Complement Factor B Protein (CFB)
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- Target See all Complement Factor B (CFB) Proteins
- Complement Factor B (CFB)
- Protein Type
- Native
- Biological Activity
- Active
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Origin
- Human
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Source
- Human
- Characteristics
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Purified native Human Complement Factor B
Bioactivity: 4, 700 U/mg - 100 % of factor B activity in NHS on a mg/mg basis
Protein Source: Human serum/plasma - Purity
- > 98 % pure
- Top Product
- Discover our top product CFB Protein
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Complement Factor B (CFB) (AA 26-259) protein (His tag)
Crystallography grade CFB Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Complement Factor B (CFB) (AA 23-256) protein (His tag)Crystallography grade CFB Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Complement Factor B (CFB) (AA 260-764) protein (His tag)Crystallography grade CFB Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Complement Factor B (CFB) (AA 257-761) protein (His tag)Crystallography grade CFB Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Complement Factor B (CFB) (AA 26-764) protein (His tag)Crystallography grade CFB Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Complement Factor B (CFB) (AA 23-761) protein (His tag)Crystallography grade CFB Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1.0 mg/mL
- Buffer
- Supplied as a liquid in PBS, pH 7.2, no preservatives added,
- Preservative
- Without preservative
- Precaution of Use
- Donor samples were tested and found to be negative for HBsAg, HTLV-I/II, STS, and for antibodies to HCV, HIV-1 and HIV-II. Nonetheless caution should be used when handling this material as there is a margin of error in all tests.
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- -80 °C
- Storage Comment
- Aliquot and store at -70 °C or lower.
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- Target
- Complement Factor B (CFB)
- Alternative Name
- Complement Factor B (CFB Products)
- Synonyms
- AHUS4 Protein, BF Protein, BFD Protein, CFAB Protein, FB Protein, FBI12 Protein, GBG Protein, H2-Bf Protein, PBF2 Protein, bf Protein, Bf-1 Protein, Brre-Bf Protein, zgc:114032 Protein, Bf Protein, Sp152 Protein, bfb-A Protein, Bf B Protein, LOC397725 Protein, bf/c2 Protein, CFB Protein, AI195813 Protein, AI255840 Protein, B Protein, C2 Protein, Fb Protein, Da1-24 Protein, complement factor B Protein, complement factor B S homeolog Protein, complement factor B L homeolog Protein, CFB Protein, cfb Protein, bf Protein, cfb.S Protein, cfb.L Protein, bf/c2 Protein, LOC100555981 Protein, Cfb Protein
- Background
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Complement factor B is a glycosylated protein composed of a single 93,000 Da polypeptide chain. It is an essential component of the alternative pathway of complement activation and is found in plasma at approximately 200 ug/mL. In the presence of Mg++ factor B binds to C3b and the C3b,B complex can be activated by factor D, a serine protease that circulates as an active trypsin-like serine protease.
Description: Human serum/plasma.
Alternative Names: Recombinant CFB - Molecular Weight
- 93 kDa
- Pathways
- Complement System, Proton Transport, Ribonucleoside Biosynthetic Process
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