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Rat anti-Mouse IgE Antibody

EIA Monoclonal LO-ME-2 IgG2a unconjugated
Catalog No. ABIN181023
  • Target See all IgE products
    IgE
    Reactivity
    • 48
    • 30
    • 10
    • 10
    • 5
    • 4
    • 2
    • 1
    Mouse
    Host
    • 58
    • 18
    • 10
    • 10
    • 4
    • 1
    Rat
    Clonality
    • 66
    • 28
    Monoclonal
    Application
    • 55
    • 39
    • 30
    • 20
    • 20
    • 15
    • 12
    • 10
    • 10
    • 8
    • 8
    • 6
    • 5
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Enzyme Immunoassay (EIA)
    Purification
    Affinity chromatography
    Immunogen
    Purified IgE from Balb/c mice.
    Clone
    LO-ME-2
    Isotype
    IgG2a
  • Application Notes
    ELISA.

    Other applications not tested.
    Otimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    PBS, pH 7.2 containing 0.09 % Sodium Azide as preservative.
    Preservative
    Sodium azide
    Precaution of Use
    WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -28 °C for longer.
  • Target
    IgE
    Abstract
    IgE Products
    Background
    IgE mediates the immune responses in the pathogenesis of allergic asthmas. This has been shown in the successful use of recombinant 'humanised' monoclonal antibodies against IgE in the treatment of moderate-to-severe allergic asthma where the antibody forms complexes with free IgE and blocks its interaction with mast cells and basophils.Synonyms: Mouse Immunoglobulin E
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