anti-Human TLR6 antibody for Intracellular Flow Cytometry

Recommended TLR6 Antibody (supplied by: Log in to see )

Antigen
Toll-Like Receptor 6 (TLR6) Antibodies
  • TLR1
  • TLR16
  • CD286
  • TLR-6
  • toll-like receptor 1 family member A
  • toll like receptor 6
  • toll-like receptor 6
  • TLR1A
  • TLR6
  • Tlr6
Reactivity
Human
192
68
10
3
3
2
1
1
Host
Mouse
132
73
14
Clonality
Monoclonal
Conjugate
This TLR6 antibody is conjugated to PE
19
17
12
7
7
5
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Application
Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunofluorescence (IF), Intracellular Flow Cytometry (ICFC), Immunoprecipitation (IP), Immunohistochemistry (IHC), Western Blotting (WB)
118
97
82
82
54
21
15
15
6
5
5
2
1
1
1
1
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Catalog No. ABIN2663315
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN2663316 ICC FACS IF ICFC IP IHC WB PE Mouse IgG1 kappa Log in to see TLR6-127 4

General

Antigen Toll-Like Receptor 6 (TLR6) Antibodies
Reactivity Human
(192), (68), (10), (3), (3), (2), (1), (1)
Host Mouse
(132), (73), (14)
Clonality (Clone)
Monoclonal   ( )
Conjugate This TLR6 antibody is conjugated to PE
(19), (17), (12), (7), (7), (5), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunofluorescence (IF), Intracellular Flow Cytometry (ICFC), Immunoprecipitation (IP), Immunohistochemistry (IHC), Western Blotting (WB)
(118), (97), (82), (82), (54), (21), (15), (15), (6), (5), (5), (2), (1), (1), (1), (1)
Pubmed 4 references available
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Product Details anti-TLR6 Antibody

Target Details TLR6 Application Details Handling References for anti-TLR6 antibody (ABIN2663315) Images
Purification The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
Clone TLR6-127
Isotype IgG1 kappa
Plasmids, Primers & others

Target Details TLR6

Product Details anti-TLR6 Antibody Application Details Handling References for anti-TLR6 antibody (ABIN2663315) Images back to top
Antigen
Alternative Name CD286 (TLR6 Antibody Abstract)
Background Toll-like receptors (TLRs) are type I transmembrane signaling receptors characterized by containing leucine-rich repeats (LRR) extracellular domain and IL-1 receptor like intracellular domain. TLRs are responsible for recognizing pathogen-associated molecule patterns (PAMPs). They are primary sensors of both innate and adaptive immune systems. To date a total of 12 TLRs have been identified. Toll-like receptor 6 (TLR6), known as CD286, is one of the important receptors. TLR6 is colocalized with TLR2 on the cell surface of monocytes/macrophages, dendritic cells, granulocytes. The TLR2/TLR6 complex plays a role in the innate immune response to diacylated lipoprotein and peptidoglycan antigens.
Pathways TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades

Application Details

Product Details anti-TLR6 Antibody Target Details TLR6 Handling References for anti-TLR6 antibody (ABIN2663315) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-TLR6 Antibody Target Details TLR6 Application Details References for anti-TLR6 antibody (ABIN2663315) Images back to top
Buffer Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Protect from prolonged exposure to light. Do not freeze.
Storage 4 °C
Storage Comment The antibody solution should be stored undiluted between 2°C and 8°C.

References for anti-TLR6 antibody (ABIN2663315)

Product Details anti-TLR6 Antibody Target Details TLR6 Application Details Handling Images back to top
Background publications

Shimizu, Kida, Kuwano: "A dipalmitoylated lipoprotein from Mycoplasma pneumoniae activates NF-kappa B through TLR1, TLR2, and TLR6." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 175, Issue 7, pp. 4641-6, 2005

Nakao, Funami, Kikkawa, Taniguchi, Nishiguchi, Fukumori, Seya, Matsumoto: "Surface-expressed TLR6 participates in the recognition of diacylated lipopeptide and peptidoglycan in human cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 174, Issue 3, pp. 1566-73, 2005

Into, Kiura, Yasuda, Kataoka, Inoue, Hasebe, Takeda, Akira, Shibata: "Stimulation of human Toll-like receptor (TLR) 2 and TLR6 with membrane lipoproteins of Mycoplasma fermentans induces apoptotic cell death after NF-kappa B activation." in: Cellular microbiology, Vol. 6, Issue 2, pp. 187-99, 2004

Takeuchi, Kawai, Mühlradt, Morr, Radolf, Zychlinsky, Takeda, Akira: "Discrimination of bacterial lipoproteins by Toll-like receptor 6." in: International immunology, Vol. 13, Issue 7, pp. 933-40, 2001

Images

Product Details anti-TLR6 Antibody Target Details TLR6 Application Details Handling References for anti-TLR6 antibody (ABIN2663315) back to top
Supplier Images
Flow Cytometry (FACS) image for anti-Toll-Like Receptor 6 (TLR6) antibody (PE) (ABIN2663315) anti-Toll-Like Receptor 6 (TLR6) antibody (PE)