TINF2 Products
(TERF1 Interacting Nuclear Factor 2 (TIN2))
Categories
This gene encodes one of the proteins of the shelterin, or telosome, complex which protects telomeres by allowing the cell to distinguish between telomeres and regions of DNA damage. The protein encoded by this gene is a critical part of shelterin\; it interacts with the three DNA-binding proteins of the shelterin complex, and it is important for assembly of the complex. Mutations in this gene cause dyskeratosis congenita (DKC), an inherited bone marrow failure syndrome. [provided by RefSeq, Mar 2010].
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Featured TINF2 Categories
TINF2 Antibodies
High quality antibodies with extensive validation data.
TINF2 ELISA Kits
Reliable ELISA kits for a wide range of species.
TINF2 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended TINF2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IF, ICC
Validations
- (4)
Cat. No.
ABIN6265586
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse, Rat
Application
WB, IHC, IF
Validations
- (2)
Cat. No.
ABIN7075860
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (2)
Cat. No.
ABIN525684
Quantity
50 μg
Datasheet
Datasheet
Recommended TINF2 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6960008
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN4973357
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Validations
Cat. No.
ABIN1161186
Quantity
96 tests
Datasheet
Datasheet
Recommended TINF2 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1322805
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Insect Cells
Validations
- (1)
Cat. No.
ABIN3130450
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Human
Source
Insect Cells
Validations
- (1)
Cat. No.
ABIN3074172
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our TINF2 products
: "The Shelterin TIN2 Subunit Mediates Recruitment of Telomerase to Telomeres." in: PLoS genetics, Vol. 11, Issue 7, pp. e1005410, (2015) (PubMed).: "Telomere dysfunction and activation of alternative lengthening of telomeres in B-lymphocytes infected by Epstein-Barr virus." in: Oncogene, Vol. 32, Issue 49, pp. 5522-30, (2013) (PubMed).
: "DNA damage accumulation and TRF2 degradation in atypical Werner syndrome fibroblasts with LMNA mutations." in: Frontiers in genetics, Vol. 4, pp. 129, (2013) (PubMed).
: "Characterization of the DNA binding specificity of Shelterin complexes." in: Nucleic acids research, Vol. 39, Issue 21, pp. 9206-23, (2011) (PubMed).
: "The Epstein-Barr virus nuclear antigen-1 promotes telomere dysfunction via induction of oxidative stress." in: Leukemia, Vol. 25, Issue 6, pp. 1017-25, (2011) (PubMed).
: "Spontaneous occurrence of telomeric DNA damage response in the absence of chromosome fusions." in: Nature structural & molecular biology, Vol. 16, Issue 12, pp. 1244-51, (2009) (PubMed).
: "Identification of candidate alternative lengthening of telomeres genes by methionine restriction and RNA interference." in: Oncogene, Vol. 26, Issue 32, pp. 4635-47, (2007) (PubMed).
: "Human fetal ovarian culture permits meiotic progression and chromosome pairing process." in: Human reproduction (Oxford, England), Vol. 21, Issue 6, pp. 1359-67, (2006) (PubMed).
: "Chromosome 18 pairing behavior in human trisomic oocytes. Presence of an extra chromosome extends bouquet stage." in: Reproduction (Cambridge, England), Vol. 129, Issue 5, pp. 565-75, (2005) (PubMed).
: "Female-specific features of recombinational double-stranded DNA repair in relation to synapsis and telomere dynamics in human oocytes." in: Chromosoma, Vol. 113, Issue 1, pp. 22-33, (2004) (PubMed).
Synonyms and alternative names related to TINF2
TERF1 interacting nuclear factor 2 (TINF2), Terf1 (TRF1)-interacting nuclear factor 2 (Tinf2), AW552114, D14Wsu146e, DKCA3, TIN2, Tin2Protein level used designations for TINF2
- TERF1-interacting nuclear factor 2
- TRF1-interacting nuclear protein 2
- TRF1-interacting nuclear factor 2
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