UCP1 Products
(Uncoupling Protein 1 (Mitochondrial, Proton Carrier) (UCP1))
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Mitochondrial uncoupling proteins (UCP) are members of the family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the three homologous protein domains of MACPs. This gene is expressed only in brown adipose tissue, a specialized tissue which functions to produce heat. [provided by RefSeq, Jul 2008].
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Featured UCP1 Categories
UCP1 Antibodies
High quality antibodies with extensive validation data.
UCP1 ELISA Kits
Reliable ELISA kits for a wide range of species.
UCP1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended UCP1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (7)
Cat. No.
ABIN6149883
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Rat
Application
WB, IHC, IP, ICC
Validations
- (5)
Cat. No.
ABIN7436078
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Goat, Human, Mouse, Rat
Application
WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro)
Validations
- (3)
- (4)
Cat. No.
ABIN675413
Quantity
100 μL
Datasheet
Datasheet
Recommended UCP1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6960371
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (3)
- (1)
Cat. No.
ABIN6960373
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6971066
Quantity
96 tests
Datasheet
Datasheet
Recommended UCP1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7125655
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1324534
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Insect Cells
Validations
- (1)
Cat. No.
ABIN3097080
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our UCP1 products
: "Diphyllin Improves High-Fat Diet-Induced Obesity in Mice Through Brown and Beige Adipocytes." in: Frontiers in endocrinology, Vol. 11, pp. 592818, (2021) (PubMed).: "Mature Human White Adipocytes Cultured under Membranes Maintain Identity, Function, and Can Transdifferentiate into Brown-like Adipocytes." in: Cell reports, Vol. 27, Issue 1, pp. 213-225.e5, (2019) (PubMed).
: "Differentiating SGBS adipocytes respond to PPARγ stimulation, irisin and BMP7 by functional browning and beige characteristics." in: Scientific reports, Vol. 9, Issue 1, pp. 5823, (2019) (PubMed).
: "Serum Amyloid P and a Dendritic Cell-Specific Intercellular Adhesion Molecule-3-Grabbing Nonintegrin Ligand Inhibit High-Fat Diet-Induced Adipose Tissue and Liver Inflammation and Steatosis in Mice." in: The American journal of pathology, Vol. 189, Issue 12, pp. 2400-2413, (2019) (PubMed).
: "IRX3 Promotes the Browning of White Adipocytes and Its Rare Variants are Associated with Human Obesity Risk." in: EBioMedicine, Vol. 24, pp. 64-75, (2018) (PubMed).
: "A Renewable Source of Human Beige Adipocytes for Development of Therapies to Treat Metabolic Syndrome." in: Cell reports, Vol. 25, Issue 11, pp. 3215-3228.e9, (2018) (PubMed).
: "Flow Cytometry of Mouse and Human Adipocytes for the Analysis of Browning and Cellular Heterogeneity." in: Cell reports, Vol. 24, Issue 10, pp. 2746-2756.e5, (2018) (PubMed).
: "The data on the aerobic training with or without calorie restriction and muscular levels of Irisin and muscular FNDC5 concentration in obese male Wistar rats." in: Data in brief, Vol. 21, pp. 888-892, (2018) (PubMed).
: "Pig has no uncoupling protein 1." in: Biochemical and biophysical research communications, Vol. 487, Issue 4, pp. 795-800, (2017) (PubMed).
: "Direct conversion of human fibroblasts to brown adipocytes by small chemical compounds." in: Scientific reports, Vol. 7, Issue 1, pp. 4304, (2017) (PubMed).
Synonyms and alternative names related to UCP1
plant uncoupling mitochondrial protein 1 (PUMP1), uncoupling protein 1 (UCP1), uncoupling protein 1 L homeolog (ucp1.L), uncoupling protein 1 (ucp1), uncoupling protein 1 (mitochondrial, proton carrier) (Ucp1), uncoupling protein 1 (Ucp1), AI385626, ARABIDOPSIS THALIANA PLANT UNCOUPLING MITOCHONDRIAL PROTEIN 1, ARABIDOPSIS THALIANA UNCOUPLING PROTEIN 1, ATPUMP1, ATUCP1, plant uncoupling mitochondrial protein 1, slc25a7, SLC25A7, Slc25a7, UCP, ucp, Ucp, UCP1, Ucpa, UNCOUPLING PROTEIN 1, UncpProtein level used designations for UCP1
- uncoupling protein 1 (mitochondrial, proton carrier)
- uncoupling protein 1
- mitochondrial brown fat uncoupling protein 1
- solute carrier family 25 member 7
- thermogenin
- UCP 1
- uncoupling protein 1 UCP1
- uncoupling protein 1, mitochondrial
- uncoupling protein, mitochondrial
- mitochondrial, proton carrier
- Solute carrier family 25 member 7
- Thermogenin
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