JNK Protein
Quick Overview for JNK Protein (ABIN7939323)
Target
See all JNK (MAPK8) ProteinsProtein Type
Origin
Source
Application
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Purpose
- Recombinant MAPK8 (JNK1) protein
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Buffer
- Recombinant MAPK8 (JNK1) protein is in 25 mM Tris pH 8.0, 300 mM NaCl, 20 % glycerol, 0.5 mM TCEP.
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Handling Advice
- Avoid repeated freeze/thaw cycles,keep on ice when not in storage
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Storage
- -80 °C
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Storage Comment
- Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
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- JNK (MAPK8) (Mitogen-Activated Protein Kinase 8 (MAPK8))
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Alternative Name
- MAPK8
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Background
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Protein Background: MAPK8 (Mitogen-activated protein kinase 8) also know as JNK, JNK-46, JNK1, JNK1A2, JNK21B1/2, PRKM8, SAPK1 and SAPK1c. MAPK8 is a serine/threonine-protein kinase involved in various processes such as cell proliferation, differentiation, migration, transformation and programmed cell death. Extracellular stimuli such as proinflammatory cytokines or physical stress stimulate the stress-activated protein kinase/c-Jun N-terminal kinase (SAP/JNK) signaling pathway.
Short Description: Recombinant MAPK8 (JNK1) protein that includes full length of human MAPK8 protein (accession number NP_001310250.1) was expressed in E. coli and contains an N-terminal His tag with a molecular weight of 46.19 kDa. The purity of the protein is ≥ 95 % by SDS-PAGE.
Aliases: JNK, JNK-46, JNK1, JNK1A2, JNK21B1/2, SAPK1, PRKM8
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Pathways
- MAPK Signaling, WNT Signaling, TLR Signaling, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, Signaling of Hepatocyte Growth Factor Receptor, S100 Proteins
Target
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