SFRP2 Protein (AA 20-295) (His tag)
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- Target See all SFRP2 Proteins
- SFRP2 (Secreted Frizzled-Related Protein 2 (SFRP2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 20-295
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This SFRP2 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MGSSHHHHHH SSGLVPRGSH MGSARGLFLF GQPDFSYKRS NCKPIPVNLQ LCHGIEYQNM RLPNLLGHET MKEVLEQAGA WIPLVMKQCH PDTKKFLCSL FAPVCLDDLD ETIQPCHSLC VQVKDRCAPV MSAFGFPWPD MLECDRFPQD NDLCIPLASS DHLLPATEEA PKVCEACKNK NDDDNDIMET LCKNDFALKI KVKEITYINR DTKIILETKS KTIYKLNGVS ERDLKKSVLW LKDSLQCTCE EMNDINAPYL VMGQKQGGEL VITSVKRWQK GQREFKRISR SIRKLQC
- Purity
- > 85 % by SDS - PAGE
- Top Product
- Discover our top product SFRP2 Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
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Denatured
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Liquid. 20 mM Tris-HCl buffer ( pH 8.0) containing 10 % glycerol 0.4M urea
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- SFRP2 (Secreted Frizzled-Related Protein 2 (SFRP2))
- Alternative Name
- SFRP2 (SFRP2 Products)
- Synonyms
- frp-2 Protein, sarp1 Protein, sdf-5 Protein, sfrp-2 Protein, SFRP2 Protein, sfrp2 Protein, FRP-2 Protein, SARP1 Protein, SDF-5 Protein, AI851596 Protein, Sdf5 Protein, hm:zeh0225 Protein, zeh0225 Protein, zgc:153618 Protein, SFRP-2 Protein, secreted frizzled-related protein 2 Protein, secreted frizzled related protein 2 Protein, secreted frizzled-related protein 2 S homeolog Protein, secreted frizzled-related protein Protein, sfrp2 Protein, sfrp2 Protein, SFRP2 Protein, sfrp2.S Protein, LOAG_01461 Protein, Sfrp2 Protein
- Background
- SFRP2, as known as secreted frizzled-related protein 2, is a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. This protein acts as soluble modulators of Wnt signaling. Methylation of this gene is a potential marker for the presence of colorectal cancer. Recombinant human SFRP2 protein, fused to His-tag at N-terminus, was expressed in E.coli.
- Molecular Weight
- 33.8 kDa(297aa)
- NCBI Accession
- NP_003004
- UniProt
- Q96HF1
- Pathways
- WNT Signaling, Tube Formation, Positive Regulation of Endopeptidase Activity, Negative Regulation of intrinsic apoptotic Signaling, Positive Regulation of fat Cell Differentiation
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