S100A8 Protein (AA 1-93)

Catalog No. ABIN935100

Product Details

Target: S100A8 (S100 Calcium Binding Protein A8 (S100A8))

Protein Type: Recombinant

Protein Characteristics: AA 1-93

Origin: Human

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Sequence: MLTELEKALN SIIDVYHKYS LIKGNFHAVY RDDLKKLLET ECPQYIRKKG ADVWFKELDI NTDGAVNFQE FLILVIKMGV AAHKKSHEES HKE

Characteristics: Purified recombinant Human S100 A8 protein
Expression System: E.coli

Purity: > 90 % pure

Application Details

Application Notes: S100 protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied as a liquid in 20 mM Tris-HCl buffer, pH 8.0, containing 0 mM DTT, and 10 % glycerol.

Preservative: Dithiothreitol (DTT)

Precaution of Use: This product contains Dithiothreitol: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: RT/-20 °C

Storage Comment: Store at 4 °C for short term storage (1/2 weeks). Aliquot and store at -20 °C or - 70 °C for long term storage.

Target Details

Target: S100A8 (S100 Calcium Binding Protein A8 (S100A8))

Alternative Name: S100A8 (S100A8 Products)

Synonyms: 60B8AG Protein, CAGA Protein, CFAG Protein, CGLA Protein, CP-10 Protein, L1Ag Protein, MA387 Protein, MIF Protein, MRP8 Protein, NIF Protein, P8 Protein, Mrp8 Protein, S100A8 Protein, 60B8Ag Protein, AI323541 Protein, B8Ag Protein, CFAg Protein, Caga Protein, p8 Protein, MRP-8 Protein, S100 calcium binding protein A8 Protein, S100 calcium binding protein A8 (calgranulin A) Protein, S100A8 Protein, S100a8 Protein

Background: S100 calcium binding protein A8, also known as MRP8, is a member of the S100 family, EF-hand superfamily of Calcium binding proteins. S100A8 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. It functions both intracellularly and extracellularly, where it binds to RAGE and CD36. Altered expression of this protein is associated with the disease cystic fibrosis. Recombinant human S100A8 was expressed in E. coli and purified by using conventional chromatography techniques.
Alternative Names: S 100, S100, Leukocyte L1 complex light chain protein, S 100 protein, BEE11 protein, CGLA protein, Neutrophil cytosolic 7 kDa protein protein, Migration inhibitory factor-related protein 8 protein, Calprotectin protein, S100 calcium binding protein A8 (calgranulin A) protein, S100A8 protein, Calprotectin L1L subunit protein, CP-10 protein, MA387 protein, p8 protein, CAGA protein, S-100 protein, Protein S100-A8 protein, Chemotactic cytokine CP-10 protein, NIF protein, MIF protein, AI323541 protein, L1Ag protein, S100A8/S100A9 complex protein, S100 calcium binding protein A8 60B8Ag protein, Calgranulin-A protein, MRP-8 protein, CFAG protein, Myeloid-related protein 8 protein, Cystic fibrosisprotein protein, B8Ag protein, Pro-inflammatory S100 cytokine protein, S-100, included protein, included protein, CAGA protein, Urinary stone protein band A.

Molecular Weight: 10.8 Da (93 AA)

Pathways: Transition Metal Ion Homeostasis, Positive Regulation of Endopeptidase Activity, S100 Proteins