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SMG7 Products

(Smg-7 Homolog, Nonsense Mediated mRNA Decay Factor (SMG7))
This gene encodes a protein that is essential for nonsense-mediated mRNA decay (NMD)\; a process whereby transcripts with premature termination codons are targeted for rapid degradation by a mRNA decay complex. The mRNA decay complex consists, in part, of this protein along with proteins SMG5 and UPF1. The N-terminal domain of this protein is thought to mediate its association with SMG5 or UPF1 while the C-terminal domain interacts with the mRNA decay complex. This protein may therefore couple changes in UPF1 phosphorylation state to the degradation of NMD-candidate transcripts. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Aug 2011].

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Featured SMG7 Categories

SMG7 Antibodies

High quality antibodies with extensive validation data.

SMG7 ELISA Kits

Reliable ELISA kits for a wide range of species.

SMG7 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended SMG7 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, IF, IHC
Validations
  • (3)
Cat. No. ABIN7166132
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IF, IHC, ICC
Validations
  • (2)
Cat. No. ABIN6259540
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IHC (p)
Validations
  • (2)
Cat. No. ABIN1501000
Quantity 100 μL
Datasheet Datasheet

Recommended SMG7 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN5648325
Quantity 96 tests
Datasheet Datasheet

Recommended SMG7 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3135214
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3095443
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN5710916
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our SMG7 products

Lykke-Andersen, Chen, Ardal, Lilje, Waage, Sandelin, Jensen: "Human nonsense-mediated RNA decay initiates widely by endonucleolysis and targets snoRNA host genes." in: Genes & development, Vol. 28, Issue 22, pp. 2498-517, (2014) (PubMed).

Sakaki, Yoshina, Shen, Han, DeSantis, Xiong, Mitani, Kaufman: "RNA surveillance is required for endoplasmic reticulum homeostasis." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Issue 21, pp. 8079-84, (2012) (PubMed).

Synonyms and alternative names related to SMG7

Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans) (Smg7), SMG7, nonsense mediated mRNA decay factor (SMG7), 9430023P16Rik, C1orf16, EST1C, mKIAA0250, SGA56M

Protein level used designations for SMG7

  • EST1-like protein C
  • protein SMG7
  • EST1 telomerase component homolog C
  • breast cancer-associated antigen SGA-56M
  • ever shorter telomeres 1C
  • smg-7 homolog, nonsense mediated mRNA decay factor
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