MUC1 Protein
Quick Overview for MUC1 Protein (ABIN7849659)
Target
See all MUC1 ProteinsProtein Type
Origin
Source
Application
Purity
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Purpose
- Native Human CA153 Protein
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Mucin 1 (MUC1) (AA 315-420) protein (GST tag)
MUC1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Mucin 1 (MUC1) (AA 24-158) (Active) protein (hFc Tag)MUC1 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Mucin 1 (MUC1) (AA 24-380) (Active) protein (Fc Tag)MUC1 Origin: Human Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Mucin 1 (MUC1) (AA 1036-1156) protein (Fc Tag)MUC1 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. IA, ScA, ADA, AM
Mucin 1 (MUC1) (AA 1036-1156) protein (His tag)MUC1 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. IA, ScA, ADA, AM
Mucin 1 (MUC1) (AA 1036-1155) protein (His tag)MUC1 Origin: Human Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE.
Mucin 1 (MUC1) (AA 890-1158) protein (His tag)MUC1 Origin: Human Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- 10 mM PBS, pH 7.4±0.2 with 0.2 % Sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Ship at 4°C.Upon receipt, aliquot andstore at -20°C for long term. Avoid repeated freeze and thaw cycles.
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- MUC1 (Mucin 1 (MUC1))
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Alternative Name
- CA153
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Background
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Synonyms: KL-6, MUC-1, MUC-1/SEC, MUC-1/X, MUC1/ZD, Breast carcinoma associated antigen DF3, CA15-3 antigen, CA15.3, Carcinoma associated mucin, CD 227, CD227, CD227 antigen, DF3 antigen, EMA, Episialin, Epithelial membrane antigen, Epithelial mucin tandem repeat sequence, H23 antigen, H23AG, MAM6, MUC 1, MUC-1, Mucin 1, Mucin 1 precursor, Mucin1, Peanut reactive urinary mucin, PEM, PEMT, Polymorphic epithelial mucin, PUM, Tumor associated epithelial membrane antigen, Tumor associated mucin
Description: Purified human Cancer Antigen CA15-3 protein.
Background: CA 15-3, for Carcinoma Antigen 15-3, is a tumor marker for many types of cancer, most notably breast cancer. It is derived from MUC1. CA 15-3 and associated CA 27-29 are different epitopes on the same protein antigen product of the breast cancer-associated MUC1 gene. Elevated CA15-3, in conjunction with alkaline phosphatase (ALP), was found to be associated with an increased chance of early recurrence in breast cancer. Both CA 15-3 and CA 27-29 may be elevated in patients with benign ovarian cysts, benign breast disease, and benign liver disease. Elevations may also be seen in cirrhosis, sarcoidosis and lupus.
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Pathways
- Negative Regulation of intrinsic apoptotic Signaling
Target
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