Oncostatin M Protein (OSM)
Quick Overview for Oncostatin M Protein (OSM) (ABIN7937086)
Target
See all Oncostatin M (OSM) ProteinsProtein Type
Biological Activity
Origin
Source
Purity
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Purpose
- Recombinant Human Oncostatin-M, 209a.a.
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Sequence
- AAIGSCSKEY RVLLGQLQKQ TDLMQDTSRL LDPYIRIQGL DVPKLREHCR ERPGAFPSEE TLRGLGRRGF LQTLNATLGC VLHRLADLEQ RLPKAQDLER SGLNIEDLEK LQMARPNILG LRNNIYCMAQ LLDNSDTAEP TKAGRGASQP PTPTPASDAF QRKLEGCRFL HGYHRFMHSV GRVFSKWGES PNRSRRHSPH QALRKGVRR
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Sterility
- 0.2 μm filtered
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Endotoxin Level
- Less than 1 EU/ug of rHuOSM, 209a.a. as determined by LAL method.
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Biological Activity Comment
- Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using human TF-1 cells is less than 2 ng/ml, corresponding to a specific activity of > 5.0 x105 IU/mg.
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Comment
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Approximately 23.7 kDa, a single non-glycosylated polypeptide chain containing 209 amino acids.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- Lyophilized from a 0.2 um filtered concentrated solution in PBS, pH 7.4.
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles.- 12 months from date of receipt, -20 to -70 °C as supplied.- 1 month, 2 to 8 °C under sterile conditions after reconstitution.- 3 months, -20 to -70 °C under sterile conditions after reconstitution.
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Expiry Date
- 12 months
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- Oncostatin M (OSM)
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Alternative Name
- Oncostatin-M
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Molecular Weight
- 23.7 kDa
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Gene ID
- 5008
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UniProt
- P13725
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Pathways
- JAK-STAT Signaling, Negative Regulation of Hormone Secretion
Target
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