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FLIP Protein (AA 1-480)

CFLAR Origin: Human Host: Escherichia coli (E. coli) Recombinant > 85 % pure SDS
Catalog No. ABIN935116
  • Target See all FLIP (CFLAR) Proteins
    FLIP (CFLAR) (CASP8 and FADD-Like Apoptosis Regulator (CFLAR))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-480
    Origin
    • 3
    • 2
    • 1
    • 1
    Human
    Source
    • 3
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Application
    SDS-PAGE (SDS)
    Sequence
    MSAEVIHQVE EALDTDEKEM LLFLCRDVAI DVVPPNVRDL LDILRERGKL SVGDLAELLY RVRRFDLLKR ILKMDRKAVE THLLRNPHLV SDYRVLMAEI GEDLDKSDVS SLIFLMKDYM GRGKISKEKS FLDLVVELEK LNLVAPDQLD LLEKCLKNIH RIDLKTKIQK YKQSVQGAGT SYRNVLQAAI QKSLKDPSNN FRLHNGRSKE QRLKEQLGAQ QEPVKKSIQE SEAFLPQSIP EERYKMKSKP LGICLIIDCI GNETELLRDT FTSLGYEVQK FLHLSMHGIS QILGQFACMP EHRDYDSFVC VLVSRGGSQS VYGVDQTHSG LPLHHIRRMF MGDSCPYLAG KPKMFFIQNY VVSEGQLENS SLLEVDGPAM KNVEFKAQKR GLCTVHREAD FFWSLCTADM SLLEQSHSSP SLYLQCLSQK LRQERKRPLL DLHIELNGYM YDWNSRVSAK EKYYVWLQHT LRKKLILSYT
    Characteristics
    Recombinant human CFLAR protein
    Expression System: E.coli
    Purity
    > 85 % pure
    Top Product
    Discover our top product CFLAR Protein
  • Application Notes
    CFLAR protein has been used in SDS PAGE, and may be suitable for use in other assays
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Liquid. 20 mM Tris-HCl buffer (pH8.0) containing 10 % glycerol.
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Storage
    4 °C/-20 °C/-80 °C
    Storage Comment
    Can be stored at 4 °C short term (1-2 weeks). For long term storage, aliquot and store at -20 °C or -70 °C.
  • Target
    FLIP (CFLAR) (CASP8 and FADD-Like Apoptosis Regulator (CFLAR))
    Alternative Name
    CFLAR (CFLAR Products)
    Synonyms
    Clarp1 Protein, cflar Protein, CFLAR Protein, FLIP Protein, CASH Protein, CASP8AP1 Protein, CLARP Protein, Casper Protein, FLAME Protein, FLAME-1 Protein, FLAME1 Protein, I-FLICE Protein, MRIT Protein, c-FLIP Protein, c-FLIPL Protein, c-FLIPR Protein, c-FLIPS Protein, 2310024N18Rik Protein, A430105C05Rik Protein, Cash Protein, ENSMUSG00000072980 Protein, Flip Protein, Gm9845 Protein, c-Flip Protein, CASP8 and FADD-like apoptosis regulator a Protein, CASP8 and FADD like apoptosis regulator Protein, CASP8 and FADD like apoptosis regulator S homeolog Protein, CASP8 and FADD-like apoptosis regulator Protein, cflara Protein, CFLAR Protein, cflar Protein, cflar.S Protein, Cflar Protein
    Background
    CFLAR, also known as FLIP, is involved in the regulation of apoptosis. It has been designated by independent groups as Casper, I-FLICE, CLARP, FLAME-1 and MRIT. Although its exact role is still being elucidated, it appears to be an important factor in the regulation of apoptosis downstream of all known death receptors. Recombinant human CFLAR protein was expressed in E.coli and denatured using detergent during a conventional chromatography purification process.
    Alternative Names: c-FLIP protein, USURPIN protein, I-FLICE protein, FLIP protein, CLARP protein, MRIT protein, FLAME protein, Casper protein, FLAME1 protein, FLAME-1 protein, CASP8 and FADD-like apoptosis regulator protein, CASH protein
    Molecular Weight
    55.3 kDa (480 AA)
    Pathways
    Apoptosis, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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