anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B (ABCB1B) Antibodies

The membrane-associated protein encoded by ABCB1B is a member of the superfamily of ATP-binding cassette (ABC) transporters. Additionally we are shipping ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ABCB1B 5243 P08183
ABCB1B 18669 P06795
ABCB1B 24646  
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Top anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B Antibodies at antibodies-online.com

Showing 10 out of 31 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated FACS, IF (p), IHC (p) Formalin-fixed and paraffin embedded human lung carcinoma labeled with Anti-MDR1/p-GP/CD243 Polyclonal Antibody (ABIN670161), Unconjugated 1:200 at 1:200, followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded human lung carcinoma labeled with Anti-MDR1/p-GP/CD243 Polyclonal Antibody , Unconjugated 1:200 at 1:200, followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$318.45
Details
Human Rabbit Un-conjugated ICC, IF, IHC (p) Immunofluorescence analysis of mouse kidney tissue using anti-MDR1 (dilution of primary antibody - 1:1000) Immunohistochemical staining of paraffin embedded mouse kidney tissue using anti-MDR1 (primary antibody at 1:1000) 100 μg Log in to see 11 to 16 Days
$438.96
Details
Human Mouse Un-conjugated IF, IP, WB   100 μL Log in to see 16 Days
$405.08
Details
Human Mouse Un-conjugated IC, FACS, IHC, WB   250 μg Log in to see 11 to 16 Days
$771.57
Details
Human Rat Un-conjugated IC, FACS, IHC, WB   125 μg Log in to see 11 to 16 Days
$795.14
Details
Human Mouse Un-conjugated IC, FACS, IHC, WB   125 μg Log in to see 11 to 16 Days
$807.71
Details
Human Mouse Un-conjugated WB   100 μL Log in to see 11 to 16 Days
$570.43
Details
Human Mouse Un-conjugated IC, FACS, IP, IHC, WB   100 μg Log in to see 11 to 16 Days
$672.57
Details
Human Mouse Un-conjugated IC, FACS, IP   1 mL Log in to see 11 to 16 Days
$707.14
Details
Human Mouse Un-conjugated FACS, IF, IHC, WB   500 μL Log in to see 11 to 16 Days
$650.57
Details

ABCB1B Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B Antibodies

  1. Human Polyclonal ABCB1B Primary Antibody for FACS, IF (p) - ABIN670161 : Hu, Peng, Li: The expression and significance of P-glycoprotein, lung resistance protein and multidrug resistance-associated protein in gastric cancer. in Journal of experimental & clinical cancer research : CR 2009 (PubMed)
    Show all 2 Pubmed References

More Antibodies against ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B Interaction Partners

Human ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B (ABCB1B) interaction partners

  1. Results show that CD133 and MDR1 (show TBC1D9 Antibodies) expression increase in recurrent pediatric pilocytic astrocytomas (PAs (show PASK Antibodies)) following chemotherapy, and in drug resistant tumor cells. CD133 regulates MDR1 (show TBC1D9 Antibodies) expression via the PI3K (show PIK3CA Antibodies)/AKT (show AKT1 Antibodies)/NF-kappaB (show NFKB1 Antibodies) signaling. These results provide evidence that CD133 contributes to multidrug resistance by regulating MDR1 (show TBC1D9 Antibodies) levels via the PI3K (show PIK3CA Antibodies)-Akt (show AKT1 Antibodies)-NF-kappaB (show NFKB1 Antibodies) signal pathway.

  2. PG accumulation assay is a new, unique tool for the parallel determination of the function of the ABCG2 (show ABCG2 Antibodies), ABCB1 (show ABCB1 Antibodies), and ABCC1 (show ABCC1 Antibodies) multidrug transporters

  3. Abcb1a (show ABCB1 Antibodies)/b(-/-);Abcg2 (show ABCG2 Antibodies)(-/-) mice revealed increased brain penetration of rapamycin (13-fold), AZD8055 (7.7-fold), and NVP-BEZ235 (4.5-fold), but not ZSTK474 relative to WT mice. Importantly, ABC (show ABCB6 Antibodies) transporters limited rapamycin brain penetration to subtherapeutic levels, while the reduction in NVP-BEZ235 brain penetration did not prevent target inhibition.

  4. ABCB1 (show ABCB1 Antibodies) genotype is not a significant determinant of interindividual variability in dabigatran and rivaroxaban pharmacokinetics

  5. High MDR1 (show TBC1D9 Antibodies) expression is associated with multidrug resistance in breast cancer.

  6. inhibition of autophagy led to the decrease in stemness, restoration of mitochondrial proteins and reduced expression of CD44 (show CD44 Antibodies), ABCB1 (show ABCB1 Antibodies) and ADAM17 (show ADAM17 Antibodies)

  7. The T-allele of ABCB1 (show ABCB1 Antibodies)-C3435T gene polymorphism has demonstrated to be a good prognosis factor for resistance, progression free survival and overall survival in HER2 (show ERBB2 Antibodies)-positive Breast Cancer patients.

  8. we review the emerging role of molecular dynamics simulation techniques in our understanding of the membrane-embedded conformation of P-gp (show ABCB4 Antibodies)--{REVIEW}

  9. Studied ABCB1 (show ABCB1 Antibodies) protein expression immunohistochemically in twelve human post-mortem brain regions known to play a role in schizophrenia, in 13 patients with schizophrenia and nine controls; found a significantly reduced density of ABCB1 (show ABCB1 Antibodies)-expressing neurons in the left habenula.

  10. Using an integrated pathway-based approach, we identified polymorphisms in ABCC6 (show ABCC6 Antibodies), ABCB1 (show ABCB1 Antibodies) and CYP2C8 (show CYP2C8 Antibodies) associated with overall survival. These associations were replicated in a large independent cohort, highlighting the importance of pharmacokinetic genes as prognostic markers in Ewing sarcoma

Mouse (Murine) ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B (ABCB1B) interaction partners

  1. Molecular Dynamics simulations and docking of drugs performed for P-gp (P-gp (show ABCB4 Antibodies), multi-drug resistance protein, MDR1 (show ABCB4 Antibodies)).Drugs with ER < 1 (show MIER1 Antibodies) almost do not bind the main binding cavity (MBC (show CACNA1C Antibodies)) of P-gp (show ABCB4 Antibodies).

  2. conclusion, MDR1 (show ABCB4 Antibodies) and BCRP (show ABCG2 Antibodies) are expressed on apical membranes of the rodent placental SynT (show STX1A Antibodies)-II layer.

  3. Mdr1 (show ABCB4 Antibodies) enforces T Cell homeostasis in the presence of intestinal bile acids.

  4. Loss of ABCB1 (show ABCB1 Antibodies) expression is associated with neonatal hyperbilirubinemia.

  5. the high-affinity site of P-glycoprotein is inaccessible because of either a conformational change or binding of detergent at the binding site in a detergent micelle environment; ligands bind to a low-affinity site, resulting in altered modulation of P-gp (show ABCB4 Antibodies) ATPase (show DNAH8 Antibodies) activity

  6. Data suggest that ATP binding to Abcb1b/P-glycoprotein (Pgp) in liposomes exhibits cooperativity with verapamil (a cardiovascular/antiarrhythmia drug); cooperativity between verapamil and a nonhydrolyzable ATP analog (AMPPNP) leads to distinct global conformational changes in Abcb1b/Pgp.

  7. Chrysosplenetin inhibited P-gp (show ABCB4 Antibodies) activity and reverse the up-regulated P-gp (show ABCB4 Antibodies) and MDR1 (show ABCB4 Antibodies) levels induced by artemisinin.

  8. Tamsulosin and tolterodine with P-gp (show ABCB4 Antibodies) gene expression and activity in an enantiomer-specific way.

  9. Pgp (show ABCB4 Antibodies)-coupled ATPase (show DNAH8 Antibodies) activity kinetics measured with a range of verapamil and digoxin concentrations fit well to a DDI model encompassing non-competitive and competitive inhibition of digoxin by verapamil.

  10. Data show that human transgenic mutant huntingtin (show HTT Antibodies) (mHtt) aggregation might be regulated by multidrug resistance protein 1 (MDR1 (show ABCB4 Antibodies)) which suggests that MDR1 (show ABCB4 Antibodies) might be a potential therapeutic target for Huntington's disease.

ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B (ABCB1B) Antigen Profile

Protein Summary

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier.

Gene names and symbols associated with ABCB1B

  • ATP binding cassette subfamily B member 1 (ABCB1) antibody
  • ATP-binding cassette, sub-family B (MDR/TAP), member 1B (Abcb1b) antibody
  • ATP-binding cassette, subfamily B (MDR/TAP), member 1B (Abcb1b) antibody
  • ABC20 antibody
  • Abcb1 antibody
  • CD243 antibody
  • CLCS antibody
  • GP170 antibody
  • mdr antibody
  • Mdr1 antibody
  • Mdr1b antibody
  • P-GP antibody
  • Pgy-1 antibody
  • Pgy1 antibody

Protein level used designations for ABCB1B

P-glycoprotein 1 , colchicin sensitivity , doxorubicin resistance , multidrug resistance protein 1 , ATP-binding cassette sub-family B member 1 , P glycoprotein 1 , multidrug resistance protein 1B , ATP-binding cassette sub-family B (MDR/TAP) member 1 (P-glycoprotein/multidrug resistance 1) , ATP-binding cassette, sub-family B (MDR/TAP), member 1 (P-glycoprotein/multidrug resistance 1) , ATP-binding cassette, sub-family B (MDR/TAP), member 1B , ATP-binding cassette, subfamily B, member 1B , P-glycoprotein/multidrug resistance 1

GENE ID SPECIES
5243 Homo sapiens
18669 Mus musculus
24646 Rattus norvegicus
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