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anti-Amylo-alpha-1, 6-Glucosidase, 4-alpha-Glucanotransferase (AGL) Antibodies

AGL encodes the glycogen debrancher enzyme which is involved in glycogen degradation. Additionally we are shipping AGL Proteins (4) and AGL Kits (2) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
AGL 77559  
AGL 178 P35573
AGL 362029  
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Top anti-AGL Antibodies at antibodies-online.com

Showing 10 out of 43 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, IF, WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IF, WB Western blot using anti-AGL (C-term) antibody (ABIN389030) at 1:500 dilution. A total of 20 ug of lysates was loaded for each tissue. Data courtesy of Dr. Alan Cheng, Department of Internal Medicine, Life Sciences Institute, University of Michigan Medical Center, Ann Arbor, Michigan. Expression of myc-GS causes wild type but not the Ã�CBD mutant of AGL to aggregate around the PAS-stain-positive inclusions. HepG2 cells were transfected with either HA-tagged wild-type AGL (HA-AGL) or HA-AGL Ã�CBD. Cells were fixed in formalin and processed for IF using anti-HA (green) and anti-myc (red) antibodies. White arrows indicate colocalization of HA-AGL and myc-GS. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IF, WB Western blot analysis of hAGL-C371 (ABIN1882062) in K562 cell line lysates (35 µg/lane). AGL (arrow) was detected using the purified Pab. Western blot analysis of hAGL-C371 (ABIN1882062) in K562 cell line lysates (35 µg/lane). AGL (arrow) was detected using the purified Pab. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IP, WB (1) rat liver homogenate (50 µg of total protein), (2) GDE IP from 500 µg rat liver homogenate (3) GDE IP from 10 µg purified rat liver glycogen (see Parker et al, BBRC 2007) were resuspended into SDS PAGE sample buffer, boiled, electrophoresed on a pre-cast 4-15% gradient gel (Invitrogen, CA, USA) and transferred to PVDF membrane. Following blocking in 5% milk / PBST, membranes were probed with GDE antibodies (diluted 1/2000) for 1h at room temperature with rocking, followed by washing in 3 times for 5 min in PBS-T at room temperature with agitation. Blots were incubated in secondary antibody (Protein-G coupled to horse radish peroxidase conjugated – Bio-Rad) diluted 1:3000 for 1h at room temperature with agitation. The blots were washed as above and developed for 5 min with ECL (Invitrogen, CA, USA). Images were detected using the Fuji LAS-3000 system. To obtain GDE-bound immunoprecipitates, 5 µg GDE antibody was incubated with 500 µg rat liver homogenate or 10 ug purified rat liver glycogen together with 1 ml IP wash buffer (50 mM Hepes pH 7.5, 150 mM NaCl, 10% glycerol, 1% NP-40, 1 mM EGTA, 10 mM NaPPi and 100 mM NaF) and incubated at 4°C with mixing for 90 minutes. 100µ l, 20% Protein-A Sepharose was then added for a further 30 minutes at 4°C with mixing. Immunoprecipitates were collected by centrifugation at 7,000 rpm for 1 minutes and washed three times with IP wash buffer followed by resuspension into SDS PAGE sample buffer, boiling and electrophoresis as above. 200 μg Log in to see 5 to 6 Days
$497.81
Details
Human Rabbit Un-conjugated IF, WB 400 μL Log in to see 6 Days
$457.14
Details
Human Rabbit Alkaline Phosphatase (AP) ICC, ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Un-conjugated WB   100 μL Log in to see 8 to 10 Days
$383.17
Details
Human Rabbit Un-conjugated IF, ELISA   200 μL Log in to see 8 to 10 Days
$713.17
Details
Human Rabbit Un-conjugated ELISA   200 μL Log in to see 8 to 10 Days
$713.17
Details
Human Mouse Un-conjugated WB Western Blot analysis of AGL expression in transfected 293T cell line by AGL MaxPab polyclonal antibody.Lane 1: AGL transfected lysate(168.52 KDa).Lane 2: Non-transfected lysate. AGL MaxPab polyclonal antibody. Western Blot analysis of AGL expression in human liver. 50 μg Log in to see 9 Days
$430.00
Details

AGL Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine) ,


Human ,
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Rat (Rattus) ,


Top referenced anti-AGL Antibodies

  1. Human Polyclonal AGL Primary Antibody for IF, WB - ABIN1882062 : Hansen, Lundin, Markussen, Thorsby: T cell receptor usage by HLA-DQw8-specific T cell clones. in International immunology 1992 (PubMed)
    Show all 10 references for ABIN1882062

  2. Human Polyclonal AGL Primary Antibody for IF, WB - ABIN389030 : Parker, Kong, Walsh, Salajegheh, Moghadaszadeh, Amato, Nazareno, Lin, Krastins, Sarracino, Beggs, Pinkus, Greenberg: Fast-twitch sarcomeric and glycolytic enzyme protein loss in inclusion body myositis. in Muscle & nerve 2009 (PubMed)
    Show all 9 references for ABIN389030

  3. Human Polyclonal AGL Primary Antibody for IP, WB - ABIN343185 : Parker, Koay, Gilbert-Wilson, Waddington, Stapleton: AMP-activated protein kinase does not associate with glycogen alpha-particles from rat liver. in Biochemical and biophysical research communications 2007 (PubMed)
    Show all 3 references for ABIN343185

  4. Human Polyclonal AGL Primary Antibody for EIA, IF - ABIN357688 : Horinishi, Okubo, Tang, Hui, To, Mabuchi, Okada, Mabuchi, Murase: Mutational and haplotype analysis of AGL in patients with glycogen storage disease type III. in Journal of human genetics 2002 (PubMed)
    Show all 2 references for ABIN357688

More Antibodies against AGL Interaction Partners

Human Amylo-alpha-1, 6-Glucosidase, 4-alpha-Glucanotransferase (AGL) interaction partners

  1. AGL loss causes high SHMT2 (show SHMT2 Antibodies) expression and consequently increases glycine-dependent nucleotide synthesis leading to bladder cancer growth.

  2. Point mutations in AGL gene are associated with glycogen (show GYS1 Antibodies) storage disease type IIIa in a Chinese family.

  3. AGL haplotype analyses suggested that c.1019delA and c.958+1G>A are founder mutations in Turkish patients, while p.R864X is a recurrent mutation.

  4. A homozygous frameshift deletion, c.4456delT, in exon 33 of the AGL gene in Inuit children determines the cause of glycogen (show GYS1 Antibodies) storage disease type IIIa and confirms a founder effect.

  5. study identified 10 different mutations in 8 Korean Glycogen (show GYS1 Antibodies) storage disease type III patients; 5 mutations are novel and include 1 nonsense (c.1461G>A, p.W487X), 3 splicing (c.293+4_293+6delAGT in IVS4, c.460+1G>T in IVS5, c.2682-8A>G in IVS21) and 1 missense mutation (c.2591G>C, p.R864P)

  6. Characterization of a novel homozygous single point mutation at the polypyrimidine tract of intron 21 of the AGL gene in two consanguineous siblings with glycogen (show GYS1 Antibodies) storage disease type III.

  7. We found that most patients with macular telangiectasia-2 possess retinal autoantibodies, the most prevalent of which were directed against AGL, RBP3 (show E2F1 Antibodies), and CK-B.

  8. A founder effect discovered amongst Tunisian patients with glycogen (show GYS1 Antibodies) storage disease type III and a c.3216_3217delGA mutation in the AGL gene.

  9. Mutations in amylo-1,6-glucosidase is associated with Glycogen (show GYS1 Antibodies) Storage Disease Type III.

  10. The present patient was found to be deficient in GDE activity and homozygous for a novel 1 bp deletion in AGL. This mutation is predicted to cause premature termination at codon 834 due to frame shift.

AGL Antigen Profile

Protein Summary

This gene encodes the glycogen debrancher enzyme which is involved in glycogen degradation. This enzyme has two independent catalytic activities which occur at different sites on the protein: a 4-alpha-glucotransferase activity and a amylo-1,6-glucosidase activity. Mutations in this gene are associated with glycogen storage disease although a wide range of enzymatic and clinical variability occurs which may be due to tissue-specific alternative splicing. Alternatively spliced transcripts encoding different isoforms have been described.

Gene names and symbols associated with AGL

  • amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase (AGL) antibody
  • glycogen debranching enzyme (agl) antibody
  • glycogen debranching enzyme (Mmah_0764) antibody
  • amylo-1,6-glucosidase, 4-alpha-glucanotransferase (Agl) antibody
  • amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase (Agl) antibody
  • 1110061O17Rik antibody
  • 9430004C13Rik antibody
  • 9630046L06Rik antibody
  • AI850929 antibody
  • C77197 antibody
  • DDBDRAFT_0219237 antibody
  • DDBDRAFT_0234114 antibody
  • DDB_0219237 antibody
  • DDB_0234114 antibody
  • GDE antibody

Protein level used designations for AGL

amylo-1, 6-glucosidase, 4-alpha-glucanotransferase (glycogen debranching enzyme, glycogen storage disease type III) , glycogen debranching enzyme , amylo-1, 6-glucosidase, 4-alpha-glucanotransferase , amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase , glycogen storage disease type III , glycogen debrancher , amylo-1,6-glucosidase, 4-alpha-glucanotransferase , Glycogen debrancher

GENE ID SPECIES
469392 Pan troglodytes
517397 Bos taurus
8626162 Dictyostelium discoideum AX4
8982925 Methanohalophilus mahii DSM 5219
100126856 Sus scrofa
77559 Mus musculus
178 Homo sapiens
362029 Rattus norvegicus
479931 Canis lupus familiaris
100050695 Equus caballus
100009066 Oryctolagus cuniculus
Selected quality suppliers for anti-AGL (AGL) Antibodies
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