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TXNIP Products

(Thioredoxin Interacting Protein (TXNIP))
regulates thioredoxin to play an important role in the preservation of cellular viability [RGD, Feb 2006].

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Featured TXNIP Categories

TXNIP Antibodies

High quality antibodies with extensive validation data.

TXNIP ELISA Kits

Reliable ELISA kits for a wide range of species.

TXNIP Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended TXNIP Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (8)
Cat. No. ABIN7433201
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (1)
  • (5)
Cat. No. ABIN6149733
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (5)
Cat. No. ABIN7433198
Quantity 100 μL
Datasheet Datasheet

Recommended TXNIP ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (2)
  • (1)
Cat. No. ABIN6959907
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6959908
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6975747
Quantity 96 tests
Datasheet Datasheet

Recommended TXNIP Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7125361
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1324240
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
Cat. No. ABIN3096116
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our TXNIP products

Oberacker, Fritz, Schanz, Alscher, Ketteler, Schricker: "Enhanced Oxidative DNA-Damage in Peritoneal Dialysis Patients via the TXNIP/TRX Axis." in: Antioxidants (Basel, Switzerland), Vol. 11, Issue 6, (2022) (PubMed).

An, Zhang, Cao, Chen, Qin, Yang: "Punicalagin Protects Diabetic Nephropathy by Inhibiting Pyroptosis Based on TXNIP/NLRP3 Pathway." in: Nutrients, Vol. 12, Issue 5, (2021) (PubMed).

Yuan, Tan, Rajamani, Solly, King, Lecce, Simpson, Lam, Jenkins, Bursill, Keech, Ng: "Fenofibrate Rescues Diabetes-Related Impairment of Ischemia-Mediated Angiogenesis by PPARα-Independent Modulation of Thioredoxin-Interacting Protein." in: Diabetes, Vol. 68, Issue 5, pp. 1040-1053, (2019) (PubMed).

Macer-Wright, Sileikaite, Rayner, Hawkins: "8-Chloroadenosine Alters the Metabolic Profile and Downregulates Antioxidant and DNA Damage Repair Pathways in Macrophages." in: Chemical research in toxicology, (2019) (PubMed).

Zaragoza-Campillo, Morán: "Reactive Oxygen Species Evoked by Potassium Deprivation and Staurosporine Inactivate Akt and Induce the Expression of TXNIP in Cerebellar Granule Neurons." in: Oxidative medicine and cellular longevity, Vol. 2017, pp. 8930406, (2017) (PubMed).

Liu, Sun, Wang, Zhang, Zhao, Zhao: "Silymarin attenuated paraquat-induced cytotoxicity in macrophage by regulating Trx/TXNIP complex, inhibiting NLRP3 inflammasome activation and apoptosis." in: Toxicology in vitro : an international journal published in association with BIBRA, Vol. 46, pp. 265-272, (2017) (PubMed).

Li, Kover, Heruth, Watkins, Guo, Moore, He, Zang, Clements, Yan: "Thioredoxin-interacting protein promotes high-glucose-induced macrovascular endothelial dysfunction." in: Biochemical and biophysical research communications, Vol. 493, Issue 1, pp. 291-297, (2017) (PubMed).

Zhang, Zhang, Deng, Zhang, Xu: "Baicalin protects AML-12 cells from lipotoxicity via the suppression of ER stress and TXNIP/NLRP3 inflammasome activation." in: Chemico-biological interactions, Vol. 278, pp. 189-196, (2017) (PubMed).

Lee, Lee, Bae, Kang, Kim: "Genome-wide identification of target genes for miR-204 and miR-211 identifies their proliferation stimulatory role in breast cancer cells." in: Scientific reports, Vol. 6, pp. 25287, (2016) (PubMed).

Li, Shen, Sun, Li, Sun, Liu, Zhang, Huang, Meng, Li: "MicroRNA-20a negatively regulates expression of NLRP3-inflammasome by targeting TXNIP in adjuvant-induced arthritis fibroblast-like synoviocytes." in: Joint, bone, spine : revue du rhumatisme, Vol. 83, Issue 6, pp. 695-700, (2016) (PubMed).

Synonyms and alternative names related to TXNIP

thioredoxin interacting protein (TXNIP), TATA box binding protein like 2 (Tbpl2), TATA-box binding protein like 2 (TBPL2), thioredoxin interacting protein (Txnip), thioredoxin interacting protein L homeolog (txnip.L), thioredoxin interacting protein (txnip), thioredoxin interacting protein a (txnipa), 1200008J08Rik, AA682105, EST01027, Gm348, HHCPA78, Hyplip1, sb:cb368, Tbp-2, TBP2, THIF, Trf3, TRF3, txnip, VDUP1, Vdup1

Protein level used designations for TXNIP

  • thioredoxin binding protein 2
  • thioredoxin-binding protein 2
  • thioredoxin-interacting protein
  • upregulated by 1,25-dihydroxyvitamin D-3
  • vitamin D3 up-regulated protein 1
  • TATA box binding protein-like 2
  • TATA box-binding protein-like protein 2
  • TATA box-binding protein-related factor 3
  • TBP-like protein 2
  • TBP-related factor 3 (Trf3)
  • TBP-related factor 3
  • hyperlipidemia 1
  • thioredoxin binding protein-2
  • thioredoxin interacting protein
  • Thioredoxin-interacting protein
  • thioredoxin interacting protein a
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