IFNB1 Protein
Quick Overview for IFNB1 Protein (ABIN934620)
Target
See all IFNB1 ProteinsProtein Type
Biological Activity
Origin
Source
Purity
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Characteristics
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Purified recombinant Human IFN beta protein
Expression System: E.coli
Bioactivity: The EC50 for interferon in a cytopathic effect inhibition assay is ~1 U/mL (Human) and ~5 U/mL (Bovine)
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Interferon, beta 1, Fibroblast (IFNB1) (AA 22-182) protein (His tag)
IFNB1 Origin: Mouse Host: HEK-293 Cells Recombinant The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
Interferon, beta 1, Fibroblast (IFNB1) (AA 22-187) protein (Fc Tag)IFNB1 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Interferon, beta 1, Fibroblast (IFNB1) (AA 22-182) protein (His tag)IFNB1 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95% by SDS-PAGE SDS
Interferon, beta 1, Fibroblast (IFNB1) (AA 1-187) protein (GST tag)IFNB1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Interferon, beta 1, Fibroblast (IFNB1) (AA 22-187), (full length) protein (GST tag)IFNB1 Origin: Human Host: Escherichia coli (E. coli) Recombinant 90 % ELISA
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1000000 U/mL
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Buffer
- PBS with 0.1 % BSA, and 11 % glycerol.
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -80 °C
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Storage Comment
- Aliquot and store at -70 °C or lower.
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- IFNB1 (Interferon, beta 1, Fibroblast (IFNB1))
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Alternative Name
- IFN beta
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Background
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Interferons (IFNs) are proteins made and released by host cells in response to the presence of pathogens-such as viruses, bacteria, or parasites-or tumor cells. They allow communication between cells to trigger the protective defenses of the immune system that eradicate pathogens or tumors. The IFN-beta proteins are produced in large quantities by fibroblasts. They have antiviral activity which is mainly involved in innate immune response. Two types of IFN-beta have been described, IFN-beta1 (IFNB1) and IFN-beta3 (IFNB3).
Alternative Names: RMMB1 protein, B cell interferon protein, Leukocyte interferon protein, Type I interferon protein, Interferon beta protein -
Molecular Weight
- 20 kDa
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Pathways
- JAK-STAT Signaling, TCR Signaling, TLR Signaling, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Autophagy, Inflammasome
Target
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