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HSP27 Protein

HSPB1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % pure SDS
Catalog No. ABIN934933
  • Target See all HSP27 (HSPB1) Proteins
    HSP27 (HSPB1) (Heat Shock 27kDa Protein 1 (HSPB1))
    Protein Type
    Recombinant
    Origin
    • 8
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 6
    • 5
    • 2
    • 2
    • 1
    Escherichia coli (E. coli)
    Application
    SDS-PAGE (SDS)
    Sequence
    MTERRVPFSL LRGPSWDPFR DWYPHSRLFD QAFGLPRLPE EWSQWLGGSS WPGYVRPLPP AAIESPAVAA PAYSRALSRQ LSSGVSEIRH TADRWRVSLD VNHFAPDELT VKTKDGVVEI TGKHEERQDE HGYISRCFTR KYTLPPGVDP TQVSSSLSPE GTLTVEAPMP KLATQSNEIT IPVTFESRAQ LGGPEAAKSD ETAAK
    Characteristics
    Purified recombinant Human Hsp27 protein
    Expression System: E.coli
    Molecular weight on SDS-PAGE will appear higher.
    Purity
    > 95 % pure
    Endotoxin Level
    < 1.0 EU per µg of protein (determined by LAL method)
    Top Product
    Discover our top product HSPB1 Protein
  • Application Notes
    Hsp27 protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Supplied as a liquid in 20 mM Hepes, pH 7.5, containing 0 mM DTT, and 100 mM KCl.
    Preservative
    Dithiothreitol (DTT)
    Precaution of Use
    This product contains Dithiothreitol: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Storage
    RT/-20 °C
    Storage Comment
    Store at 4 °C for short term storage (1/2 weeks). Aliquot and store at -20 °C or - 70 °C for long term storage.
  • Target
    HSP27 (HSPB1) (Heat Shock 27kDa Protein 1 (HSPB1))
    Alternative Name
    Hsp27 (HSPB1 Products)
    Synonyms
    CMT2F Protein, HMN2B Protein, HS.76067 Protein, HSP27 Protein, HSP28 Protein, Hsp25 Protein, SRP27 Protein, 27kDa Protein, Hsp27 Protein, cb153 Protein, cb660 Protein, hsp1 Protein, hsp25 Protein, hsp27 Protein, id:ibd2821 Protein, sb:cb660 Protein, zgc:103437 Protein, HSPB1 Protein, cmt2f Protein, hs.76067 Protein, hsp28 Protein, heat shock protein family B (small) member 1 Protein, heat shock protein 1 Protein, heat shock protein, alpha-crystallin-related, 1 Protein, heat shock protein family B (small) member 1 L homeolog Protein, HSPB1 Protein, Hspb1 Protein, hspb1 Protein, hspb1.L Protein
    Background
    Hsp27 (also known as the Estrogen-Regulated 24K protein, and hsp 28) is a member of the mammalian small heat shock protein family. Hsp27 is expressed constitutively in many tissues and its expression is increased to high levels after various types of stress including elevated temperatures, toxic metals, drugs and oxidants. Also, Hsp27 is phosphorylated in vivo on three phosphorylation sites (Ser15, Ser78 and Ser82) by protein kinases including MAPKAP kinase 2 and the stress-activated protein kinase SAPK2 (p38). Recombinant human Hsp27 was overexpressed in E. coli and purified by conventional chromatography.
    Alternative Names: Growth-related 25 kDa protein protein, CMT2F protein, Hsp27, Heat shock 27 kDa protein protein, Heat Shock Protein 27 protein, Hsp 28 protein, HspB1 protein, HSP 27 protein, Hsp28 protein, P25 protein, Stress responsive protein 27., DKFZp586P1322 protein, Heat shock 27kDa protein 1 protein, Estrogen regulated 24 kDa protein protein, HS.76067 protein, Hsp27 protein, Heat shock 27 kDa protein 28 kDa heat shock protein protein, Hsp-27 protein, Hsp25 protein, Hsp 27, at shock 25kDa protein 1 protein, Heat shock protein beta-1 protein, Hsp-27, Hspb1 protein, Hsp B1 protein, Hsp27 protein, Heat shock 28kDa protein 1 protein, Heat shock protein beta 1 protein, HspB1 protein, HSP25 protein, SRP27 protein, Heat Shock Protein27 protein, Hsp 27 protein
    Molecular Weight
    22.7 kDa (205 AA)
    Pathways
    MAPK Signaling, Regulation of Actin Filament Polymerization, Signaling Events mediated by VEGFR1 and VEGFR2, Negative Regulation of intrinsic apoptotic Signaling, VEGF Signaling
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