APEX1 Protein

Catalog No. ABIN7933505

This Recombinant APEX1 protein is produced in Escherichia coli (E. coli).

Quick Overview for APEX1 Protein (ABIN7933505)

Target: APEX1 (Apurinic/Apyrimidinic Endonuclease 1 (APEX1))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Purity: Greater than 95 % as determined by reducing SDS-PAGE.

Product Details

Purpose: Recombinant Human Apurinic-Apyrimidinic Endonuclease 1/APE

Sequence: MGPKRGKKGA VAEDGDELRT EPEAKKSKTA AKKNDKEAAG EGPALYEDPP DQKTSPSGKP ATLKICSWNV DGLRAWIKKK GLDWVKEEAP DILCLQETKC SENKLPAELQ ELPGLSHQYW SAPSDKEGYS GVGLLSRQCP LKVSYGIGEE EHDQEGRVIV AEFDSFVLVT AYVPNAGRGL VRLEYRQRWD EAFRKFLKGL ASRKPLVLCG DLNVAHEEID LRNPKGNKKN AGFTPQERQG FGELLQAVPL ADSFRHLYPN TPYAYTFWTY MMNARSKNVG WRLDYFLLSH SLLPALCDSK IRSKALGSDH CPITLYLAL

Sterility: 0.2 μm filtered

Endotoxin Level: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.< br ,>It is not recommended to reconstitute to a concentration less than 100 μ,g,ml.< br ,>Dissolve the lyophilized protein in ddH2O.< br ,>Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Supplied as a 0.2 um filtered solution of 10 mM HEPES, 100 mM KCl, 50 % Glycerol, pH 7.4.

Handling Advice: Please minimize freeze-thaw cycles

Storage: -20 °C

Storage Comment: Store at < -20°C, stable for 6 months after receipt.Please minimize freeze-thaw cycles.

Expiry Date: 6 months

Target Details

Target: APEX1 (Apurinic/Apyrimidinic Endonuclease 1 (APEX1))

Alternative Name: Apurinic-Apyrimidinic Endonuclease 1/APE

Molecular Weight: 35.62kDa

Gene ID: 328

UniProt: P27695

Pathways: DNA Damage Repair, Chromatin Binding, Cell RedoxHomeostasis, Smooth Muscle Cell Migration, Positive Regulation of Response to DNA Damage Stimulus