Pleiotrophin Protein (PTN) (His tag)
Quick Overview for Pleiotrophin Protein (PTN) (His tag) (ABIN7884556)
Target
See all Pleiotrophin (PTN) ProteinsProtein Type
Origin
Source
Application
Purity
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Purification tag / Conjugate
- This Pleiotrophin protein is labelled with His tag.
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Purpose
- Pleiotrophin, Human
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Sequence
- MGKKEKPEKK VKKSDCGEWQ WSVCVPTSGD CGLGTREGTR TGAECKQTMK TQRCKIPCNW KKQFGAECKY QFQAWGECDL NTALKTRT GSLKRALHNA ECQKTVTISK PCGKLTKPKP QAESKKKKKE GKKQEKMLD with polyhistid ine tag at the C-terminus
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Endotoxin Level
- <0.01 EU per 1 μg protein
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Pleiotrophin (PTN) (AA 33-168) (Active) protein (hFc Tag)
PTN Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Pleiotrophin (PTN) (AA 1-168) protein (GST tag)PTN Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Pleiotrophin (PTN) (Active) proteinPTN Origin: Mouse Host: Baculovirus infected Insect Cells Recombinant > 95 % as determined by SDS-PAGE Active
Pleiotrophin (PTN) protein (His tag)PTN Origin: Mouse Host: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Pleiotrophin (PTN) protein (Fc Tag)PTN Origin: Mouse Host: HEK-293 Cells Recombinant > 85 % as determined by SDS-PAGE
Pleiotrophin (PTN) (AA 33-168) protein (Fc Tag)PTN Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 90 % as determined by SDS-PAGE and Coomassie blue staining. AM, ADA, IA, ScA
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- dissolve in sterile H2O
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Buffer
- PBS, pH 7.4
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Storage
- -20 °C
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Storage Comment
- -20°C
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- Pleiotrophin (PTN)
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Alternative Name
- Pleiotrophin
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Background
- Pleiotrophin (PTN) also known HBBM, HBGF-8, NEGF1, HARP or HB-GAM is a protein that in humans is encoded by the PTN gene. This protein is expressed in the central and peripheral nervous system and also in several non-neural tissues, notably lung, kidney, gut and bone. Pleiotrophin binds anaplastic lymphoma kinase (ALK) which induces MAPK pathway activation, an important step in the anti-apoptotic signaling of PTN and regulation of cell proliferation.
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Molecular Weight
- 19kDa
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Gene ID
- 5764
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NCBI Accession
- NP_002816
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UniProt
- P21246
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Pathways
- RTK Signaling
Target
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