This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like most family members. This protein interacts with phosphatidylinositol-3-phosphate, and is involved in protein trafficking. [provided by RefSeq, Jul 2008].
Latest Publications for our Sorting Nexin 3 Proteins
Xu, Hortsman, Seet, Wong, Hong: "SNX3 regulates endosomal function through its PX-domain-mediated interaction with PtdIns(3)P." in: Nature cell biology, Vol. 3, Issue 7, pp. 658-66, (2001) (PubMed).
Haft, de la Luz Sierra, Barr, Haft, Taylor: "Identification of a family of sorting nexin molecules and characterization of their association with receptors." in: Molecular and cellular biology, Vol. 18, Issue 12, pp. 7278-87, (1998) (PubMed).
Aliases for Sorting Nexin 3 Proteins
sorting nexin 3 (SNX3) Proteins sorting nexin 3 L homeolog (snx3.L) Proteins sorting nexin 3 (snx3) Proteins potential phosphoinositide-binding protein similar to S. cerevisiae GRD19 (YOR357C) late Golgi protein involved in retrieval of proteins from prevacuolar compartment; same as cosmid orf Ca41C10.03 (GRD19) Proteins sorting nexin 3 (Snx3) Proteins Grd19 Proteins MCOPS8 Proteins sdp3 Proteins SDP3 Proteins SNX3 Proteins snx3a Proteins wu:fb53a08 Proteins zgc:123189 Proteins