Get this product for free
Submit your validation data for this product and get a full refund. I want to validate this product
General |
|
---|---|
Antigen | Macrophage Stimulating 1 Receptor (C-Met-Related tyrosine Kinase) (MST1R) Antibodies |
Epitope | Internal Region Alternatives |
Reactivity | Bat, Gorilla, Human, Monkey Alternatives |
Host | Rabbit Alternatives |
Clonality | |
Conjugate | This MST1R antibody is un-conjugated Alternatives |
Application |
Immunohistochemistry (IHC)
Alternatives
|
Supplier | Log in to see |
Product Details anti-MST1R AntibodyTarget Details MST1R Application Details Handling Images |
|
Specificity | BLAST analysis of the peptide immunogen showed no homology with other human proteins. |
Purification | Immunoaffinity Chromatography |
Immunogen | MST1R antibody was raised against a peptide located near the internal domain of MST1R (Human). |
Target Details MST1RProduct Details anti-MST1R Antibody Application Details Handling Images back to top |
|
Antigen | |
Alternative Name | MST1R (MST1R Antibody Abstract) |
Background | MST1R/Ron, a HGF Receptor/MET-type protein kinase, mediates the biological activities of macrophage-stimulating protein (MSP), a multifunctional cytokine that regulates cell adhesion, motility, growth, and survival. The protein is a membrane-spanning, disulfide-linked heterodimer, which results from cleavage of a glycosylated precursor into 35-kD (alpha) and 150-kD (beta) subunits. Ligand binding results in tyrosine phosphorylation of the beta chain. In knockout studies, MST1R/RON (-/-) mice failed to survive past the periimplantation period. The MST1R/RON gene has been mapped to 3p21, a region of frequent deletion or mutation in small cell lung and renal carcinoma, and has been implicated in the progression of several epithelial cancers. |
Gene ID | 4486 |
UniProt | Q04912 |
Pathways | RTK Signaling |
Application DetailsProduct Details anti-MST1R Antibody Target Details MST1R Handling Images back to top |
|
Application Notes | MST1R antibody can be used in immunohistochemistry starting at 20 μg/mL, and immunofluorescence. |
Restrictions | For Research Use only |
HandlingProduct Details anti-MST1R Antibody Target Details MST1R Application Details Images back to top |
|
Format | Liquid |
Buffer | PBS, 0.1 % sodium azide. |
Preservative | Sodium azide |
Precaution of Use | This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
Handling Advice | As with all antibodies avoid freeze/thaw cycles. |
Storage | 4 °C/-80 °C |
Storage Comment | MST1R antibody should be stored long term (months) at -80 °C and short term (days) at 4 °C. |
ImagesProduct Details anti-MST1R Antibody Target Details MST1R Application Details Handling back to top |
|
Supplier Images |