IL-7 Protein

Catalog No. ABIN988095

This IL-7 protein is expressed in Escherichia coli (E. coli).

Quick Overview for IL-7 Protein (ABIN988095)

Target: IL-7 (IL7) (Interleukin 7 (IL7))

Biological Activity: Active

Origin: Human

Source: Escherichia coli (E. coli)

Purity: > 95 % by SDS-PAGE and HPLC analyses.

Product Details

Sequence: MDCDIEGKDG KQYESVLMVS IDQLLDSMKE IGSNCLNNEF NFFKRHICDA NKEGMFLFRA ARKLRQFLKM NSTGDFDLHL LKVSEGTTIL LNCTGQVKGR KPAALGEAQP TKSLEENKSL KEQKKLNDLC FLKRLLQEIK TCWNKILMGT KE

Characteristics: Fully biologically active when compared to standard. The ED50 determined by a cell proliferation assay using murine 2E8 cells is less than 0.5 ng/ml, corresponding to a specific activity of >, 2.0 × 106 IU/mg.

Endotoxin Level: Level Less than 1EU/µg of rHuIL-7 as determined by LAL method

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml. Stock solutions should be apportioned into working aliquots and stored at < -20 °C. Further dilutions should be made in appropriate buffered solutions.

Storage: 4 °C

Target Details

Target: IL-7 (IL7) (Interleukin 7 (IL7))

Alternative Name: Interleukin-7 (IL-7)

Background: IL-7 is a hematopoietic growth factor which affects primarily early B and T cells. Produced by thymic stromal cells, spleen cells and keratinocytes, IL-7 can also co-stimulate the proliferation of mature T cells in combination with other factors such as ConA and IL-2. Synonym: Interleukin-7 (IL-7), Human. Formulation: Lyophilized from a 0.2µm filtered concentrated solution in PBS, pH 7.4.

Molecular Weight: Approximately 17.4 kD, a single non-glycosylated polypeptide chain containing 153 amino acids.

Pathways: JAK-STAT Signaling