TGFA Protein
Quick Overview for TGFA Protein (ABIN7536426)
Target
See all TGFA ProteinsProtein Type
Origin
Source
Purity
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Purpose
- Recombinant Human TGF-alpha/TGFA Protein
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Sequence
- VVSHFNDCPD SHTQFCFHGT CRFLVQEDKP ACVCHSGYVG ARCEHADLLA
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Specificity
- Val40-Ala89
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Sterility
- 0.22 μm filtered
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Endotoxin Level
- <1EU/μg
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Transforming Growth Factor, alpha (TGFA) (AA 40-89) protein (Fc Tag)
TGFA Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Transforming Growth Factor, alpha (TGFA) (AA 39-88) protein (Fc Tag)TGFA Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Transforming Growth Factor, alpha (TGFA) (AA 40-89) protein (His tag)TGFA Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Transforming Growth Factor, alpha (TGFA) (AA 1-159) protein (GST tag)TGFA Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
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Concentration
- 0.3 mg/mL
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Buffer
- Lyophilized from a 0.22 μm filtered solution of 50 mM Tris,100 mM NaCl, pH 8.0
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Storage
- -20 °C,-80 °C
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Storage Comment
- Store the lyophilized protein at -20°C to -80°C for 12 months.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
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- TGFA (Transforming Growth Factor, alpha (TGFA))
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Alternative Name
- TGF-alpha/TGFA
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Background
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Description: The miR-137 served as a tumor suppressor in non-small cell lung cancer (NSCLC) and its suppressive effect is mediated by repressing TGFA expression. TGFA gene expression was significantly higher in tumor tissues compared to adjacent normal tissue and high TGFA gene expression strongly correlated with poor survival in patients with lung adenocarcinoma, and miR-374a suppresses lung adenocarcinoma cell proliferation and invasion via targeting TGFA gene expression. Transforming growth factor alpha (TGFA) is a well-characterized mammalian growth factor that might contribute to the development of Cleft lip and palate (CL/P).
Name: TFGA,TGF-alpha
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Gene ID
- 7039
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UniProt
- P01135-1
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Pathways
- NF-kappaB Signaling, RTK Signaling, EGFR Signaling Pathway
Target
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