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anti-SIGIRR Antibodies

43 Single Immunoglobulin and Toll-Interleukin 1 Receptor (TIR) Domain (SIGIRR) Antibodies from 12 manufacturers are available on www.antibodies-online.com.

43 results:

anti-SIGIRR antibody (Single Immunoglobulin and Toll-Interleukin 1 Receptor (TIR) Domain) (AA 1-118) Primary Antibody

SIGIRR Reactivity: Human ICC, IHC, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1171735
$270.00
Plus shipping costs $45.00
100 μL (More quantities available)
local_shipping Shipping to: United States
Delivery in 12 to 15 Business Days

anti-SIGIRR antibody (Single Immunoglobulin and Toll-Interleukin 1 Receptor (TIR) Domain) (AA 1-118) Primary Antibody

SIGIRR Reactivity: Rat ICC, IHC, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1171738
$292.00
Plus shipping costs $45.00
100 μL (More quantities available)
local_shipping Shipping to: United States
Delivery in 12 to 15 Business Days

anti-SIGIRR antibody (Single Immunoglobulin and Toll-Interleukin 1 Receptor (TIR) Domain) (C-Term) Primary Antibody

SIGIRR Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Zebrafish (Danio rerio) IHC, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2783841
$389.00
Plus shipping costs $45.00
100 μL
local_shipping Shipping to: United States
Delivery in 2 to 3 Business Days

anti-SIGIRR antibody (Single Immunoglobulin and Toll-Interleukin 1 Receptor (TIR) Domain) Primary Antibody

SIGIRR Reactivity: Human ICC, WB Host: Rabbit Polyclonal unconjugated
Pubmed 2
Catalog No. ABIN541239
$542.86
Plus shipping costs $45.00
100 μg
local_shipping Shipping to: United States
Delivery in 11 to 12 Business Days

anti-SIGIRR antibody (Single Immunoglobulin and Toll-Interleukin 1 Receptor (TIR) Domain) (Center) Primary Antibody

SIGIRR Reactivity: Human IHC (fro), IHC (p), WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2856102
$509.08
Plus shipping costs $45.00
100 μL
local_shipping Shipping to: United States
Delivery in 3 to 4 Business Days

anti-SIGIRR antibody (Single Immunoglobulin and Toll-Interleukin 1 Receptor (TIR) Domain) (AA 1-117) Primary Antibody

SIGIRR Reactivity: Mouse ICC, IHC, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1860550
$277.00
Plus shipping costs $45.00
100 μL (More quantities available)
local_shipping Shipping to: United States
Delivery in 10 to 13 Business Days

anti-SIGIRR antibody (Single Immunoglobulin and Toll-Interleukin 1 Receptor (TIR) Domain) (C-Term) Primary Antibody

SIGIRR Reactivity: Human ELISA, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6655986
$379.00
Plus shipping costs $45.00 and $24.00 dry ice
100 μg
local_shipping Shipping to: United States
Delivery in 1 to 2 Business Days

anti-SIGIRR antibody (Single Immunoglobulin and Toll-Interleukin 1 Receptor (TIR) Domain) (C-Term) Primary Antibody

SIGIRR Reactivity: Human, Mouse ICC, ELISA, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1030659
$380.00
Plus shipping costs $45.00
0.1 mg (More quantities available)
local_shipping Shipping to: United States
Delivery in 2 to 3 Business Days

anti-SIGIRR antibody (Single Immunoglobulin and Toll-Interleukin 1 Receptor (TIR) Domain) (AA 1-410) Primary Antibody

SIGIRR Reactivity: Human IP, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN528391
$425.71
Plus shipping costs $45.00
100 μL
local_shipping Shipping to: United States
Delivery in 11 to 12 Business Days

anti-SIGIRR antibody (Single Immunoglobulin and Toll-Interleukin 1 Receptor (TIR) Domain) (AA 1-410) Primary Antibody

SIGIRR Reactivity: Human ELISA, WB Host: Mouse Monoclonal 3H8-2G3 unconjugated
Catalog No. ABIN528393
$440.00
Plus shipping costs $45.00
200 μL
local_shipping Shipping to: United States
Delivery in 11 to 12 Business Days
  • Type Primary
    • Primary
  • Target Single Immunoglobulin and Toll-Interleukin 1 Receptor (TIR) Domain (SIGIRR)
    • Single Immunoglobulin and Toll-Interleukin 1 Receptor (TIR) Domain (SIGIRR)
    • Histone 3 (H3)
    • Epidermal Growth Factor Receptor (EGFR)
    • Tumor Protein P53 (TP53)
    • Mast/stem Cell Growth Factor Receptor (KIT)
    • Protein tyrosine Phosphatase, Receptor Type, C (PTPRC)
    • CD4 Molecule (CD4)
    • tau Protein
    • Tumor Necrosis Factor alpha (TNF)
    • Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2)
    • V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1)
    • Interferon gamma (IFNG)
    • BCL2-Associated Agonist of Cell Death (BAD)
    • Estrogen Receptor 1 (ESR1)
    • Nuclear Factor-KB P65 (NFkBP65)
    • Albumin (ALB)
    • V-Raf-1 Murine Leukemia Viral Oncogene Homolog 1 (RAF1)
    • B-Cell CLL/lymphoma 2 (BCL2)
    • Tuberous Sclerosis 2 (TSC2)
    • CD19 Molecule (CD19)
    • CD44
    • Amyloid beta (A4) Precursor Protein (APP)
    • CD8a Molecule (CD8A)
    • Hemagglutinin (HA)
    • Platelet/endothelial Cell Adhesion Molecule (PECAM1)
    • Myc Proto-Oncogene protein (MYC)
    • CD3e Molecule, epsilon (CD3-TCR Complex) (CD3E)
    • Integrin alpha M (ITGAM)
    • CD8
    • Histone H4
    • Jun Proto-Oncogene (JUN)
    • Interleukin 6 (IL6)
    • Vimentin (VIM)
    • C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1)
    • Epithelial Cell Adhesion Molecule (EPCAM)
    • Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 (RPS6KB1)
    • Interleukin 2 Receptor, alpha (IL2RA)
    • CD5 Molecule (CD5)
    • Interleukin 2 (IL2)
    • PTK2 Protein tyrosine Kinase 2 (PTK2)
    • Tuberous Sclerosis 1 (TSC1)
    • CD3
    • Synuclein, alpha (SNCA)
    • Glial Fibrillary Acidic Protein (GFAP)
    • Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1)
    • Androgen Receptor (AR)
    • CD14
    • Mucin 1, Cell Surface Associated (MUC1)
    • Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase) (KDR)
    • Cyclin-Dependent Kinase 1 (CDK1)
    • CD34
  • Application
    • Western Blotting (WB)
    • ELISA
    • Immunohistochemistry (IHC)
    • Immunocytochemistry (ICC)
    • Flow Cytometry (FACS)
    • Immunohistochemistry (Frozen Sections) (IHC (fro))
    • Immunochromatography (IC)
    • Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    • Immunoprecipitation (IP)
    • Immunofluorescence (fixed cells) (IF/ICC)
    • Enzyme Immunoassay (EIA)
    • Immunofluorescence (IF)
  • Reactivity
    • Human
    • Mouse
    • Rat
    • Cow
    • Dog
    • Guinea Pig
    • Horse
    • Zebrafish (Danio rerio)
    • Monkey
    • Pig
  • Cited in publications
  • Images available
  • Host
    • Rabbit
    • Mouse
    • Rat
  • Clonality
    • Polyclonal
    • Monoclonal
  • Clone
    • 010
    • 3H8-2G3
    • 016
    • 10K61
    • 612201
    • MM0547-10D5
    • RM0325-2M39
  • Binding Specificity
    • AA 1-118
    • C-Term
    • AA 1-410
    • AA 1-117
    • AA 309-323
    • AA 334-358
    • AA 1-120
    • AA 1-411
    • AA 380-393
    • Center
  • Conjugate
    • Un-conjugated
    • Biotin
    • APC
    • PE
  • Isotype
    • IgG
    • IgG2a
    • IgM kappa
    • IgG1
    • IgG2
  • Format
    • Liquid
    • Lyophilized

SIGIRR Antigen Profile

Protein Summary

Acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways. Attenuates the recruitment of receptor-proximal signaling components to the TLR4 receptor, probably through an TIR-TIR domain interaction with TLR4. Through its extracellular domain interferes with the heterodimerization of Il1R1 and IL1RAP (By similarity).

Alternative names and synonyms associated with SIGIRR

  • single Ig and TIR domain containing (SIGIRR) antibody
  • single immunoglobulin and toll-interleukin 1 receptor (TIR) domain (Sigirr) antibody
  • single immunoglobulin and toll-interleukin 1 receptor (TIR) domain (sigirr) antibody
  • single Ig and TIR domain containing (Sigirr) antibody
  • AI256711 antibody
  • RGD1306732 antibody
  • sc:d148 antibody
  • TIR8 antibody

Protein level used designations for SIGIRR

single Ig IL-1-related receptor , single Ig IL-1R-related molecule , single immunoglobulin domain IL1R1 related , single immunoglobulin domain-containing IL1R-related protein , toll/interleukin-1 receptor 8 , single Ig IL-1 receptor related protein , single Ig IL-1R-related protein , TIR8

GENE ID SPECIES
59307 Homo sapiens
24058 Mus musculus
563606 Danio rerio
422995 Gallus gallus
531801 Bos taurus
309106 Rattus norvegicus

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