UCP3 Products
(Uncoupling Protein 3 (Mitochondrial, Proton Carrier) (UCP3))
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Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. The different UCPs have tissue-specific expression\; this gene is primarily expressed in skeletal muscle. This gene's protein product is postulated to protect mitochondria against lipid-induced oxidative stress. Expression levels of this gene increase when fatty acid supplies to mitochondria exceed their oxidation capacity and the protein enables the export of fatty acids from mitochondria. UCPs contain the three solcar protein domains typically found in MACPs. Two splice variants have been found for this gene.[provided by RefSeq, Nov 2008].
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Featured UCP3 Categories
UCP3 Antibodies
High quality antibodies with extensive validation data.
UCP3 ELISA Kits
Reliable ELISA kits for a wide range of species.
Recommended UCP3 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, IF
Validations
- (4)
Cat. No.
ABIN7159955
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, ICC, FACS
Validations
- (4)
Cat. No.
ABIN5542343
Quantity
0.1 mg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
IF
Validations
- (3)
Cat. No.
ABIN7259500
Quantity
200 μL
Datasheet
Datasheet
Recommended UCP3 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6971068
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6971069
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Validations
Cat. No.
ABIN435428
Quantity
96 tests
Datasheet
Datasheet
Recommended UCP3 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1324537
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3113994
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7505342
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our UCP3 products
: "Shc depletion stimulates brown fat activity in vivo and in vitro." in: Aging cell, Vol. 13, Issue 6, pp. 1049-58, (2014) (PubMed).: "Alterations in fatty acid utilization and an impaired antioxidant defense mechanism are early events in podocyte injury: a proteomic analysis." in: The American journal of pathology, Vol. 174, Issue 4, pp. 1191-202, (2009) (PubMed).
Synonyms and alternative names related to UCP3
uncoupling protein 3 (UCP3), uncoupling protein (UCP3), uncoupling protein (UCP1), uncoupling protein (UCP2), mitochondrial uncoupling protein 3 (LOC100303663), uncoupling protein 3 (mitochondrial, proton carrier) S homeolog (ucp3.S), mitochondrial uncoupling protein 3 (LOC100229080), uncoupling protein 3 (mitochondrial, proton carrier) (Ucp3), uncoupling protein 3 (Ucp3), AI645527, LOC100229080, slc25a9, SLC25A9, Slc25a9, UCP, UCP-3, UCP3Protein level used designations for UCP3
- mitochondrial carrier
- mitochondrial uncoupling protein
- mitochondrial uncoupling protein 3
- uncoupling protein
- uncoupling protein 3 (mitochondrial, proton carrier)
- uncoupling protein UCP
- mitochondrial uncoupling protein 3-like
- solute carrier family 25 member 9
- UCP 3
- uncoupling protein 3, mitochondrial
- Uncoupling protein 3, mitochondrial
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