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Oncostatin M Protein (OSM)

This Recombinant Oncostatin M protein is produced in Escherichia coli (E. coli).
Catalog No. ABIN7956144
$2,079.00
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Quick Overview for Oncostatin M Protein (OSM) (ABIN7956144)

Target

See all Oncostatin M (OSM) Proteins
Oncostatin M (OSM)

Protein Type

Recombinant

Biological Activity

Active

Origin

  • 38
  • 9
  • 6
  • 2
  • 1
  • 1
Mouse

Source

  • 30
  • 16
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Escherichia coli (E. coli)

Purity

> 96 % by SDS-PAGE and HPLC analyses.
  • Purpose

    Recombinant Murine Oncostatin-M

    Sequence

    NRGCSNSSSQ LLSQLQNQAN LTGNTESLLE PYIRLQNLNT PDLRAACTQH SVAFPSEDTL RQLSKPHFLS TVYTTLDRVL YQLDALRQKF LKTPAFPKLD SARHNILGIR NNVFCMARLL NHSLEIPEPT QTDSGASRST TTPDVFNTKI GSCGFLWGYH RFMGSVGRVF REWDDGSTRS R

    Sterility

    0.2 μm filtered

    Endotoxin Level

    Less than 1 EU/ug of rMuOSM as determined by LAL method.

    Biological Activity Comment

    Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using murine NIH-3T3 cells is less than 1.0 ng/ml, corresponding to a specific activity of > 1.0 x106 IU/mg.
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  • Comment

    Approximately 20.4 kDa, a single non-glycosylated polypeptide chain containing 181 amino acids.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Buffer

    Lyophilized from a 0.2 um filtered concentrated solution in 2 x PBS, pH 7.4, 5 % trehalose.

    Storage

    4 °C,-20 °C,-80 °C

    Storage Comment

    Use a manual defrost freezer and avoid repeated freeze-thaw cycles.- 12 months from date of receipt, -20 to -70 °C as supplied.- 1 month, 2 to 8 °C under sterile conditions after reconstitution.- 3 months, -20 to -70 °C under sterile conditions after reconstitution.

    Expiry Date

    12 months
  • Target

    Oncostatin M (OSM)

    Alternative Name

    Oncostatin-M

    Molecular Weight

    20.4 kDa

    Gene ID

    18413

    UniProt

    P53347

    Pathways

    JAK-STAT Signaling, Negative Regulation of Hormone Secretion
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