FLIP Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag)
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- Target See all FLIP (CFLAR) Proteins
- FLIP (CFLAR) (CASP8 and FADD-Like Apoptosis Regulator (CFLAR))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 3
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This FLIP protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human CFLAR / Casper / I-FLICE (transcript variant 3) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product CFLAR Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- FLIP (CFLAR) (CASP8 and FADD-Like Apoptosis Regulator (CFLAR))
- Alternative Name
- Cflar,casper,i-Flice (CFLAR Products)
- Synonyms
- Clarp1 Protein, cflar Protein, CFLAR Protein, FLIP Protein, CASH Protein, CASP8AP1 Protein, CLARP Protein, Casper Protein, FLAME Protein, FLAME-1 Protein, FLAME1 Protein, I-FLICE Protein, MRIT Protein, c-FLIP Protein, c-FLIPL Protein, c-FLIPR Protein, c-FLIPS Protein, 2310024N18Rik Protein, A430105C05Rik Protein, Cash Protein, ENSMUSG00000072980 Protein, Flip Protein, Gm9845 Protein, c-Flip Protein, CASP8 and FADD-like apoptosis regulator a Protein, CASP8 and FADD like apoptosis regulator Protein, CASP8 and FADD like apoptosis regulator S homeolog Protein, CASP8 and FADD-like apoptosis regulator Protein, cflara Protein, CFLAR Protein, cflar Protein, cflar.S Protein, Cflar Protein
- Background
- The protein encoded by this gene is a regulator of apoptosis and is structurally similar to caspase-8. However, the encoded protein lacks caspase activity and appears to be itself cleaved into two peptides by caspase-8. Several transcript variants encoding different isoforms have been found for this gene, and partial evidence for several more variants exists.
- Molecular Weight
- 25.2 kDa
- NCBI Accession
- NP_001120656
- Pathways
- Apoptosis, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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