Midkine Protein
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- Target See all Midkine (MDK) Proteins
- Midkine (MDK) (Midkine (Neurite Growth-Promoting Factor 2) (MDK))
- Protein Type
- Recombinant
- Biological Activity
- Active
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Sequence
- VAKKKDKVKK GGPGSECAEW AWGPCTPSSK DCGVGFREGT CGAQTQRIRC RVPCNWKKEF GADCKYKFEN WGACDGGTGT KVRQGTLKKA RYNAQCQETI RVTKPCTPKT KAKAKAKKGK GKD
- Characteristics
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Purified recombinant Human Midkine protein
Expression System: E.coli
Bioactivity: Determined by its ability to chemoattract human neutrophils using a concentration range of 0.1-10.0 ng/mL. - Purity
- > 98 % pure
- Endotoxin Level
- < 0.1 ng per µg (1 EU/µg).
- Top Product
- Discover our top product MDK Protein
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Midkine (Neurite Growth-Promoting Factor 2) (MDK) (Active) protein
MDK Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS-PAGE Func Active
Midkine (Neurite Growth-Promoting Factor 2) (MDK) (AA 23-140) protein (His tag)MDK Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by Tris-Bis PAGE
Midkine (Neurite Growth-Promoting Factor 2) (MDK) (AA 21-143) protein (His-Avi Tag)MDK Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by Tris-Bis PAGE
Midkine (Neurite Growth-Promoting Factor 2) (MDK) (AA 21-140) protein (His tag)MDK Origin: Mouse Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Midkine (Neurite Growth-Promoting Factor 2) (MDK) (AA 21-143) protein (His tag)MDK Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % by SDS - PAGE SDS
Midkine (Neurite Growth-Promoting Factor 2) (MDK) (AA 1-143) protein (GST tag)MDK Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Midkine (Neurite Growth-Promoting Factor 2) (MDK) (AA 21-143) protein (His tag)Crystallography grade MDK Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Midkine (Neurite Growth-Promoting Factor 2) (MDK) (AA 23-140) protein (His tag)Crystallography grade MDK Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstitute in water to a concentration of 0.1-1.0 mg/mL.
- Buffer
- Lyophilized from PBS, pH 7.4.
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- RT/-20 °C
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- Target
- Midkine (MDK) (Midkine (Neurite Growth-Promoting Factor 2) (MDK))
- Alternative Name
- Midkine (MDK Products)
- Synonyms
- ARAP Protein, MK Protein, NEGF2 Protein, Mek Protein, MK-B Protein, PTF-alpha-1 Protein, mdk Protein, midkine Protein, negf2 Protein, RIHB Protein, cb518 Protein, fb79b05 Protein, fj33b02 Protein, fj48a12 Protein, mdk2 Protein, plei2 Protein, wu:fb79b05 Protein, wu:fj33b02 Protein, wu:fj48a12 Protein, MK-A Protein, PTF-alpha-2 Protein, X-PTF-alpha1 Protein, XMK Protein, mdk-a Protein, mdk-b Protein, midkine Protein, midkine L homeolog Protein, midkine (neurite growth-promoting factor 2) Protein, midkine b Protein, midkine S homeolog Protein, MDK Protein, Mdk Protein, mdk.L Protein, mdkb Protein, mdk.S Protein
- Background
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Midkine (MK) and its functionally-related protein Pleiotrophin are heparin-binding neurotrophic factors that signal through the same receptor, known as anaplastic lymphoma kinase (ALK). MK plays an important regulatory role in epithelial-mesenchymal interactions during fetal development and in postnatal lung development. MK chemoattracts embryonic neurons, neutrophils and macrophages, and by signaling through the ALK receptor it exerts angiogenic, growth and survival activities during tumorgenesis.
Alternative Names: MK protein, NEGF-2 protein - Molecular Weight
- 13.4 kDa
- Pathways
- RTK Signaling, M Phase, Skeletal Muscle Fiber Development
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