasias (mammary, pulmonary, esophageal and urothelial cancer). Furthermore, the polymorphism of the SULT1A1 may be closely associated with breast cancer.

Name: SULT1A1,HAST1/HAST2,P-PST,PST,ST1A1,ST1A3,STP,STP1,TSPST1

Gene ID: 6817

UniProt: P50225