IL-7 Protein
Quick Overview for IL-7 Protein (ABIN988095)
Target
See all IL-7 (IL7) ProteinsBiological Activity
Origin
Source
Purity
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Sequence
- MDCDIEGKDG KQYESVLMVS IDQLLDSMKE IGSNCLNNEF NFFKRHICDA NKEGMFLFRA ARKLRQFLKM NSTGDFDLHL LKVSEGTTIL LNCTGQVKGR KPAALGEAQP TKSLEENKSL KEQKKLNDLC FLKRLLQEIK TCWNKILMGT KE
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Characteristics
- Fully biologically active when compared to standard. The ED50 determined by a cell proliferation assay using murine 2E8 cells is less than 0.5 ng/ml, corresponding to a specific activity of >, 2.0 × 106 IU/mg.
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Endotoxin Level
- Level Less than 1EU/µg of rHuIL-7 as determined by LAL method
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml. Stock solutions should be apportioned into working aliquots and stored at < -20 °C. Further dilutions should be made in appropriate buffered solutions.
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Storage
- 4 °C
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- IL-7 (IL7) (Interleukin 7 (IL7))
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Alternative Name
- Interleukin-7 (IL-7)
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Background
- IL-7 is a hematopoietic growth factor which affects primarily early B and T cells. Produced by thymic stromal cells, spleen cells and keratinocytes, IL-7 can also co-stimulate the proliferation of mature T cells in combination with other factors such as ConA and IL-2. Synonym: Interleukin-7 (IL-7), Human. Formulation: Lyophilized from a 0.2µm filtered concentrated solution in PBS, pH 7.4.
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Molecular Weight
- Approximately 17.4 kD, a single non-glycosylated polypeptide chain containing 153 amino acids.
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Pathways
- JAK-STAT Signaling
Target
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