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IGF1B Protein

Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % pure Active
Catalog No. ABIN935735
  • Target See all IGF1B products
    IGF1B (Insulin-Like Growth Factor 3)
    Protein Type
    Recombinant
    Biological Activity
    Active
    Origin
    Human
    Source
    • 1
    Escherichia coli (E. coli)
    Sequence
    LPAVPPQQWA LSAGNGSSEV EVVPFQEVWG RSYCRALERL VDVVSEYPSE VEHMFSPSCV SLLRCTGCCG DENLHCVPVE TANVTMQLLK IRSGDRPSYV ELTFSQHVRC ECRHSPGRQS PDMPGDFRAD APSFLPPRRS LPMLFRMEWG CALTGSQSAV WPSSPVPEEI PRMHPGRNGK KQQRKPLREK MKPERCGDAV PRR
    Characteristics
    Purified recombinant Human PIGF3 protein
    Expression System: E.coli
    Bioactivity: Determined by its ability to chemoattract human monocytes using a concentration range of 5.0-50.0 ng/mL.
    Purity
    > 95 % pure
    Endotoxin Level
    < 0.1 ng per µg (1 EU/µg).
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstitute in water to a concentration of 0.1 - 1.0 mg/mL.
    Buffer
    Supplied lyophilized with no additives.
    Preservative
    Without preservative
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
  • Target
    IGF1B (Insulin-Like Growth Factor 3)
    Alternative Name
    IGF3 (IGF1B Products)
    Synonyms
    IGF-III Protein, igf-3 Protein, igf2 Protein, igf3 Protein, xIGF-3 Protein, insulin-like growth factor 3 L homeolog Protein, igf3.L Protein
    Background
    PlGF-3 is an angiogenic factor that belongs to the cysteine-knot superfamily of growth factors. PlGF-3 is expressed exclusively in the placenta. It signals through the VEGFR-1/FLT1 receptor and stimulates endothelial cell proliferation and migration. PlGF-3 lacks heparin binding affinity.
    Alternative Names: PIGF 3 protein, PIGF 3, PIGF3, Placenta Growth Factor-3 protein, PIGF-3 protein, PIGF-3 protein, PGFL protein, PIGF-3
    Molecular Weight
    45.7 kDa
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