Mouse anti-Human IgG3 (Hinge Region) Antibody

Catalog No. ABIN135664

Quick Overview for Mouse anti-Human IgG3 (Hinge Region) Antibody (ABIN135664)

Target: IgG3

Clonality: Monoclonal

Application: ELISA, Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISpot, Multiplex Assay (MA), Purification (Purif), Surface Plasmon Resonance (SPR)

Clone: HP6050

Isotype: IgG1

Product Details

Binding Specificity: Hinge Region

Reactivity: Human

Host: Mouse

Purpose: Mouse Anti-Human IgG3 Hinge-UNLB

Specificity: Reacts with the hinge region of the heavy chain of human IgG3 as demonstrated by ELISA

Characteristics: Purified Anti-Human IgG3 Hinge antibody for use in ELISA, flow cytometry, immunohistochemistry, western blotting, immunoprecipitation, ELISpot, surface plasmon resonance, microarray, purification, and multiplex assays.

Immunogen: Human IgG3 myeloma protein

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Borate buffered saline, pH 8.2

Storage: 4 °C

Storage Comment: 2-8°C

References

Dogan, Kozhaya, Placek, Gunter, Yigit, Hardy, Plassmeyer, Coatney, Lillard, Bukhari, Kleinberg, Hayes, Arditi, Klapper, Merin, Liang, Gupta, Alpan, Unutmaz: "SARS-CoV-2 specific antibody and neutralization assays reveal the wide range of the humoral immune response to virus." in: Communications biology, Vol. 4, Issue 1, pp. 129, (2021) (PubMed).

Haag, Schneider, Mason, Tuncel, Andersson, Peters, Burkhardt, Holmdahl: "Mass spectrometric analysis of citrullinated type II collagen reveals new citrulline-specific autoantibodies, which bind to human arthritic cartilage." in: Arthritis & rheumatology (Hoboken, N.J.), (2014) (PubMed).

Jackson, Lucas, Melancon, Desai: "Clinical relevance and IgG subclass determination of non-HLA antibodies identified using endothelial cell precursors isolated from donor blood." in: Transplantation, Vol. 92, Issue 1, pp. 54-60, (2011) (PubMed).

Xu, Chen, Zhao: "High potential to reverse the inhibition of myeloperoxidase by ceruloplasmin of anti-myeloperoxidase autoantibodies of IgG3 subclass." in: Autoimmunity, (2011) (PubMed).

Xu, Chen, Cui, Zhao: "Influence of myeloperoxidase by anti-myeloperoxidase antibodies and its association with the disease activity in microscopic polyangiitis." in: Rheumatology (Oxford, England), Vol. 49, Issue 11, pp. 2068-75, (2010) (PubMed).

Target Details

Target: IgG3

Target Type: Antibody

Background:

Description: Mouse Anti-Human IgG3 Hinge-UNLB

NCBI_Official_Symbol: IGHG3

Gene ID: 3502

UniProt: P01860