SIGIRR Proteins
(Single Immunoglobulin and Toll-Interleukin 1 Receptor (TIR) Domain (SIGIRR))
Acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways. Attenuates the recruitment of receptor-proximal signaling components to the TLR4 receptor, probably through an TIR-TIR domain interaction with TLR4. Through its extracellular domain interferes with the heterodimerization of Il1R1 and IL1RAP (By similarity).
| Catalog no. | Product | Reactivity | Host / Clonality | Application | Price & lead time |
|---|---|---|---|---|---|
| SIGIRR Protein (His-Fc tag) | Mouse | HEK-293 Cells |
|
$1,029.34
View price
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| SIGIRR Protein (AA 1-410) (GST tag) | Human | Wheat germ |
|
$475.39
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|
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| SIGIRR Protein (GST tag,His tag) | Mouse | Escherichia coli (E. coli) |
|
$345.09
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|
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| SIGIRR Protein (AA 1-118, C-Term, Extracellular Domain) (Fc Tag) | Human | HEK-293 Cells |
|
$273.13
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|
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| SIGIRR Protein (AA 1-410) (Strep Tag) | Human | Cell-free protein synthesis (CFPS) |
|
starts at $19,692.86
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|
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| SIGIRR Protein (AA 1-409) (Strep Tag) | Mouse | Cell-free protein synthesis (CFPS) |
|
starts at $19,692.86
View price
|
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| SIGIRR Protein (AA 1-118) (Fc Tag) | Human | HEK-293 Cells |
|
$650.23
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|
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| SIGIRR Protein (His tag) | Human | HEK-293 Cells |
|
$926.62
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|
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| SIGIRR Protein (AA 1-118) (His tag) | Rat | Escherichia coli (E. coli) |
|
$769.83
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|
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| SIGIRR Protein (AA 1-117) (His tag,GST tag) | Mouse | Escherichia coli (E. coli) |
|
$769.83
View price
|
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| SIGIRR Protein (AA 1-118) (His tag) | Human | Escherichia coli (E. coli) |
|
$497.41
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|
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| SIGIRR Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag) | Human | HEK-293 Cells |
|
$1,112.40
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|
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| SIGIRR Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag) | Human | HEK-293 Cells |
|
$1,112.40
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|
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| SIGIRR Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag) | Human | HEK-293 Cells |
|
$1,112.40
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|
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| SIGIRR Protein (AA 1-117) (His tag) | Mouse | Yeast |
|
$680.70
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|
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| SIGIRR Protein (AA 1-118) (His tag) | Rat | Yeast |
|
$2,387.35
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|
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| SIGIRR Protein (partial) (His-SUMO Tag) | Mouse | Escherichia coli (E. coli) |
|
$829.40
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|
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| SIGIRR Protein (AA 2-117) (GST tag,His tag) | Mouse | Bacteria |
|
$500.50
View price
|
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| SIGIRR Protein (AA 1-118) (His tag) | Human | Bacteria |
|
$500.50
View price
|
|
| SIGIRR Protein (GST tag,His tag) | Mouse | Escherichia coli (E. coli) |
|
$478.00
View price
|
Protein
- WB (Western Blotting: Validation image available)
- Origin
- Mouse
- Host
- HEK-293 Cells
- Protein Type
- Recombinant
- Purity
- > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7198052
$1,029.34
Plus shipping costs $50.00
100 μg
Shipping to:
United States
Delivery in 11 to 15 Business Days
Protein
- AP (Affinity Purification: Listed application)
- AA (Antibody Array: Listed application)
- ELISA (ELISA: Listed application)
- WB (Western Blotting: Listed application)
- Origin
- Human
- Host
- Wheat germ
- Protein Type
- Recombinant
Catalog No. ABIN1319981
$475.39
Plus shipping costs $50.00, if applicable $20.00 dry ice
10 μg
(More quantities available)
Shipping to:
United States
Delivery in 11 to 14 Business Days
Protein
- SDS (SDS-PAGE: Listed application)
- WB (Western Blotting: Listed application)
- ELISA (ELISA: Listed application)
- Origin
- Mouse
- Host
- Escherichia coli (E. coli)
- Protein Type
- Recombinant
Catalog No. ABIN7580829
$345.09
Plus shipping costs $50.00
100 μg
Shipping to:
United States
Delivery in 12 to 15 Business Days
Protein
- Origin
- Human
- Host
- HEK-293 Cells
- Protein Type
- Recombinant
- Purity
- >90 % (SDS-PAGE)
Catalog No. ABIN6253499
$273.13
Plus shipping costs $50.00
10 μg
(More quantities available)
Shipping to:
United States
Delivery in 5 to 10 Business Days
Protein
- SDS (SDS-PAGE: Listed application)
- WB (Western Blotting: Listed application)
- ELISA (ELISA: Listed application)
- Grade
- custom-made
- Origin
- Human
- Host
- Cell-free protein synthesis (CFPS)
- Protein Type
- Recombinant
- Purity
- approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
Catalog No. ABIN3115630
starts at
$19,692.86
Plus shipping costs $50.00, if applicable $20.00 dry ice
250 μg
Shipping to:
United States
Delivery in 55 to 67 Business Days
Protein
- SDS (SDS-PAGE: Listed application)
- WB (Western Blotting: Listed application)
- ELISA (ELISA: Listed application)
- Grade
- custom-made
- Origin
- Mouse
- Host
- Cell-free protein synthesis (CFPS)
- Protein Type
- Recombinant
- Purity
- approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
Catalog No. ABIN3130345
starts at
$19,692.86
Plus shipping costs $50.00, if applicable $20.00 dry ice
250 μg
Shipping to:
United States
Delivery in 55 to 67 Business Days
Protein
- AM (Affinity Measurement: Listed application)
- ADA (Antibody Drug Assay: Listed application)
- IA (Immunoassay: Listed application)
- ScA (Screening Assay: Listed application)
- Origin
- Human
- Host
- HEK-293 Cells
- Protein Type
- Recombinant
- Purity
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Catalog No. ABIN7853696
$650.23
Plus shipping costs $50.00
100 μg
(More quantities available)
Shipping to:
United States
Delivery in 12 to 15 Business Days
Protein
- Origin
- Human
- Host
- HEK-293 Cells
- Protein Type
- Recombinant
- Purity
- > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7198051
$926.62
Plus shipping costs $50.00
100 μg
(More quantities available)
Shipping to:
United States
Delivery in 11 to 15 Business Days
Protein
- SDS (SDS-PAGE: Listed application)
- WB (Western Blotting: Listed application)
- Imm (Immunogen: Listed application)
- PC (Positive Control: Listed application)
- Origin
- Rat
- Host
- Escherichia coli (E. coli)
- Protein Type
- Recombinant
- Purity
- > 97 %
Catalog No. ABIN7402238
$769.83
Plus shipping costs $50.00
100 μg
(More quantities available)
Shipping to:
United States
Delivery in 13 to 17 Business Days
Protein
- SDS (SDS-PAGE: Listed application)
- WB (Western Blotting: Listed application)
- Imm (Immunogen: Listed application)
- PC (Positive Control: Listed application)
- Origin
- Mouse
- Host
- Escherichia coli (E. coli)
- Protein Type
- Recombinant
- Purity
- > 95 %
Catalog No. ABIN7403150
$769.83
Plus shipping costs $50.00
100 μg
(More quantities available)
Shipping to:
United States
Delivery in 13 to 17 Business Days
Protein
- SDS (SDS-PAGE: Listed application)
- WB (Western Blotting: Listed application)
- Imm (Immunogen: Listed application)
- PC (Positive Control: Listed application)
- Origin
- Human
- Host
- Escherichia coli (E. coli)
- Protein Type
- Recombinant
- Purity
- > 90 %
Catalog No. ABIN7402235
$497.41
Plus shipping costs $50.00
100 μg
(More quantities available)
Shipping to:
United States
Delivery in 13 to 17 Business Days
Protein
- WB (Western Blotting: Validation image available)
- AbP (Antibody Production: Listed application)
- STD (Standard: Listed application)
- Origin
- Human
- Host
- HEK-293 Cells
- Protein Type
- Recombinant
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
Catalog No. ABIN2732046
$1,112.40
Plus shipping costs $50.00, if applicable $20.00 dry ice
20 μg
Shipping to:
United States
Delivery in 11 to 12 Business Days
Protein
- WB (Western Blotting: Validation image available)
- AbP (Antibody Production: Listed application)
- STD (Standard: Listed application)
- Origin
- Human
- Host
- HEK-293 Cells
- Protein Type
- Recombinant
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
Catalog No. ABIN2732047
$1,112.40
Plus shipping costs $50.00, if applicable $20.00 dry ice
20 μg
Shipping to:
United States
Delivery in 11 to 12 Business Days
Protein
- WB (Western Blotting: Validation image available)
- AbP (Antibody Production: Listed application)
- STD (Standard: Listed application)
- Origin
- Human
- Host
- HEK-293 Cells
- Protein Type
- Recombinant
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
Catalog No. ABIN2732048
$1,112.40
Plus shipping costs $50.00, if applicable $20.00 dry ice
20 μg
Shipping to:
United States
Delivery in 11 to 12 Business Days
Protein
- ELISA (ELISA: Listed application)
- Origin
- Mouse
- Host
- Yeast
- Protein Type
- Recombinant
- Purity
- > 90 %
Catalog No. ABIN7479429
$680.70
Plus shipping costs $50.00
100 μg
(More quantities available)
Shipping to:
United States
Delivery in 60 to 72 Business Days
Protein
- ELISA (ELISA: Listed application)
- Origin
- Rat
- Host
- Yeast
- Protein Type
- Recombinant
- Purity
- > 90 %
Catalog No. ABIN1631222
$2,387.35
Plus shipping costs $50.00
1 mg
Shipping to:
United States
Delivery in 60 to 72 Business Days
Protein
- Origin
- Mouse
- Host
- Escherichia coli (E. coli)
- Protein Type
- Recombinant
- Purity
- Greater than 90 % as determined by SDS-PAGE.
Catalog No. ABIN7958516
$829.40
Plus shipping costs $50.00
100 μg
(More quantities available)
Shipping to:
United States
Delivery in 8 to 12 Business Days
Protein
- Origin
- Mouse
- Host
- Bacteria
- Protein Type
- Recombinant
Catalog No. ABIN7820271
$500.50
Plus shipping costs $50.00, if applicable $20.00 dry ice
100 μg
Shipping to:
United States
Delivery in 7 to 10 Business Days
Catalog No. ABIN7818801
$500.50
Plus shipping costs $50.00, if applicable $20.00 dry ice
100 μg
Shipping to:
United States
Delivery in 7 to 10 Business Days
Protein
- SDS (SDS-PAGE: Listed application)
- WB (Western Blotting: Listed application)
- Imm (Immunogen: Listed application)
- ELISA (ELISA: Listed application)
- Origin
- Mouse
- Host
- Escherichia coli (E. coli)
- Protein Type
- Recombinant
Catalog No. ABIN7952095
$478.00
Plus shipping costs $50.00
100 μg
(More quantities available)
Shipping to:
United States
Delivery in 8 to 12 Business Days
Aliases for SIGIRR Proteins
single Ig and TIR domain containing (SIGIRR) Proteinssingle immunoglobulin and toll-interleukin 1 receptor (TIR) domain (Sigirr) Proteins
single immunoglobulin and toll-interleukin 1 receptor (TIR) domain (sigirr) Proteins
single Ig and TIR domain containing (Sigirr) Proteins
AI256711 Proteins
RGD1306732 Proteins
sc:d148 Proteins
TIR8 Proteins
Did you look for something else?
- SIDT1 Proteins
- Sidekick Cell Adhesion Molecule 2 Proteins
- Sialoadhesin/CD169 Proteins
- Sialidase 4 Proteins
- Sialic Acid Binding Ig-Like Lectin 15 Proteins
- SIAH2 Proteins
- SIAH1 Proteins
- SIAE Proteins
- Shugoshin Proteins
- SHQ1 Proteins
- SHPK Proteins
- SHP1 Proteins
- SHOX2 Proteins
- SHOX Proteins
- Shootin-1 Proteins
- SHoc2/Sur8 Proteins
- SHMT2 Proteins
- SHMT1 Proteins
- Shisa9 Proteins
- SHISA5 Proteins
- SIGLEC10 Proteins
- SIGLEC12 Proteins
- SIGLEC14 Proteins
- SIGLEC5 Proteins
- SIGLEC6 Proteins
- SIGLEC7 Proteins
- SIGLEC8 Proteins
- SIGLEC9 Proteins
- SIGMAR1 Proteins
- Signal Transducing Adaptor Family Member 2 Proteins
- Signal-Regulatory Protein alpha Proteins
- Signal-Regulatory Protein beta 1 Proteins
- SIK2 Proteins
- SIKE1 Proteins
- SIL1 Proteins
- SIM1 Proteins
- SIM2 Proteins
- SIN3A Proteins
- Sin3A-Associated Protein, 130kDa Proteins
- SIN3B Proteins
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