IL-10 Protein
Quick Overview for IL-10 Protein (ABIN7849728)
Target
See all IL-10 (IL10) ProteinsProtein Type
Origin
Source
Application
Purity
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Purpose
- Recombinant Human IL-10 Protein
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Sterility
- 0.2 μm filtered
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Endotoxin Level
- <0.01 EU/μg by LAL test
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Interleukin 10 (IL10) (AA 19-178) (Active) protein
IL10 Origin: Human Host: CHO Cells Recombinant > 95 % as analyzed by SDS-PAGE and HPLC. Active
Interleukin 10 (IL10) (AA 19-178) (Active) protein (Biotin,His-Avi Tag)IL10 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE Active
Interleukin 10 (IL10) (AA 19-178) (Active) protein (His-Avi Tag)IL10 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Interleukin 10 (IL10) (AA 1-178) protein (GST tag)IL10 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Interleukin 10 (IL10) proteinIL10 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by SDS-PAGE
Interleukin 10 (IL10) (Active) proteinIL10 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS-PAGE Func Active
Interleukin 10 (IL10) (AA 22-178) protein (His tag)IL10 Origin: Hamster Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Interleukin 10 (IL10) (AA 19-178) proteinIL10 Origin: Human Host: Mammalian Cells Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Interleukin 10 (IL10) (AA 19-178) (Active) protein (His tag)IL10 Origin: Rat Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA Active
Interleukin 10 (IL10) (AA 19-178) (Active) protein (His tag)IL10 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA Active
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Dissolve the lyophilized protein in distilled water(It is not recommended to reconstitute to a concentration<100 μg/mL.)
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Buffer
- Lyophilized from a 0.2 μm filtered solution of PBS,4 % Mannitol, pH 7.4.
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Ship at 4°C.Upon receipt, aliquot and store at -20°C or -80°C for long term. Avoid repeated freeze and thaw cycles.
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- IL-10 (IL10) (Interleukin 10 (IL10))
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Alternative Name
- IL-10
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Background
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Synonyms: IL10, CSIF, GVHDS, IL-10, IL10A, TGIF, interleukin 10
Description: Recombinant human IL-10 is produced by the mammalian system, with the target gene encoding Ser19-Asn178 expressed.
Background: Interleukin 10 (IL-10), also known as human cytokine synthesis inhibitory factor (CSIF), is an anti-inflammatory cytokine. In humans, interleukin 10 is encoded by the IL10 gene.IL-10 signals through a receptor complex consisting of two IL-10 receptor-1 and two IL-10 receptor-2 proteins.Consequently, the functional receptor consists of four IL-10 receptor molecules. IL-10 binding induces STAT3 signalling via the phosphorylation of the cytoplasmic tails of IL-10 receptor 1 + IL-10 receptor 2 by JAK1 and TYK2 respectively.
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UniProt
- P22301
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Pathways
- Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location, Cancer Immune Checkpoints
Target
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