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Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein 1 Proteins (AIMP1)

The protein encoded by AIMP1 is a cytokine that is specifically induced by apoptosis, and it is involved in the control of angiogenesis, inflammation, and wound healing. Additionally we are shipping AIMP1 Antibodies (104) and AIMP1 Kits (15) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
AIMP1 9255 Q12904
Rat AIMP1 AIMP1 114632  
AIMP1 13722  
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Top AIMP1 Proteins at antibodies-online.com

Showing 10 out of 28 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 16 Days
$382.80
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 10 μg Log in to see 7 to 8 Days
$319.00
Details
HOST_Escherichia coli (E. coli) Mouse Un-conjugated 100 μg Log in to see 16 Days
$382.80
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   1 mg Log in to see 2 to 3 Days
$4,593.75
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Cricetulus griseus His tag   1 mg Log in to see 56 to 66 Days
$2,979.17
Details
HOST_Escherichia coli (E. coli) Human His tag   1 mg Log in to see 3 to 4 Days
$4,009.50
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 9 to 11 Days
$705.10
Details

AIMP1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

Top referenced AIMP1 Proteins

  1. Human AIMP1 Protein expressed in Escherichia coli (E. coli) - ABIN2003154 : Park, Jung, Lee, Jo, Motegi, Kim, Shiba: Precursor of pro-apoptotic cytokine modulates aminoacylation activity of tRNA synthetase. in The Journal of biological chemistry 1999 (PubMed)
    Show all 5 references for ABIN2003154

  2. Mouse (Murine) AIMP1 Protein expressed in Escherichia coli (E. coli) - ABIN2008178 : Shalak, Kaminska, Mitnacht-Kraus, Vandenabeele, Clauss, Mirande: The EMAPII cytokine is released from the mammalian multisynthetase complex after cleavage of its p43/proEMAPII component. in The Journal of biological chemistry 2001 (PubMed)
    Show all 5 references for ABIN2008178

  3. Human AIMP1 Protein expressed in Escherichia coli (E. coli) - ABIN667311 : Kim, Kim, Kim, Cho, Kim: AIMP1/p43 protein induces the maturation of bone marrow-derived dendritic cells with T helper type 1-polarizing ability. in Journal of immunology (Baltimore, Md. : 1950) 2008 (PubMed)
    Show all 2 references for ABIN667311

More Proteins for Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein 1 (AIMP1) Interaction Partners

Human Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein 1 (AIMP1) interaction partners

  1. AIMp1 promotes the proliferation and migration of fibroblasts/endothelial cells and importantly, pro-inflammatory gene expression in monocytes/macrophages and dendritic cells.

  2. AIMP1 appears to function as a novel inhibitor of PPARgamma (show PPARG Proteins) that regulates adipocyte differentiation by preventing the transcriptional activation of PPARgamma (show PPARG Proteins).

  3. Data indicate that HCV E2 glycoprotein interacts with cellular AIMP1/p43 protein and promotes cell surface expression of membrane glycoproteins gp96 (show HSP90B1 Proteins) and transforming growth factor beta TGF-beta signaling.

  4. Data indicate that the N terminus of Pro-EMAP II binds to its C terminus, arginyl-tRNA synthetase (show RARS Proteins), and the neurofilament light subunit.

  5. EMAP2 is a multifunctional polypeptide with proinflammatory and antiangiogenic activity. (Review)

  6. interactions between the N-terminal domains of ArgRS (show RARS Proteins) and AIMP1 are important for the catalytic and noncatalytic activities of ArgRS (show RARS Proteins) and for the assembly of the higher-order MSC (show MSC Proteins) protein complex with ArgRS (show RARS Proteins)-GlnRS (show QARS Proteins)-AIMP1

  7. AIMP1 peptide promotes the proliferation of BMMSCs by activating the beta-catenin (show CTNNB1 Proteins)/TCF (show HNF4A Proteins) complex via FGFR2 (show FGFR2 Proteins)-mediated activation of Akt (show AKT1 Proteins), which leads to an increase in mesenchymal stem cells in peripheral blood.

  8. Downregulation of CD23 (show FCER2 Proteins) attenuated AIMP1-induced TNF-alpha (show TNF Proteins) secretion and AIMP1 binding.

  9. we propose that AIMP1 effect on EC adhesion is mediated by the assembly of a cytoskeletal protein (show ACTN1 Proteins) complex on the cytosolic face of the cell membrane

  10. Decreased expression of AIMP1 in gastric and colorectal cancer tissues suggests that down-regulation of this protein may be related to inactivation of the tumor suppressor functions of AIMP proteins and might play a role in the development of GC and CRC (show CALR Proteins).

Mouse (Murine) Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein 1 (AIMP1) interaction partners

  1. findings indicate that Aimp1 might act as an important regulator to remodel the uterine endometrium and its expression might be regulated by estrogen during the estrous cycle.

  2. our results show that AIMP1 acts as a novel B cell-activating factor (show TNFSF13B Proteins)

  3. The data showed that AIMP1 is a negative regulator of TH2 immune responses, mainly via CD4 (show CD4 Proteins)+ T cells.

  4. In dendritic cells, AIMP1 enhances toll-like receptor 2 (TLR2)-mediated immune responses via the up-regulation of TLR2 expression.

  5. Lung-specific overexpression of EMAPII in mice caused simplification of alveolar structures, apoptosis, & macrophage accumulation. Smoking-induced upregulation involved an apoptosis-dependent feed-forward loop.

  6. AIMP1 plays a glucagon (show GCG Proteins)-like role in glucose homeostasis.

  7. Results suggest that AIMP1 acts as a regulator of the ER retention of gp96 (show HSP90B1 Proteins) and provide a new perspective of the regulatory mechanism underlying immune stimulation by gp96 (show HSP90B1 Proteins).

  8. AIMP1 induces the maturation and activation of dendritic cells, which skew the immune response toward a T helper type 1 (Th1 (show HAND1 Proteins)) cell response.

  9. AIMP1 negatively regulates TGF-beta (show TGFB1 Proteins) signaling via stabilization of Smurf2 (show SMURF2 Proteins).

  10. Mice lacking MSC (show MSC Proteins) p43 exhibited axon degeneration in motor neurons, defective neuromuscular junctions, muscular atrophy, and motor dysfunction. Furthermore, MSC (show MSC Proteins) p43 depletion in mice caused disorganization of the axonal neurofilament network.

Cow (Bovine) Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein 1 (AIMP1) interaction partners

  1. AIMP1 uses different regions for its diverse extracellular activities.

AIMP1 Protein Profile

Protein Summary

The protein encoded by this gene is a cytokine that is specifically induced by apoptosis, and it is involved in the control of angiogenesis, inflammation, and wound healing. The release of this cytokine renders the tumor-associated vasculature sensitive to tumor necrosis factor. The precursor protein is identical to the p43 subunit, which is associated with the multi-tRNA synthetase complex, and it modulates aminoacylation activity of tRNA synthetase in normal cells. This protein is also involved in the stimulation of inflammatory responses after proteolytic cleavage in tumor cells. Multiple transcript variants encoding different isoforms have been found for this gene. A pseudogene has been identified on chromosome 20.

Gene names and symbols associated with AIMP1

  • aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 (aimp1)
  • aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 (AIMP1)
  • aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 (Aimp1)
  • echinoderm microtubule associated protein like 2 (Eml2)
  • 1600029N02Rik protein
  • 9830137A06Rik protein
  • AIMP1 protein
  • AIMP1/p43 protein
  • Emap protein
  • Emap-2 protein
  • Emap2 protein
  • EMAPII protein
  • Eml1 protein
  • HLD3 protein
  • p43 protein
  • scye1 protein
  • wu:fa95a05 protein
  • zgc:154081 protein

Protein level used designations for AIMP1

aminoacyl tRNA synthase complex-interacting multifunctional protein 1 , aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 , small inducible cytokine subfamily E, member 1 (endothelial monocyte-activating) , ARS-interacting multifunctional protein 1 , endothelial monocyte-activating polypeptide 2 , endothelial-monocyte activating polypeptide II , multisynthase complex auxiliary component p43 , multisynthetase complex auxiliary component p43 , endothelial monocyte activating polypeptide 2 , small inducible cytokine subfamily E, member 1 , ARS inducible multifunctional protein 1 , EMAP-2 , echinoderm microtubule-associated protein-like 2

GENE ID SPECIES
562232 Danio rerio
695147 Macaca mulatta
100528334 Ictalurus punctatus
9255 Homo sapiens
114632 Rattus norvegicus
13722 Mus musculus
487893 Canis lupus familiaris
100135670 Sus scrofa
505126 Bos taurus
100009367 Oryctolagus cuniculus
379802 Xenopus laevis
72205 Mus musculus
192360 Rattus norvegicus
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