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Vasn Protein (His tag)

Vasn Origin: Human Host: HEK-293 Cells Recombinant > 95 % by SDS-PAGE.
Catalog No. ABIN7535366
  • Target See all Vasn Proteins
    Vasn (Vasorin (Vasn))
    Protein Type
    Recombinant
    Origin
    • 8
    • 1
    Human
    Source
    • 2
    • 2
    • 2
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This Vasn protein is labelled with His tag.
    Purpose
    Recombinant Human Vasorin/SLIT-like 2/VASN Protein
    Sequence
    MCSRVPLLLP LLLLLALGPG VQGCPSGCQC SQPQTVFCTA RQGTTVPRDV PPDTVGLYVF ENGITMLDAG SFAGLPGLQL LDLSQNQIAS LPSGVFQPLA NLSNLDLTAN RLHEITNETF RGLRRLERLY LGKNRIRHIQ PGAFDTLDRL LELKLQDNEL RALPPLRLPR LLLLDLSHNS LLALEPGILD TANVEALRLA GLGLQQLDEG LFSRLRNLHD LDVSDNQLER VPPVIRGLRG LTRLRLAGNT RIAQLRPEDL AGLAALQELD VSNLSLQALP GDLSGLFPRL RLLAAARNPF NCVCPLSWFG PWVRESHVTL ASPEETRCHF PPKNAGRLLL ELDYADFGCP ATTTTATVPT TRPVVREPTA LSSSLAPTWL SPTEPATEAP SPPSTAPPTV GPVPQPQDCP PSTCLNGGTC HLGTRHHLAC LCPEGFTGLY CESQMGQGTR PSPTPVTPRP PRSLTLGIEP VSPTSLRVGL QRYLQGSSVQ LRSLRLTYRN LSGPDKRLVT LRLPASLAEY TVTQLRPNAT YSVCVMPLGP GRVPEGEEAC GEAHTPPAVH SNHAPVTQAR EGNLP
    Specificity
    Met1-Pro575
    Purity
    > 95 % by SDS-PAGE.
    Sterility
    0.22 μm filtered
    Endotoxin Level
    <1EU/μg
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  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
    Buffer
    Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Store the lyophilized protein at -20°C to -80°C for long term.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
  • Target
    Vasn (Vasorin (Vasn))
    Alternative Name
    Vasorin/SLIT-like 2/VASN (Vasn Products)
    Synonyms
    MGC88956 Protein, SLITL2 Protein, 2610528G05Rik Protein, Atia Protein, Slitl2 Protein, vasorin Protein, vasn Protein, VASN Protein, CpipJ_CPIJ018010 Protein, CpipJ_CPIJ019764 Protein, Vasn Protein
    Background

    Description: Vasorin (VASN),a single-pass type I membrane protein, is also known as protein slit-like 2 and SLITL2, which contains one EGF-like domain, ten LRR (leucine-rich) repeats, one LRRCT domain and one LRRNT domain.Vasorin is predominantly expressed in vascular smooth muscle cells, and that its expression is developmentally regulated. vasorin It directly binds to transforming growth factor (TGF)-β and attenuates TGF-β signaling in vitro. This suggests that down-regulation of vasorin expression contributes to neointimal formation after vascular injury and that vasorin modulates cellular responses to pathological stimuli in the vessel wall.

    Name: VASN,SLITL2,vasorin

    Gene ID
    114990
    UniProt
    Q6EMK4
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