This gene encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. Methylation of this gene is a potential marker for the presence of colorectal cancer. [provided by RefSeq, Jul 2008].
Merino, Singla: "Secreted Frizzled-Related Protein-2 Inhibits Doxorubicin-Induced Apoptosis Mediated through the Akt-mTOR Pathway in Soleus Muscle." in: Oxidative medicine and cellular longevity, Vol. 2018, pp. 6043064, (2018) (PubMed).
Aliases for SFRP2 Proteins
secreted frizzled-related protein 2 (sfrp2) Proteins secreted frizzled related protein 2 (SFRP2) Proteins secreted frizzled-related protein 2 S homeolog (sfrp2.S) Proteins secreted frizzled-related protein (sfrp2) Proteins sfrp2 (LOAG_01461) Proteins secreted frizzled-related protein 2 (Sfrp2) Proteins AI851596 Proteins frp-2 Proteins FRP-2 Proteins hm:zeh0225 Proteins sarp1 Proteins SARP1 Proteins sdf-5 Proteins SDF-5 Proteins Sdf5 Proteins sfrp-2 Proteins SFRP-2 Proteins SFRP2 Proteins sfrp2 Proteins zeh0225 Proteins zgc:153618 Proteins