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RSPO1 Proteins

(R-Spondin 1 (RSPO1))
This gene is a member of the R-spondin family and encodes a secreted activator protein with two cystein-rich, furin-like domains and one thrombospondin type 1 domain. In mice, the protein induces the rapid onset of crypt cell proliferation and increases intestinal epithelial healing, providing a protective effect against chemotherapy-induced adverse effects. [provided by RefSeq, Jul 2008].

21 results

RSPO1 Origin: Human Host: Human Cells Recombinant Greater than 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7960373
$664.40
Plus shipping costs $50.00
50 μg (More quantities available)
Shipping to: United States
Delivery in 8 to 12 Business Days
 
  • Type Protein
    • Protein
  • Application
    • Western Blotting (WB)
    • SDS-PAGE (SDS)
    • Immunogen (Imm)
    • Positive Control (PC)
    • ELISA
    • Activity Assay (AcA)
    • Cell Culture (CC)
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Images available
  • Host
    • HEK-293 Cells
    • Escherichia coli (E. coli)
    • HEK-293F Cells
    • Human Cells
    • Bacteria
    • CHO Cells
  • Binding Specificity
    • AA 21-263
    • AA 21-135
    • AA 21-146
    • AA 1-146
    • AA 136-262
    • AA 21-265
  • Conjugate
    • His tag
    • Fc Tag
    • Un-conjugated
  • Protein Type
    • Recombinant
  • Format
    • Lyophilized
  • Biological Activity
    • Biologically Active
  • Supplier
    • antibodies-online
    • Signalway
    • ACROBiosystems
    • Abbexa
    • ProSci
    • ProteoGenix

Latest Publications for our RSPO1 Proteins

Igarashi, Miura, Williams, Jaksch, Kadowaki, Yamauchi, Guarente: "NAD+ supplementation rejuvenates aged gut adult stem cells." in: Aging cell, Vol. 18, Issue 3, pp. e12935, (2020) (PubMed).

Mihaylova, Cheng, Cao, Tripathi, Mana, Bauer-Rowe, Abu-Remaileh, Clavain, Erdemir, Lewis, Freinkman, Dickey, La Spada, Huang, Bell, Deshpande, Carmeliet, Katajisto, Sabatini, Yilmaz: "Fasting Activates Fatty Acid Oxidation to Enhance Intestinal Stem Cell Function during Homeostasis and Aging." in: Cell stem cell, Vol. 22, Issue 5, pp. 769-778.e4, (2019) (PubMed).

Park, Choi, Kim, Cheong, Jeong: "AhR activation by 6-formylindolo[3,2-b]carbazole and 2,3,7,8-tetrachlorodibenzo-p-dioxin inhibit the development of mouse intestinal epithelial cells." in: Environmental toxicology and pharmacology, Vol. 43, pp. 44-53, (2017) (PubMed).

Du, Luo, Li, Tan, Han, Lu, Li, Qian, Zhang, Zhao, Liu: "Lgr4/Gpr48 negatively regulates TLR2/4-associated pattern recognition and innate immunity by targeting CD14 expression." in: The Journal of biological chemistry, Vol. 288, Issue 21, pp. 15131-41, (2013) (PubMed).

Das, Png, Oancea, Hasnain, Lourie, Proctor, Eri, Sheng, Crane, Florin, McGuckin: "Glucocorticoids alleviate intestinal ER stress by enhancing protein folding and degradation of misfolded proteins." in: The Journal of experimental medicine, Vol. 210, Issue 6, pp. 1201-16, (2013) (PubMed).

Aliases for RSPO1 Proteins

R-spondin 1 (Rspo1) Proteins
R-spondin 1 (RSPO1) Proteins
R-spondin 1 (LOC100049655) Proteins
R-spondin 1 (rspo1) Proteins
CRISTIN3 Proteins
R-spondin Proteins
RGD1565558 Proteins
RSPO Proteins
Rspondin Proteins
wu:fj81e05 Proteins
zgc:92153 Proteins
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