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UCHL3 Products

(Ubiquitin Carboxyl-terminal Esterase L3 (Ubiquitin Thiolesterase) (Uchl3))
The protein encoded by this gene is a member of the deubiquitinating enzyme family. Members of this family are proteases that catalyze the removal of ubiquitin from polypeptides and are divided into five classes, depending on the mechanism of catalysis. This protein may hydrolyze the ubiquitinyl-N-epsilon amide bond of ubiquitinated proteins to regenerate ubiquitin for another catalytic cycle. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Aug 2012].

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Featured UCHL3 Categories

UCHL3 Antibodies

High quality antibodies with extensive validation data.

UCHL3 ELISA Kits

Reliable ELISA kits for a wide range of species.

UCHL3 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended UCHL3 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
  • (4)
  • (4)
Cat. No. ABIN1882147
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
  • (4)
Cat. No. ABIN563334
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ELISA
Validations
  • (5)
Cat. No. ABIN3029426
Quantity 0.4 mL
Datasheet Datasheet

Recommended UCHL3 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6951266
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN4884970
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Semi-Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6385075
Quantity 96 tests
Datasheet Datasheet

Recommended UCHL3 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1324515
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1324517
Quantity 10 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7321219
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our UCHL3 products

Wang, Yu, Hu, Cheng, Li: "Ubiquitin Carboxy-Terminal HydrolaseL3 Correlates with Human Sperm Count, Motility and Fertilization." in: PLoS ONE, Vol. 11, Issue 10, pp. e0165198, (2016) (PubMed).

Nogueira da Costa, Mijal, Keen, Findlay, Wild: "Proteomic analysis of the effects of the immunomodulatory mycotoxin deoxynivalenol." in: Proteomics, Vol. 11, Issue 10, pp. 1903-14, (2011) (PubMed).

Henderson, Vij, Zeitlin: "Ubiquitin C-terminal hydrolase-L1 protects cystic fibrosis transmembrane conductance regulator from early stages of proteasomal degradation." in: The Journal of biological chemistry, Vol. 285, Issue 15, pp. 11314-25, (2010) (PubMed).

Sun, Ying, Li, Shang, He, Chen, Cheng, Zhou: "Role of UCH-L1/ubiquitin in acute testicular ischemia-reperfusion injury." in: Biochemical and biophysical research communications, Vol. 366, Issue 2, pp. 539-44, (2008) (PubMed).

Kwon: "The new function of two ubiquitin C-terminal hydrolase isozymes as reciprocal modulators of germ cell apoptosis." in: Experimental animals / Japanese Association for Laboratory Animal Science, Vol. 56, Issue 2, pp. 71-7, (2007) (PubMed).

Sakurai, Ayukawa, Setsuie, Nishikawa, Hara, Ohashi, Nishimoto, Abe, Kudo, Sekiguchi, Sato, Aoki, Noda, Wada: "Ubiquitin C-terminal hydrolase L1 regulates the morphology of neural progenitor cells and modulates their differentiation." in: Journal of cell science, Vol. 119, Issue Pt 1, pp. 162-71, (2005) (PubMed).

Osaka, Wang, Takada, Takizawa, Setsuie, Li, Sato, Nishikawa, Sun, Sakurai, Harada, Hara, Kimura, Chiba, Namikawa, Kiyama, Noda, Aoki, Wada: "Ubiquitin carboxy-terminal hydrolase L1 binds to and stabilizes monoubiquitin in neuron." in: Human molecular genetics, Vol. 12, Issue 16, pp. 1945-58, (2003) (PubMed).

Saito, Iida, Sekine, Kawauchi, Higuchi, Ogawa, Nakamura: "Catalog of 680 variations among eight cytochrome p450 ( CYP) genes, nine esterase genes, and two other genes in the Japanese population." in: Journal of human genetics, Vol. 48, Issue 5, pp. 249-70, (2003) (PubMed).

Kurihara, Kikuchi, Wada, Tilghman: "Loss of Uch-L1 and Uch-L3 leads to neurodegeneration, posterior paralysis and dysphagia." in: Human molecular genetics, Vol. 10, Issue 18, pp. 1963-70, (2001) (PubMed).

Wilkinson, Lee, Deshpande, Duerksen-Hughes, Boss, Pohl: "The neuron-specific protein PGP 9.5 is a ubiquitin carboxyl-terminal hydrolase." in: Science (New York, N.Y.), Vol. 246, Issue 4930, pp. 670-3, (1989) (PubMed).

Synonyms and alternative names related to UCHL3

ubiquitin C-terminal hydrolase L3 (UCHL3), ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) (Uchl3), ubiquitin C-terminal hydrolase L3 (Uchl3), ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) (uchl3), ubiquitin C-terminal hydrolase L3 L homeolog (uchl3.L), ubiquitin C-terminal hydrolase L3 (uchl3), im:6908825, RGD1561196, UCH-6, UCH-L3, uchl4, zgc:109963

Protein level used designations for UCHL3

  • ubiquitin carboxyl-terminal hydrolase isozyme L3
  • ubiquitin thioesterase L3
  • ubiquitin thiolesterase
  • UCH-L3
  • ubiquitin carboxyl-terminal hydrolase-6
  • ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
  • ubiquitin carboxyl-terminal esterase L4
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