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anti-Activation-Induced Cytidine Deaminase (AICDA) Antibodies

AICDA encodes a RNA-editing deaminase that is a member of the cytidine deaminase family. Additionally we are shipping AICDA Proteins (8) and AICDA Kits (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
AICDA 57379 Q9GZX7
AICDA 11628 Q9WVE0
AICDA 399679  
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Top anti-AICDA Antibodies at antibodies-online.com

Showing 10 out of 121 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, IF, WB Immunocytochemistry of AID in Ramos cells with AP30028PU-N Ramos antibody at 10 μg/ml. Immunofluorescence of AID in Ramos cells with AP30028PU-N Ramos antibody at 20 μg/ml. 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Cow Goat Un-conjugated EIA, WB 20 μg Log in to see 6 to 8 Days
$203.50
Details
Human Goat Un-conjugated ELISA, WB ABIN263175 (0.1µg/ml) staining of Human Tonsil lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Rabbit FITC IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Un-conjugated ICC, IF, IHC (p), WB WB Image Sample (30 ug of whole cell lysate) A: NIH-3T3 10% SDS PAGE antibody diluted at 1:1000 WB Image Sample (30 ug of whole cell lysate) A: H1299 10% SDS PAGE antibody diluted at 1:1000 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Rabbit Un-conjugated ICC, IF, IHC (p), WB ICC/IF Image Immunofluorescence analysis of methanol-fixed HeLa, using AICDA, antibody at 1:500 dilution. IHC-P Image AICDA antibody [N1N2], N-term detects AICDA protein at cytosol on mouse lymph node by immunohistochemical analysis. Sample: Paraffin-embedded mouse lymph node. AICDA antibody [N1N2], N-term , dilution: 1:500. 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Rabbit Un-conjugated IF, IHC (p), WB 50 μg Log in to see 6 to 8 Days
$500.50
Details
Dog Rabbit Un-conjugated WB Western blot analysis of AID expression in HEK293T (A), PC12 (B) whole cell lysates. 200 μL Log in to see 9 Days
$487.50
Details
Human Rabbit Un-conjugated WB Western blot analysis of AID expression in MCF7 (A), NS-1 (B), PC12 (C) whole cell lysates. 200 μL Log in to see 9 Days
$487.50
Details
Human Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$433.13
Details

AICDA Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-AICDA Antibodies

  1. Human Polyclonal AICDA Primary Antibody for EIA, IF - ABIN499233 : Muramatsu, Sankaranand, Anant, Sugai, Kinoshita, Davidson, Honjo: Specific expression of activation-induced cytidine deaminase (AID), a novel member of the RNA-editing deaminase family in germinal center B cells. in The Journal of biological chemistry 1999 (PubMed)
    Show all 5 references for ABIN499233

  2. Human Polyclonal AICDA Primary Antibody for ELISA, WB - ABIN263175 : Crouch, Li, Takizawa, Fichtner-Feigl, Gourzi, Montaño, Feigenbaum, Wilson, Janz, Papavasiliou, Casellas: Regulation of AID expression in the immune response. in The Journal of experimental medicine 2007 (PubMed)

  3. Human Polyclonal AICDA Primary Antibody for IF (p) - ABIN881942 : Demberg, Mohanram, Musich, Brocca-Cofano, McKinnon, Venzon, Robert-Guroff: Loss of marginal zone B-cells in SHIVSF162P4 challenged rhesus macaques despite control of viremia to low or undetectable levels in chronic infection. in Virology 2015 (PubMed)

More Antibodies against AICDA Interaction Partners

Xenopus laevis Activation-Induced Cytidine Deaminase (AICDA) interaction partners

  1. Features of activation-induced deaminase (AID) mapping within the noncatalytic domain, but outside the chromosome region maintenance 1-dependent nuclear export signal at the C-terminus, influence its function.

Human Activation-Induced Cytidine Deaminase (AICDA) interaction partners

  1. AICDA/APOBEC family of cytidine deaminases is significant in innate immunity, as it restricts numerous viruses, including HBV, through hypermutationdependent and independent mechanisms. (Review)

  2. DNA methylation (show HELLS Antibodies) dynamics of germinal center B cells are mediated by AID.

  3. Mutations in activation-induced cytidine deaminase is associated with indolent chronic lymphocytic leukaemia.

  4. Data suggest novel mechanism in innate immunity allows cytokine TGF-beta (show TGFB1 Antibodies) to restrict viral circular DNA in hepatocyte nuclei via innate immunity; AID deaminates circular DNA of hepatitis B virus leading to DNA degradation; mechanism depends on UNG (show UNG Antibodies).

  5. The high levels of memory and activated B cells and follicular helper T cells were positively associated with the progression of immunoglobulin A nephropathy. This may be mediated by the overexpression of AID, which is potentially regulated by IL21 (show IL17C Antibodies).

  6. High expression of activation-induced cytidine deaminase is associated with diffuse large B cell lymphoma.

  7. AID mutations leading to AID deficiency are the most frequent underlying molecular basis of hyper IgM syndrome in consanguineous Tunisian patients.

  8. Studies indicate that gene conversion mediated by activation-induced cytidine deaminase (AID) has been found to contribute to generation of the primary antibody repertoire.

  9. aberrant expression of AID may reflect continuous B cell activation (show BLNK Antibodies) and sustained survival signals in HCV-related CV patients.

  10. Surges in ERK activity induced by extracellular cues enhance Arp2/3-mediated actin polymerization to generate protrusion power phases sufficient to promote sustained cell motility.

Mouse (Murine) Activation-Induced Cytidine Deaminase (AICDA) interaction partners

  1. Efficient chemoprotection of CDD (show CDA Antibodies) and MDR1 (show ABCB4 Antibodies) transduced hematopoietic 32D as well as primary lin(-) cells was proven in the context of Ara (show FOXC1 Antibodies)-C and anthracycline application

  2. Dendritic cells possess a mechanism to pass through micrometric constrictions. This mechanism is based on a rapid Arp2/3-dependent actin nucleation around the nucleus that disrupts the nuclear lamina, the main structure limiting nuclear deformability.

  3. DNA methylation (show HELLS Antibodies) dynamics of germinal center B cells are mediated by AID.

  4. demonstrate that the Arp2/3 complex in higher eukaryotes is actually a family of complexes with different properties

  5. The effect of insertion of transcribed intronic S regions in a locus (Igkappa)strongly recruiting AICDA on class switch recombination is reported.

  6. Platelet actin nodule formation is dependent on WASp (show WASL Antibodies) and the ARP2/3 complex.

  7. Study finds AID targets somatic hypermutation (SHM (show CNTNAP1 Antibodies)) hotspots within V exon and S region passengers at similar frequencies and that the normal SHM (show CNTNAP1 Antibodies) process frequently generates deletions, indicating that SHM (show CNTNAP1 Antibodies) and class-switch recombination employ the same mechanism.

  8. Splice variants of activation induced deaminase (AID) do not affect the efficiency of class switch recombination in murine CH12F3 cells

  9. AID deficiency inhibits DSA-mediated aortic vasculopathy after aorta transplantation in mice.

  10. HSP90 (show HSP90 Antibodies) inhibitors indirectly target AID in vivo

Cow (Bovine) Activation-Induced Cytidine Deaminase (AICDA) interaction partners

  1. crystal structure of Arp2 (show ACTR2 Antibodies)/3 complex

  2. These results demonstrate an important role for CRMP-1 (show CRMP1 Antibodies) in Listeria actin comet tail formation and open the possibility that CRMP-1 (show CRMP1 Antibodies) controls cell motility by modulating Arp2 (show ACTR2 Antibodies)/3 activation.

  3. TET3 (show TET3 Antibodies) dioxygenase was present in the very first embryo stages, in contrast to TET1 (show TET1 Antibodies) and AICDA.

  4. The GMF-Arp2 interface reveals how the ADF-H actin-binding domain in GMF is exploited to specifically recognize Arp2/3 complex and not actin.

  5. interacts with contactin and N-WASp (show WASL Antibodies)

  6. Data show that L. monocytogenes motility can be separated into an Arp2 (show ACTR2 Antibodies)/3-dependent nucleation phase, and an Arp2 (show ACTR2 Antibodies)/3-independent elongation phase which is dependent upon fascin (show FSCN1 Antibodies).

  7. crystal structures of Arp2/3 complex with bound ATP or ADP

  8. WASp stabilizes p35-dependent closure of the complex, holding Arp2 and Arp3 closer together to nucleate an actin filament.

  9. domain rearrangements of Arp2 and Arp3 result in a closed conformational state consistent with an "actin-dimer" model for the active state

  10. AICDA cDNA was cloned and expressed successfully in Escherichia coli generating a phenotype consistent with the mutating action of this deaminase. Using a whole genome radiation hybrid panel, AICDA was mapped to a region of chromosome 5.

Zebrafish Activation-Induced Cytidine Deaminase (AICDA) interaction partners

  1. there is currently no evidence to support the proposed roles of AID and MBD4 (show MBD4 Antibodies) in active demethylation in zebrafish embryos.

  2. Results provide evidence for a coupled mechanism of 5-methylcytosine (5-meC (show CCL28 Antibodies)) demethylation, whereby 5-meC (show CCL28 Antibodies) deaminase (AID)deaminates 5-meC (show CCL28 Antibodies), followed by thymine base excision by G:T mismatch-specific thymine glycosylase (Mbd4 (show MBD4 Antibodies)), promoted by Gadd45 (show GADD45A Antibodies).[AID]

  3. The promoters of both channel catfish (Ictalurus punctatus) and zebrafish (Danio rerio) Aicda genes were as transcriptionally active as an SV40 promoter control in all cell lines tested, regardless of the cells ability to express Aicda.

AICDA Antigen Profile

Protein Summary

This gene encodes a RNA-editing deaminase that is a member of the cytidine deaminase family. The protein is involved in somatic hypermutation, gene conversion, and class-switch recombination of immunoglobulin genes. Defects in this gene are the cause of autosomal recessive hyper-IgM immunodeficiency syndrome type 2 (HIGM2).

Gene names and symbols associated with AICDA

  • activation-induced cytidine deaminase (AICDA) antibody
  • activation-induced cytidine deaminase (aicda) antibody
  • activation-induced cytidine deaminase (aid) antibody
  • activation-induced cytidine deaminase (Aicda) antibody
  • ARP2 actin-related protein 2 (Actr2) antibody
  • ARP2 actin-related protein 2 homolog (yeast) (ACTR2) antibody
  • 4921510D23Rik antibody
  • AA409782 antibody
  • AICDA antibody
  • Aid antibody
  • Arp2 antibody
  • CDA2 antibody
  • D6Ertd746e antibody
  • HIGM2 antibody
  • xlaid antibody

Protein level used designations for AICDA

activation-induced cytidine deaminase , activation induced deaminase , activation-induced deaminase , cytidine aminohydrolase , integrated into Burkitt's lymphoma cell line Ramos , single-stranded DNA cytosine deaminase , activation induced cytidine deaminase , aid , ARP2 actin-related protein 2 homolog , actin-like protein 2 , actin-related protein 2

GENE ID SPECIES
418257 Gallus gallus
473404 Pan troglodytes
734224 Xenopus laevis
100008969 Oryctolagus cuniculus
100304619 Ictalurus punctatus
57379 Homo sapiens
11628 Mus musculus
539888 Bos taurus
442983 Canis lupus familiaris
399679 Rattus norvegicus
493784 Danio rerio
66713 Mus musculus
538486 Bos taurus
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