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Ubiquitin-Conjugating Enzyme E2N Products

(Ubiquitin-Conjugating Enzyme E2N (UBE2N))
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. Studies in mouse suggest that this protein plays a role in DNA postreplication repair. [provided by RefSeq, Jul 2008].

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Featured Ubiquitin-Conjugating Enzyme E2N Categories

Ubiquitin-Conjugating Enzyme E2N Antibodies

High quality antibodies with extensive validation data.

Ubiquitin-Conjugating Enzyme E2N Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Ubiquitin-Conjugating Enzyme E2N Antibodies

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Reactivity Human
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Cat. No. ABIN563325
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Reactivity Human
Application WB, IHC, IF
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Cat. No. ABIN7271179
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Cat. No. ABIN2777765
Quantity 100 μL
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Recommended Ubiquitin-Conjugating Enzyme E2N Proteins

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Reactivity Human
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Cat. No. ABIN7125624
Quantity 50 μg
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Reactivity Human
Source Escherichia coli (E. coli)
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Cat. No. ABIN7125625
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Reactivity Human
Source Escherichia coli (E. coli)
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Cat. No. ABIN666632
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Latest Publications for our Ubiquitin-Conjugating Enzyme E2N products

Shaw, Wang, Brown, Chávez, Reif, Smith, Scott, McClure, Boradia, Hammond, Sundberg, Snyder, Liu, DePonte, Villar, Ueti, de la Fuente, Ernst, Pal, Fikrig, Pedra: "Infection-derived lipids elicit an immune deficiency circuit in arthropods." in: Nature communications, Vol. 8, pp. 14401, (2017) (PubMed).

Bonora, Wieckowsk, Chinopoulos, Kepp, Kroemer, Galluzzi, Pinton: "Molecular mechanisms of cell death: central implication of ATP synthase in mitochondrial permeability transition." in: Oncogene, Vol. 34, Issue 12, pp. 1608, (2015) (PubMed).

Masuda, Suzuki, Kawai, Hishiki, Hashimoto, Masutani, Hishida, Suzuki, Kamiya: "En bloc transfer of polyubiquitin chains to PCNA in vitro is mediated by two different human E2-E3 pairs." in: Nucleic acids research, Vol. 40, Issue 20, pp. 10394-407, (2012) (PubMed).

Xu, Yan, Jovanovic, An, Cheng, Aakre, Yi, Eng, Link, Moses: "Quantitative analysis of the secretome of TGF-beta signaling-deficient mammary fibroblasts." in: Proteomics, Vol. 10, Issue 13, pp. 2458-70, (2010) (PubMed).

Stagg, Thomas, van den Boomen, Wiertz, Drabkin, Gemmill, Lehner: "The TRC8 E3 ligase ubiquitinates MHC class I molecules before dislocation from the ER." in: The Journal of cell biology, Vol. 186, Issue 5, pp. 685-92, (2009) (PubMed).

Zou, Papov, Malakhova, Kim, Dao, Li, Zhang: "ISG15 modification of ubiquitin E2 Ubc13 disrupts its ability to form thioester bond with ubiquitin." in: Biochemical and biophysical research communications, Vol. 336, Issue 1, pp. 61-8, (2005) (PubMed).

Pastushok, Moraes, Ellison, Xiao: "A single Mms2 "key" residue insertion into a Ubc13 pocket determines the interface specificity of a human Lys63 ubiquitin conjugation complex." in: The Journal of biological chemistry, Vol. 280, Issue 18, pp. 17891-900, (2005) (PubMed).

Zhang, Windheim, Roe, Peggie, Cohen, Prodromou, Pearl: "Chaperoned ubiquitylation--crystal structures of the CHIP U box E3 ubiquitin ligase and a CHIP-Ubc13-Uev1a complex." in: Molecular cell, Vol. 20, Issue 4, pp. 525-38, (2005) (PubMed).

Chen: "Ubiquitin signalling in the NF-kappaB pathway." in: Nature cell biology, Vol. 7, Issue 8, pp. 758-65, (2005) (PubMed).

Vogel, Fitzgerald, Fenton: "TLRs: differential adapter utilization by toll-like receptors mediates TLR-specific patterns of gene expression." in: Molecular interventions, Vol. 3, Issue 8, pp. 466-77, (2004) (PubMed).

Synonyms and alternative names related to Ubiquitin-Conjugating Enzyme E2N

ubiquitin conjugating enzyme E2 N (UBE2N), ubiquitin-conjugating enzyme E2N (Ube2n), ubiquitin conjugating enzyme E2 N S homeolog (ube2n.S), ubiquitin-conjugating enzyme E2Na (ube2na), ubiquitin-conjugating enzyme E2N (LOC100533434), ubiquitin conjugating enzyme E2 N (ube2n), ubiquitin-conjugating enzyme E2N (UBE2N), ubiquitin conjugating enzyme E2 N (Ube2n), ubiquitin-conjugating enzyme E2Nb (ube2nb), 1500026J17Rik, AL022654, BB101821, UBC13, ubc13, UbcH-ben, ubch-ben, UbcH13, ube2n, UBE2N, ube2nl, wu:fb11b03, wu:fc08b06, zgc:55726, zgc:63901

Protein level used designations for Ubiquitin-Conjugating Enzyme E2N

  • bendless-like ubiquitin conjugating enzyme
  • bendless-like ubiquitin-conjugating enzyme
  • ubiquitin carrier protein N
  • ubiquitin-conjugating enzyme E2 N
  • ubiquitin-conjugating enzyme E2N (UBC13 homolog, yeast)
  • ubiquitin-conjugating enzyme E2N (homologous to yeast UBC13)
  • ubiquitin-protein ligase N
  • yeast UBC13 homolog
  • bendless protein
  • ubiquitin-conjugating enzyme E2N (UBC13 homolog)
  • ube13a
  • ubiquitin-conjugating enzyme E2N
  • ubiquitin-conjugating enzyme e2 n
  • ubc13b
  • ubiquitin-conjugating enzyme E2Nb
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