Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

anti-SIGIRR Antibodies

41 results:

anti-SIGIRR antibody (Single Immunoglobulin and Toll-Interleukin 1 Receptor (TIR) Domain) (C-Term) Primary Antibody

SIGIRR Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Zebrafish (Danio rerio) IHC, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2783841
$389.00
Plus shipping costs $45.00
100 μL
local_shipping Shipping to: United States
Delivery in 2 to 3 Business Days

anti-SIGIRR antibody (Single Immunoglobulin and Toll-Interleukin 1 Receptor (TIR) Domain) (Center) Primary Antibody

SIGIRR Reactivity: Human IHC (fro), IHC (p), WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2856102
$509.08
Plus shipping costs $45.00
100 μL
local_shipping Shipping to: United States
Delivery in 3 to 4 Business Days

anti-SIGIRR antibody (Single Immunoglobulin and Toll-Interleukin 1 Receptor (TIR) Domain) (C-Term) Primary Antibody

SIGIRR Reactivity: Human ELISA, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6655986
$379.00
Plus shipping costs $45.00 and $24.00 dry ice
100 μg
local_shipping Shipping to: United States
Delivery in 1 to 2 Business Days

anti-SIGIRR antibody (Single Immunoglobulin and Toll-Interleukin 1 Receptor (TIR) Domain) (C-Term) Primary Antibody

SIGIRR Reactivity: Human, Mouse ICC, ELISA, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1030659
$380.00
Plus shipping costs $45.00
0.1 mg (More quantities available)
local_shipping Shipping to: United States
Delivery in 2 to 3 Business Days

anti-SIGIRR antibody (Single Immunoglobulin and Toll-Interleukin 1 Receptor (TIR) Domain) (C-Term) Primary Antibody

SIGIRR Reactivity: Human, Mouse EIA, IF, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN500712
$511.50
Plus shipping costs $45.00
0.1 mg
local_shipping Shipping to: United States
Delivery in 6 to 8 Business Days

anti-SIGIRR antibody (Single Immunoglobulin and Toll-Interleukin 1 Receptor (TIR) Domain) (AA 1-410) Primary Antibody

SIGIRR Reactivity: Human IP, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN528391
$585.71
Plus shipping costs $45.00
100 μL
local_shipping Shipping to: United States
Delivery in 11 to 12 Business Days

anti-SIGIRR antibody (Single Immunoglobulin and Toll-Interleukin 1 Receptor (TIR) Domain) (AA 1-410) Primary Antibody

SIGIRR Reactivity: Human ELISA, WB Host: Mouse Monoclonal 3H8-2G3 unconjugated
Catalog No. ABIN528393
$600.00
Plus shipping costs $45.00
200 μL
local_shipping Shipping to: United States
Delivery in 11 to 12 Business Days

anti-SIGIRR antibody (Single Immunoglobulin and Toll-Interleukin 1 Receptor (TIR) Domain) (C-Term) Primary Antibody

SIGIRR Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Monkey, Zebrafish (Danio rerio) IHC, IHC (p), WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6747128
$727.83
Plus shipping costs $45.00
100 μL
local_shipping Shipping to: United States
Delivery in 11 to 14 Business Days

anti-SIGIRR antibody (Single Immunoglobulin and Toll-Interleukin 1 Receptor (TIR) Domain) (C-Term) Primary Antibody

SIGIRR Reactivity: Human, Mouse IHC (fro), WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2476475
$221.29
Plus shipping costs $45.00
50 μg (More quantities available)
local_shipping Shipping to: United States
Delivery in 3 to 4 Business Days

anti-SIGIRR antibody (Single Immunoglobulin and Toll-Interleukin 1 Receptor (TIR) Domain) (AA 1-118) Primary Antibody

SIGIRR Reactivity: Human FACS Host: Rabbit Monoclonal 010 unconjugated
Catalog No. ABIN6923784
$359.41
Plus shipping costs $45.00
100 μL (More quantities available)
local_shipping Shipping to: United States
Delivery in 11 to 13 Business Days
  • Type Primary
    • Primary
  • Target Single Immunoglobulin and Toll-Interleukin 1 Receptor (TIR) Domain (SIGIRR)
    • Single Immunoglobulin and Toll-Interleukin 1 Receptor (TIR) Domain (SIGIRR)
    • Histone 3 (H3)
    • Tumor Protein P53 (TP53)
    • Epidermal Growth Factor Receptor (EGFR)
    • Mast/stem Cell Growth Factor Receptor (KIT)
    • Protein tyrosine Phosphatase, Receptor Type, C (PTPRC)
    • CD4
    • tau Protein
    • Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2)
    • Tumor Necrosis Factor alpha (TNF alpha)
    • V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1)
    • Interferon gamma (IFNG)
    • Nuclear Factor-kB p65 (NFkBP65)
    • Estrogen Receptor 1 (ESR1)
    • Albumin (ALB)
    • BCL2-Associated Agonist of Cell Death (BAD)
    • B-Cell CLL/lymphoma 2 (BCL2)
    • V-Raf-1 Murine Leukemia Viral Oncogene Homolog 1 (RAF1)
    • CD8a Molecule (CD8A)
    • Platelet/endothelial Cell Adhesion Molecule (PECAM1)
    • Tuberous Sclerosis 2 (TSC2)
    • CD19 Molecule (CD19)
    • CD3 epsilon (CD3E)
    • Hemagglutinin (HA)
    • Integrin alpha M (ITGAM)
    • CD8
    • Histone H4
    • CD44
    • Jun Proto-Oncogene (JUN)
    • Interleukin 6 (IL6)
    • Epithelial Cell Adhesion Molecule (EPCAM)
    • Myc Proto-Oncogene protein (MYC)
    • Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 (RPS6KB1)
    • Interleukin 2 Receptor, alpha (IL2RA)
    • Catenin, beta (CATNB)
    • CD5
    • Vimentin (VIM)
    • Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1)
    • Mucin 1 (MUC1)
    • CD3
    • PTK2 Protein tyrosine Kinase 2 (PTK2)
    • Glial Fibrillary Acidic Protein (GFAP)
    • C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1)
    • CD34
    • Interleukin 2 (IL2)
    • Insulin Receptor Substrate 1 (IRS1)
    • Keratin 18 (KRT18)
    • Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase) (KDR)
    • Amyloid beta (A4) Precursor Protein (APP)
    • CD14
    • Tuberous Sclerosis 1 (TSC1)
  • Application
    • Western Blotting (WB)
    • ELISA
    • Immunohistochemistry (IHC)
    • Immunocytochemistry (ICC)
    • Immunoprecipitation (IP)
    • Flow Cytometry (FACS)
    • Immunochromatography (IC)
    • Immunohistochemistry (Frozen Sections) (IHC (fro))
    • Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    • Immunofluorescence (fixed cells) (IF/ICC)
    • Enzyme Immunoassay (EIA)
    • Immunofluorescence (IF)
  • Reactivity
    • Human
    • Mouse
    • Rat
    • Cow
    • Dog
    • Guinea Pig
    • Horse
    • Zebrafish (Danio rerio)
    • Monkey
    • Pig
  • Images available
  • Preservative free only
  • Host
    • Rabbit
    • Mouse
    • Rat
  • Clonality
    • Polyclonal
    • Monoclonal
  • Clone
    • 010
    • 3H8-2G3
    • 016
    • 10K61
    • 612201
    • MM0547-10D5
    • RM0325-2M39
  • Binding Specificity
    • AA 1-118
    • C-Term
    • AA 1-410
    • AA 1-117
    • AA 309-323
    • AA 334-358
    • AA 1-120
    • AA 1-411
    • AA 380-393
    • Center
  • Conjugate
    • Un-conjugated
    • Biotin
    • APC
    • PE
  • Isotype
    • IgG
    • IgG2a
    • IgM kappa
    • IgG1
    • IgG2
  • Format
    • Liquid
    • Lyophilized

SIGIRR Antigen Profile

Protein Summary

Acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways. Attenuates the recruitment of receptor-proximal signaling components to the TLR4 receptor, probably through an TIR-TIR domain interaction with TLR4. Through its extracellular domain interferes with the heterodimerization of Il1R1 and IL1RAP (By similarity).

Alternative names and synonyms associated with SIGIRR

  • single Ig and TIR domain containing (SIGIRR) antibody
  • single immunoglobulin and toll-interleukin 1 receptor (TIR) domain (Sigirr) antibody
  • single immunoglobulin and toll-interleukin 1 receptor (TIR) domain (sigirr) antibody
  • single Ig and TIR domain containing (Sigirr) antibody
  • AI256711 antibody
  • RGD1306732 antibody
  • sc:d148 antibody
  • TIR8 antibody

Protein level used designations for SIGIRR

single Ig IL-1-related receptor , single Ig IL-1R-related molecule , single immunoglobulin domain IL1R1 related , single immunoglobulin domain-containing IL1R-related protein , toll/interleukin-1 receptor 8 , single Ig IL-1 receptor related protein , single Ig IL-1R-related protein , TIR8

GENE ID SPECIES
59307 Homo sapiens
24058 Mus musculus
563606 Danio rerio
422995 Gallus gallus
531801 Bos taurus
309106 Rattus norvegicus

Did you look for something else?

You are here:
help Support