FGF19 Protein
Quick Overview for FGF19 Protein (ABIN7936824)
Target
See all FGF19 ProteinsProtein Type
Biological Activity
Origin
Source
Purity
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Purpose
- Recombinant Human Fibroblast Growth Factor 19
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Sequence
- MRPLAFSDAG PHVHYGWGDP IRLRHLYTSG PHGLSSCFLR IRADGVVDCA RGQSAHSLLE IKAVALRTVA IKGVHSVRYL CMGADGKMQG LLQYSEEDCA FEEEIRPDGY NVYRSEKHRL PVSLSSAKQR QLYKNRGFLP LSHFLPMLPM VPEEPEDLRG HLESDMFSSP LETDSMDPFG LVTGLEAVRS PSFEK
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Sterility
- 0.2 μm filtered
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Endotoxin Level
- Less than 1 EU/ug of rHuFGF-19 as determined by LAL method.
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Biological Activity Comment
- Assay #1: Fully biologically active when compared to standard. The biological activity is measured by its binding ability in a functional ELISA. Immobilized rHuFGF R4 at 5 μg/ml can bind rHuFGF-19 with a linear range of 3-200 ng/ml.Assay #2: Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using murine Balb/c 3T3 cells is less than 150 ng/ml, corresponding to a specific activity of > 6.7 x103 IU/mg.
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Comment
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Approximately 21.8 kDa, a single non-glycosylated polypeptide chain containing 195 amino acids.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- Lyophilized from a 0.2 um filtered concentrated solution in PBS, pH 7.4.
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles.- 12 months from date of receipt, -20 to -70 °C as supplied.- 1 month, 2 to 8 °C under sterile conditions after reconstitution.- 3 months, -20 to -70 °C under sterile conditions after reconstitution.
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Expiry Date
- 12 months
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- FGF19 (Fibroblast Growth Factor 19 (FGF19))
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Alternative Name
- Fibroblast Growth Factor 19
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Molecular Weight
- 21.8 kDa
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Gene ID
- 9965
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UniProt
- O95750
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Pathways
- RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
Target
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