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The protein encoded by APOA5 is an apolipoprotein that plays an important role in regulating the plasma triglyceride levels, a major risk factor for coronary artery disease. Additionally we are shipping Apolipoprotein A-V Kits (45) and Apolipoprotein A-V Proteins (17) and many more products for this protein.
Showing 10 out of 152 products:
Chicken Polyclonal APOA5 Primary Antibody for EIA, WB - ABIN783518
Vu-Dac, Gervois, Jakel, Nowak, Bauge, Dehondt, Staels, Pennacchio, Rubin, Fruchart-Najib, Fruchart: Apolipoprotein A5, a crucial determinant of plasma triglyceride levels, is highly responsive to peroxisome proliferator-activated receptor alpha activators. in The Journal of biological chemistry 2003
Show all 2 references for ABIN783518
Human Monoclonal APOA5 Primary Antibody for ICC, ELISA - ABIN1724647
Pennacchio, Olivier, Hubacek, Cohen, Cox, Fruchart, Krauss, Rubin: An apolipoprotein influencing triglycerides in humans and mice revealed by comparative sequencing. in Science (New York, N.Y.) 2001
Show all 2 references for ABIN1724647
Human Polyclonal APOA5 Primary Antibody for EIA, WB - ABIN375169
Corella, Lai, Demissie, Cupples, Manning, Tucker, Ordovas: APOA5 gene variation modulates the effects of dietary fat intake on body mass index and obesity risk in the Framingham Heart Study. in Journal of molecular medicine (Berlin, Germany) 2007
Human Polyclonal APOA5 Primary Antibody for WB - ABIN530404
van den Berg, Heemskerk, Geerling, van Klinken, Schaap, Bijland, Berbée, van Harmelen, Pronk, Schreurs, Havekes, Rensen, van Dijk: Apolipoprotein A5 deficiency aggravates high-fat diet-induced obesity due to impaired central regulation of food intake. in FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2013
APOA5 rs2075291 could play an important role in triglyceride and HDL (show HSD11B1 Antibodies)-C level in metabolic syndrome, while the association of APOA5 rs662799 polymorphism is still under debate.
the TT genotype of APOA5 c.553G T may have an important role in Taiwanese patients with hypertriglyceridemia
APOA5 rs662799 polymorphism has interactions with the environmental factors associated with metabolic syndrome X.
APOA5 -1131 T > C and APOC3 (show APOC3 Antibodies) -455 T > C SNPs may play potent roles in the development and progression of coronary heart disease. (Meta-analysis)
Single nucleotide polymorphisms (Rs651821) of APOA5 protein did not increase the risk of CHD (show CHDH Antibodies) in the Chinese population.
Both the case-control study and meta-analysis confirm a significant association between APOA5 rs662799 and coronary heart disease. The results suggest a male-specific association between the APOA5 rs662799 polymorphism and coronary heart disease. [meta-analysis]
ApoA-V in neonates was unique in its serum concentration and in the association with lipoprotein profile
The polymorphisms rs662799 near APOA5 and rs769450 in APOE (show APOE Antibodies) had significant association with metabolic syndrome X and its components in Korean males.
Dietary fat intake modifies the effect of APOA5 and LEPR polymorphisms on serum triglycerides, cholesterol levels and obesity in young subjects.
No SNPs within the BUD13-APOA5 region were associated with effect on HDL (show HSD11B1 Antibodies)-cholesterol reduction but did have an effect on triglyceride and LDL-cholesterol levels following statin therapy.
novel role for ApoA5 as a modulator of susceptibility to diet-induced liver and muscle insulin (show INS Antibodies) resistance through regulation of ectopic lipid accumulation in liver and skeletal muscle.
The data suggest that apoA-V suppresses the production of chylomicrons, playing a previously unknown role in lipid metabolism that may contribute to the postprandial hypertriglyceridemia associated with apoA-V deficiency.
Data indicate that apolipoprotein A5 (APOA5) plays a role in the central regulation of food intake.
Clearance of triglyceride-rich lipoproteins by hepatic SDC1 (show SDC1 Antibodies) is atheroprotective and mediated by multivalent binding to ApoE (show APOE Antibodies) and ApoAV.
Gene transfer of human apoA-V improves the severe hypertriglyceridemia phenotype of apoa5 null mice.
Intravenously injected apoA-V rHDL significantly lowers plasma TG in an apoA-V deficient mouse model and requires gpihbp1 (show GPIHBP1 Antibodies).
Data show that livers from apolipoprotein A-V (APOA-V) transgenic mice contain significantly higher amounts of triglycerides than livers from wild-type or apoA-V knockout mice, suggesting that apoA-V influences intrahepatic triglyceride levels.
Preferential association of apoA-V(1-146) with murine plasma HDL (show HSD11B1 Antibodies), but not with VLDL, suggests that particle size is a determinant of its lipoprotein binding specificity.
a role of ApoA-V in regulating levels of circulating triglycerides and cholesterol.
Review. APOA5 represents a newly discovered gene involved in triglyceride metabolism in both humans and mice whose mechanism of action remains to be deciphered.
gene polymorphisms in APOA5 and APOC3 (show APOC3 Antibodies) are associated with meat quality traits in Kele pigs
The protein encoded by this gene is an apolipoprotein that plays an important role in regulating the plasma triglyceride levels, a major risk factor for coronary artery disease. It is a component of high density lipoprotein and is highly similar to a rat protein that is upregulated in response to liver injury. Mutations in this gene have been associated with hypertriglyceridemia and hyperlipoproteinemia type 5. This gene is located proximal to the apolipoprotein gene cluster on chromosome 11q23. Alternatively spliced transcript variants encoding the same protein have been identified.
, apolipoprotein AV
, apolipoprotein A5
, regeneration-associated protein 3