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SCN9A Products

(Sodium Channel, Voltage-Gated, Type IX, alpha Subunit (SCN9A))
This gene encodes a voltage-gated sodium channel which plays a significant role in nociception signaling. Mutations in this gene have been associated with primary erythermalgia, channelopathy-associated insensitivity to pain, and paroxysmal extreme pain disorder. [provided by RefSeq, Aug 2009].

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Featured SCN9A Categories

SCN9A Antibodies

High quality antibodies with extensive validation data.

SCN9A ELISA Kits

Reliable ELISA kits for a wide range of species.

SCN9A Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended SCN9A Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application IHC, WB, IF, IP, ICC, AA
Validations
  • (1)
  • (5)
Cat. No. ABIN361773
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application IHC, WB, IF, IP, ICC, AA
Validations
  • (5)
Cat. No. ABIN2483099
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application IHC, WB, IF, IP, ICC, AA
Validations
  • (5)
Cat. No. ABIN2483098
Quantity 100 μg
Datasheet Datasheet

Recommended SCN9A ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Monkey
Analytical Method
Validations
Cat. No. ABIN1503598
Quantity 96 tests
Datasheet Datasheet
Reactivity Goat
Analytical Method
Validations
Cat. No. ABIN1503595
Quantity 96 tests
Datasheet Datasheet
Reactivity Dog
Analytical Method
Validations
Cat. No. ABIN1503597
Quantity 96 tests
Datasheet Datasheet

Recommended SCN9A Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (3)
Cat. No. ABIN3095280
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1319285
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3076522
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our SCN9A products

Vandael, Ottaviani, Legros, Lefort, Guérineau, Allio, Carabelli, Carbone: "Reduced availability of voltage-gated sodium channels by depolarization or blockade by tetrodotoxin boosts burst firing and catecholamine release in mouse chromaffin cells." in: The Journal of physiology, Vol. 593, Issue 4, pp. 905-27, (2015) (PubMed).

Lu, Ikeda, Puhl: "A 3.7 kb fragment of the mouse Scn10a gene promoter directs neural crest but not placodal lineage EGFP expression in a transgenic animal." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 35, Issue 20, pp. 8021-34, (2015) (PubMed).

Camargos, Bosmans, Rego, Mourão, Schwartz: "The Scorpion Toxin Tf2 from Tityus fasciolatus Promotes Nav1.3 Opening." in: PLoS ONE, Vol. 10, Issue 6, pp. e0128578, (2015) (PubMed).

Ngwainmbi, De, Smith, El-Hage, Fitting, Kang, Dewey, Hauser, Akbarali: "Effects of HIV-1 Tat on enteric neuropathogenesis." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 34, Issue 43, pp. 14243-51, (2014) (PubMed).

Eom, Zhang, Wang, Lay, Fak, Noebels, Darnell: "NOVA-dependent regulation of cryptic NMD exons controls synaptic protein levels after seizure." in: eLife, Vol. 2, pp. e00178, (2013) (PubMed).

Melemedjian, Khoutorsky, Sorge, Yan, Asiedu, Valdez, Ghosh, Dussor, Mogil, Sonenberg, Price: "mTORC1 inhibition induces pain via IRS-1-dependent feedback activation of ERK." in: Pain, Vol. 154, Issue 7, pp. 1080-91, (2013) (PubMed).

Liang, Fan, Tao, Yaster, Tao: "Protein kinase B/Akt is required for complete Freund's adjuvant-induced upregulation of Nav1.7 and Nav1.8 in primary sensory neurons." in: The journal of pain : official journal of the American Pain Society, Vol. 14, Issue 6, pp. 638-47, (2013) (PubMed).

Dustrude, Wilson, Ju, Xiao, Khanna: "CRMP2 protein SUMOylation modulates NaV1.7 channel trafficking." in: The Journal of biological chemistry, Vol. 288, Issue 34, pp. 24316-31, (2013) (PubMed).

Campbell, Main, Fitzgerald: "Functional expression of the voltage-gated Na?-channel Nav1.7 is necessary for EGF-mediated invasion in human non-small cell lung cancer cells." in: Journal of cell science, Vol. 126, Issue Pt 21, pp. 4939-49, (2013) (PubMed).

Laedermann, Syam, Pertin, Decosterd, Abriel: "?1- and ?3- voltage-gated sodium channel subunits modulate cell surface expression and glycosylation of Nav1.7 in HEK293 cells." in: Frontiers in cellular neuroscience, Vol. 7, pp. 137, (2013) (PubMed).

Synonyms and alternative names related to SCN9A

sodium channel, voltage-gated, type IX, alpha subunit (SCN9A), sodium voltage-gated channel alpha subunit 9 (SCN9A), sodium channel protein type 9 subunit alpha (LOC100016648), sodium channel, voltage-gated, type IX, alpha (Scn9a), sodium voltage-gated channel alpha subunit 9 (Scn9a), DKFZp459G084, ETHA, FEB3B, GEFSP7, mKIAA4197, Nav1.7, NE-NA, NENA, PN1, Scn2a, SCN9A, SFNP

Protein level used designations for SCN9A

  • sodium channel, voltage-gated, type IX, alpha subunit
  • sodium channel protein type 9 subunit alpha-like
  • peripheral sodium channel 1
  • sodium channel 25
  • sodium channel protein type 9 subunit alpha
  • sodium channel protein type IX subunit alpha
  • sodium channel, voltage-gated, type IX, alpha polypeptide
  • voltage-gated sodium channel alpha subunit Nav1.7
  • voltage-gated sodium channel subunit alpha Nav1.7
  • sodium channel, voltage-gated, type 9, alpha polypeptide
  • hNE-Na
  • neuroendocrine sodium channel
  • nas
  • schwann cell sodium channel
  • sodium channel alpha-subunit
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