anti-Human BMP7 antibody for Enzyme Immunoassay

Recommended BMP7 Antibody (supplied by: Log in to see )

Antigen
Bone Morphogenetic Protein 7 (BMP7) Antibodies
  • bmp-7
  • bmp7
  • op-1
  • BMP7
  • zgc:153025
  • OP-1
  • OP1
  • BMP-7
  • fb83f09
  • wu:fb83f09
  • bone morphogenetic protein 7
  • bone morphogenetic protein 7, gene 1 L homeolog
  • bone morphogenetic protein 7b
  • bone morphogenetic protein 7, gene 2 L homeolog
  • bone morphogenetic protein 7a
  • BMP7
  • bmp7.1.L
  • LOC100136282
  • bmp7b
  • Bmp7
  • LOC100008826
  • bmp7.2.L
  • bmp7a
Epitope
N-Term
31
15
13
12
11
10
7
7
6
6
5
5
3
3
3
3
3
2
2
2
1
1
1
1
1
1
Reactivity
Human
240
83
55
9
8
6
5
5
4
3
2
1
1
1
1
Host
Rabbit
167
81
10
3
1
Clonality
Polyclonal
Conjugate
This BMP7 antibody is un-conjugated
23
13
11
6
6
6
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
207
139
95
22
21
17
15
14
13
6
3
3
3
2
2
1
1
1
1
1
1
Supplier
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Catalog No. ABIN357185
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
4 ABIN121162 EIA WB Mouse IgG1 AA 293-431 Log in to see 4-00E-007 4
1 ABIN114065 EIA Rabbit AA 1-17, N-Term Log in to see Polyclonal 0
1 ABIN320370 EIA WB Mouse IgG1 AA 293-431 Log in to see 4-00E-007 0
1 ABIN181147 EIA Mouse IgG1 Log in to see 0
1 ABIN181552 EIA Func WB Rabbit Log in to see Polyclonal 0
1 ABIN181549 EIA WB Biotin Rabbit Log in to see Polyclonal 0

General

Antigen Bone Morphogenetic Protein 7 (BMP7) Antibodies
Epitope N-Term
(31), (15), (13), (12), (11), (10), (7), (7), (6), (6), (5), (5), (3), (3), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Reactivity Human
(240), (83), (55), (9), (8), (6), (5), (5), (4), (3), (2), (1), (1), (1), (1)
Host Rabbit
(167), (81), (10), (3), (1)
Clonality
Polyclonal
Conjugate This BMP7 antibody is un-conjugated
(23), (13), (11), (6), (6), (6), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(207), (139), (95), (22), (21), (17), (15), (14), (13), (6), (3), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1)
Pubmed 5 references available
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Product Details anti-BMP7 Antibody

Target Details BMP7 Application Details Handling References for anti-BMP7 antibody (ABIN357185) Images
Specificity This antibody detects Bmp7 at N-term.
Purification Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
Immunogen This BMP7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human Bmp7.
Isotype Ig Fraction
Plasmids, Primers & others

Target Details BMP7

Product Details anti-BMP7 Antibody Application Details Handling References for anti-BMP7 antibody (ABIN357185) Images back to top
Antigen
Alternative Name BMP7 (BMP7 Antibody Abstract)
Background Bone Morphogenetic Protein 7 (BMP7), also known as osteogenic protein 1 (OP1), is produced from a DNA sequence encoding the human BMP2 signal peptide and human BMP2 propeptide (amino acid residues 1 to 282) fused to the human BMP7 mature subunit (amino acid residues 293 to 431). Mature human BMP7, generated after the proteolytic removal of the signal peptide and the propeptide, is a disulfide linked homodimeric protein, comprised of two 139 amino acid residue subunits. Bone Morphogenetic Proteins (BMP) are members of the TGF beta superfamily of cytokines that affect bone and cartilage formation. Similar to other TGF beta family proteins, BMPs are highly conserved across animal species.Synonyms: BMP-7, Bone morphogenetic protein 7, OP1, Osteogenic protein 1
Molecular Weight 49313 Da
Gene ID 655, 9606
UniProt P18075
Pathways Steroid Hormone Mediated Signaling Pathway, Stem Cell Maintenance

Application Details

Product Details anti-BMP7 Antibody Target Details BMP7 Handling References for anti-BMP7 antibody (ABIN357185) Images back to top
Application Notes ELISA: 1/1,000. Western blot: 1/50-1/200. Immunohistochemistry: 1/50-1/100. Immunofluorescence: 1/50-1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-BMP7 Antibody Target Details BMP7 Application Details References for anti-BMP7 antibody (ABIN357185) Images back to top
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) Sodium Azide as preservative.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.

References for anti-BMP7 antibody (ABIN357185)

Product Details anti-BMP7 Antibody Target Details BMP7 Application Details Handling Images back to top
Background publications

Merrihew, Kumar, Heretis, Rueger, Kuettner, Chubinskaya: "Alterations in endogenous osteogenic protein-1 with degeneration of human articular cartilage." in: Journal of orthopaedic research : official publication of the Orthopaedic Research Society, Vol. 21, Issue 5, pp. 899-907, 2003

Greenwald, Groppe, Gray, Wiater, Kwiatkowski, Vale, Choe: "The BMP7/ActRII extracellular domain complex provides new insights into the cooperative nature of receptor assembly." in: Molecular cell, Vol. 11, Issue 3, pp. 605-17, 2003

Maric, Poljak, Zoricic, Bobinac, Bosukonda, Sampath, Vukicevic: "Bone morphogenetic protein-7 reduces the severity of colon tissue damage and accelerates the healing of inflammatory bowel disease in rats." in: Journal of cellular physiology, Vol. 196, Issue 2, pp. 258-64, 2003

Im, Pacione, Chubinskaya, Van Wijnen, Sun, Loeser: "Inhibitory effects of insulin-like growth factor-1 and osteogenic protein-1 on fibronectin fragment- and interleukin-1beta-stimulated matrix metalloproteinase-13 expression in human chondrocytes." in: The Journal of biological chemistry, Vol. 278, Issue 28, pp. 25386-94, 2003

Lee, Yang, Jin, Chang, Bang, Kim: "Bone morphogenetic protein-7 inhibits constitutive and interleukin-1 beta-induced monocyte chemoattractant protein-1 expression in human mesangial cells: role for JNK/AP-1 pathway." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 170, Issue 5, pp. 2557-63, 2003

Images

Product Details anti-BMP7 Antibody Target Details BMP7 Application Details Handling References for anti-BMP7 antibody (ABIN357185) back to top
Supplier Images
 image for anti-Bone Morphogenetic Protein 7 (BMP7) (N-Term) antibody (ABIN357185) anti-Bone Morphogenetic Protein 7 (BMP7) (N-Term) antibody
 image for anti-Bone Morphogenetic Protein 7 (BMP7) (N-Term) antibody (ABIN357185) anti-Bone Morphogenetic Protein 7 (BMP7) (N-Term) antibody (Image 2)
 image for anti-Bone Morphogenetic Protein 7 (BMP7) (N-Term) antibody (ABIN357185) anti-Bone Morphogenetic Protein 7 (BMP7) (N-Term) antibody (Image 3)