FLIP Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2713943

Product Details

Target: FLIP (CFLAR) (CASP8 and FADD-Like Apoptosis Regulator (CFLAR))

Protein Type: Recombinant

Protein Characteristics: Transcript Variant 3

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This FLIP protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human CFLAR / Casper / I-FLICE (transcript variant 3) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: FLIP (CFLAR) (CASP8 and FADD-Like Apoptosis Regulator (CFLAR))

Alternative Name: Cflar,casper,i-Flice (CFLAR Products)

Synonyms: Clarp1 Protein, cflar Protein, CFLAR Protein, FLIP Protein, CASH Protein, CASP8AP1 Protein, CLARP Protein, Casper Protein, FLAME Protein, FLAME-1 Protein, FLAME1 Protein, I-FLICE Protein, MRIT Protein, c-FLIP Protein, c-FLIPL Protein, c-FLIPR Protein, c-FLIPS Protein, 2310024N18Rik Protein, A430105C05Rik Protein, Cash Protein, ENSMUSG00000072980 Protein, Flip Protein, Gm9845 Protein, c-Flip Protein, CASP8 and FADD-like apoptosis regulator a Protein, CASP8 and FADD like apoptosis regulator Protein, CASP8 and FADD like apoptosis regulator S homeolog Protein, CASP8 and FADD-like apoptosis regulator Protein, cflara Protein, CFLAR Protein, cflar Protein, cflar.S Protein, Cflar Protein

Background: The protein encoded by this gene is a regulator of apoptosis and is structurally similar to caspase-8. However, the encoded protein lacks caspase activity and appears to be itself cleaved into two peptides by caspase-8. Several transcript variants encoding different isoforms have been found for this gene, and partial evidence for several more variants exists.

Molecular Weight: 25.2 kDa

NCBI Accession: NP_001120656

Pathways: Apoptosis, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development