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TRP63 Products

(Transformation Related Protein 63 (TRP63))

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This gene encodes tumor protein p63, a member of the p53 family of transcription factors involved in cellular responses to stress and development. The family members include tumor proteins p53, p63, and p73, which have high sequence similarity to one another. This similarity allows p63 and p73 to transactivate p53-responsive genes causing cell cycle arrest and apoptosis. The family members can interact with each other in many ways, including direct and indirect protein interactions. This results in mutual regulation of target gene promoters. Tumor protein p63 -/- mice have several developmental defects which include the lack of limbs and other tissues, such as teeth and mammary glands, which develop as a result of interactions between mesenchyme and epithelium. Both alternative splicing and the use of alternative promoters result in multiple transcript variants encoding different protein isoforms.[provided by RefSeq, Dec 2009].

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Featured TRP63 Categories

TRP63 Antibodies

High quality antibodies with extensive validation data.

Recommended TRP63 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA
Validations
Cat. No. ABIN1019670
Quantity 100 μg
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish (Danio rerio)
Application WB
Validations
  • (1)
Cat. No. ABIN2778222
Quantity 100 μL
Datasheet Datasheet

Synonyms and alternative names related to TRP63

transformation related protein 63 (Trp63), AI462811, Ket, P51/P63, P63, P73l, Tp63, Trp53rp1

Protein level used designations for TRP63

  • transformation-related protein 63
  • tumor protein 63
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