Thrombopoietin Protein (THPO)
Quick Overview for Thrombopoietin Protein (THPO) (ABIN7956138)
Target
See all Thrombopoietin (THPO) ProteinsProtein Type
Biological Activity
Origin
Source
Purity
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Purpose
- Recombinant Murine Thrombopoietin
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Sequence
- SPVAPACDPR LLNKLLRDSH LLHSRLSQCP DVDPLSIPVL LPAVDFSLGE WKTQTEQSKA QDILGAVSLL LEGVMAARGQ LEPSCLSSLL GQLSGQVRLL LGALQGLLGT QLPLQGRTTA HKDPNALFLS LQQLLRGKVR FLLLVEGPTL CVRRTLPTTA VPSSTSQLLT LNKF
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Sterility
- 0.2 μm filtered
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Endotoxin Level
- Less than 0.1 EU/ug of rMuTPO as determined by LAL method.
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Biological Activity Comment
- Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using human MO7e cells is less than 1.0 ng/ml, corresponding to a specific activity of > 1.0 x106 IU/mg.
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Thrombopoietin (THPO) protein (His tag)
THPO Origin: Mouse Host: Human Cells Recombinant > 95 % as determined by SDS-PAGE
Thrombopoietin (THPO) (AA 23-195) protein (His tag)THPO Origin: Mouse Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Thrombopoietin (THPO) (AA 22-195) protein (His-IF2DI Tag)THPO Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Thrombopoietin (THPO) (AA 1-349) protein (GST tag)THPO Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Thrombopoietin (THPO) (AA 22-356) (Active) protein (His tag)THPO Origin: Mouse Host: Mammalian Cells Recombinant >90 % as determined by SDS-PAGE. SDS, WB, Imm, ELISA, AcA Active
Thrombopoietin (THPO) (AA 22-356) (Active) proteinTHPO Origin: Mouse Host: CHO Cells Recombinant > 95 % as analyzed by SDS-PAGE. Active
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Comment
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Approximately 18.7 kDa, a single non-glycosylated polypeptide chain containing 174 amino acids.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- Lyophilized from a 0.2 um filtered concentrated solution in PBS, pH 7.4, with 5 % Trehalose.
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles.- 12 months from date of receipt, -20 to -70 °C as supplied.- 1 month, 2 to 8 °C under sterile conditions after reconstitution.- 3 months, -20 to -70 °C under sterile conditions after reconstitution.
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Expiry Date
- 12 months
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- Thrombopoietin (THPO)
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Alternative Name
- Thrombopoietin
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Molecular Weight
- 18.7 kDa
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Gene ID
- 21832
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UniProt
- P40226
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Pathways
- JAK-STAT Signaling, Hormone Activity
Target
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