IL-13 Protein
Quick Overview for IL-13 Protein (ABIN7849723)
Target
See all IL-13 (IL13) ProteinsProtein Type
Origin
Source
Application
Purity
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Purpose
- Recombinant Human IL-13 Protein
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Sterility
- 0.2 μm filtered
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Endotoxin Level
- <0.01 EU/μg by LAL test
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Interleukin 13 (IL13) (AA 21-132) protein (His-Avi Tag)
IL13 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Tris-Bis PAGE
Interleukin 13 (IL13) (AA 19-132) (Active) protein (His tag)IL13 Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Interleukin 13 (IL13) (AA 26-131) (Active) protein (His tag)IL13 Origin: Mouse Host: Human Cells Recombinant > 95 % as determined by SDS-PAGE Active
Interleukin 13 (IL13) (AA 19-132) (Active) proteinIL13 Origin: Human Host: CHO Cells Recombinant > 95 % as analyzed by SDS-PAGE. Active
Interleukin 13 (IL13) (Active) proteinIL13 Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS-PAGE Func Active
Interleukin 13 (IL13) (AA 21-132) (Active) protein (Biotin,His-Avi Tag)IL13 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Interleukin 13 (IL13) (AA 21-132) (Active) protein (Fc Tag)IL13 Origin: Human Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Interleukin 13 (IL13) (AA 21-132) (Active) protein (His tag,AVI tag,Biotin)IL13 Origin: Human Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Interleukin 13 (IL13) (AA 35-146) protein (GST tag)IL13 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Interleukin 13 (IL13) (AA 1-132) protein (GST tag)IL13 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Dissolve the lyophilized protein in distilled water(It is not recommended to reconstitute to a concentration<100 μg/mL.)
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Buffer
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Ship at 4°C.Upon receipt, aliquot and store at -20°C or -80°C for long term. Avoid repeated freeze and thaw cycles.
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- IL-13 (IL13) (Interleukin 13 (IL13))
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Alternative Name
- IL-13
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Background
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Synonyms: IL13, IL-13, P600, interleukin 13
Description: Recombinant human IL-13 is produced by the mammalian system, with the target gene encoding Gly35-Asn146 expressed with 6x His-tag at the C-terminus.
Background: Interleukin 13 (IL-13) is a protein that in humans is encoded by the IL13 gene.IL-13 was first cloned in 1993 and is located on chromosome 5q31.1 with a length of 1.4kb.It has a mass of 13 kDa and folds into 4 alpha helical bundles.The secondary structural features of IL-13 are similar to that of Interleukin 4 (IL-4), however it only has 25 % sequence identity to IL-4 and is capable of IL-4 independent signaling.IL-13 is a cytokine secreted by T helper type 2 (Th2) cells, CD4 cells, natural killer T cell, mast cells, basophils, eosinophils and nuocytes.Interleukin-13 is a central regulator in IgE synthesis, goblet cell hyperplasia, mucus hypersecretion, airway hyperresponsiveness, fibrosis and chitinase up-regulation.It is a mediator of allergic inflammation and different diseases including asthma,and atopic dermatitis.
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Pathways
- JAK-STAT Signaling, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport
Target
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