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anti-Arachidonate 15-Lipoxygenase B (ALOX15B) Antibodies

ALOX15B encodes a member of the lipoxygenase family of structurally related nonheme iron dioxygenases involved in the production of fatty acid hydroperoxides. Additionally we are shipping Arachidonate 15-Lipoxygenase B Kits (10) and Arachidonate 15-Lipoxygenase B Proteins (7) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ALOX15B 247 O15296
ALOX15B 266604 Q8K4F2
ALOX15B 11688 O35936
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Top anti-Arachidonate 15-Lipoxygenase B Antibodies at antibodies-online.com

Showing 10 out of 65 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-ALOX15B Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-ALOX15B Antibody Titration: 2.5ug/mlPositive Control: Jurkat cell lysate 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Formalin-fixed and paraffin-embedded human skin tissue reacted with PSMD13 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. Western blot analysis of ALOX15B Antibody (C-term) in CEM cell line lysates (35µg/lane). ALOX15B (arrow) was detected using the purified Pab. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-ALOX15B Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: HepG2 cell lysate WB Suggested Anti-ALOX15B  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500  Positive Control: HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 8 to 10 Days
$493.17
Details
Human Rabbit Un-conjugated IHC (p), WB Human Prostate (formalin-fixed, paraffin-embedded) stained with ALOX15B antibody ABIN214170 at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 8 to 10 Days
$595.83
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of ALOX15B Antibody (C-term) (ABIN653147) in CEM cell line lysates (35 µg/lane). ALOX15B (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human skin tissue reacted with PSMD13 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details

ALOX15B Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Arachidonate 15-Lipoxygenase B Antibodies

  1. Human Polyclonal ALOX15B Primary Antibody for EIA, IHC (p) - ABIN950355 : Wecksler, Kenyon, Garcia, Deschamps, van der Donk, Holman: Kinetic and structural investigations of the allosteric site in human epithelial 15-lipoxygenase-2. in Biochemistry 2009 (PubMed)
    Show all 2 references for ABIN950355

  2. Cow (Bovine) Polyclonal ALOX15B Primary Antibody for WB - ABIN2777052 : Soon, Libe, Benn, Gill, Shaw, Sywak, Groussin, Bertagna, Gicquel, Bertherat, McDonald, Sidhu, Robinson: Loss of heterozygosity of 17p13, with possible involvement of ACADVL and ALOX15B, in the pathogenesis of adrenocortical tumors. in Annals of surgery 2007 (PubMed)

  3. Cow (Bovine) Polyclonal ALOX15B Primary Antibody for WB - ABIN2777053 : Subbarayan, Xu, Kim, Yang, Hoque, Sabichi, Llansa, Mendoza, Logothetis, Newman, Lippman, Menter: Inverse relationship between 15-lipoxygenase-2 and PPAR-gamma gene expression in normal epithelia compared with tumor epithelia. in Neoplasia (New York, N.Y.) 2005 (PubMed)

More Antibodies against Arachidonate 15-Lipoxygenase B Interaction Partners

Human Arachidonate 15-Lipoxygenase B (ALOX15B) interaction partners

  1. The ALOX15B gene may be associated with coronary artery disease.

  2. ALOX15 (show ALOX15 Antibodies) rs11568070 polymorphisms did not discriminate for the disease or its severity.

  3. 15-LOX2 expression inhibits Myc (show MYC Antibodies)-induced prostate cancer development, such that in the 3-month- and 6-month-old double transgenic mice, there is a significant reduction in prostate intraneoplasia.

  4. activated ALOX15B in macrophages may play a role in the induction of atherothrombotic events by increasing platelet aggregation and thrombin (show F2 Antibodies) generation

  5. Positive feedback-loop of TERT (show TERT Antibodies) and 15-lipoxygenase-2 promotes pulmonary hypertension.

  6. Presented is the crystal structure of 15-LOX-2 in complex with an inhibitor that appears to bind as a substrate mimic. 15-LOX-2 contains a long loop, composed of hydrophobic amino acids, which projects from the amino-terminal membrane-binding domain.

  7. ALOX15B is the mainly expressed 12/15-lipoxygenase in human macrophages and that its expression is induced by IL-4 (show IL4 Antibodies), LPS (show IRF6 Antibodies) and hypoxia.

  8. Data indicate that expressions of 15-LO-1 and 15-LO-2 in placentas and umbilical artery (HUA) rings in preeclampsia (PE) increased more than that in normal groups.

  9. Tumor-associated macrophages isolated from RCC (show XRCC1 Antibodies) tumors had a high 15-LOX2 expression and secreted substantial amounts of 15(S)-hydroxyeicosatetraenoic acid.

  10. In summary, we observed associations between high ALOX15B expression in carotid lesions and a history of cerebrovascular symptoms.

Mouse (Murine) Arachidonate 15-Lipoxygenase B (ALOX15B) interaction partners

  1. Knockdown of mouse Alox15b in vivo decreased plaque lipid content and markers of inflammation.

  2. 15-LOX2 expression in mouse prostate leads to hyperplasia and also induces cell senescence.

  3. 8S-LOX plays a role as a prodifferentiating, antitumorigenic, and tumor suppressing gene in mouse skin carcinogenesis.

  4. Purified recombinant 8S-lipoxygenase can function as a potential 15-LOX (show ALOX15 Antibodies) by converting arachidonic acid exclusively to 8S-HPETE and then to (8S,15S)-dihydroperoxy-5Z,9E,11Z,13E-eicosatetraenoic acid (8S,15S-diHPETE).

  5. Expression of 8S-LOX and 15S-LOX-2 (show ALOX5 Antibodies) suppresses CRD-BP/IMP-1 (show IGF2BP1 Antibodies) expression, resulting in inhibition of human prostate carcinoma PC-3 (show PCSK1 Antibodies) cell proliferation.

Arachidonate 15-Lipoxygenase B (ALOX15B) Antigen Profile

Protein Summary

This gene encodes a member of the lipoxygenase family of structurally related nonheme iron dioxygenases involved in the production of fatty acid hydroperoxides. The encoded protein converts arachidonic acid exclusively to 15S-hydroperoxyeicosatetraenoic acid, while metabolizing linoleic acid less effectively. This gene is located in a cluster of related genes and a pseudogene that spans approximately 100 kilobases on the short arm of chromosome 17. Alternatively spliced transcript variants encoding different isoforms have been described.

Gene names and symbols associated with ALOX15B

  • arachidonate 15-lipoxygenase, type B (ALOX15B) antibody
  • arachidonate 15-lipoxygenase, type B (Alox15b) antibody
  • arachidonate 8-lipoxygenase (Alox8) antibody
  • 8-LOX antibody
  • 8S-LOX antibody
  • 15-LOX-2 antibody
  • 15-LOX-B antibody
  • Alox15b antibody

Protein level used designations for ALOX15B

arachidonate 15-lipoxygenase, type B , arachidonate 15-lipoxygenase, second type , 15-LOX-B , 15S-lipoxygenase , arachidonate 15-lipoxygenase 2 , arachidonate 15-lipoxygenase B , arachidonate 15-lipoxygenase type II , arachidonate omega(6) lipoxygenase , 15-LOX-2 , 15-lipoxygenase 2 , 8S-lipoxygenase

GENE ID SPECIES
716764 Macaca mulatta
100073039 Equus caballus
455104 Pan troglodytes
247 Homo sapiens
489485 Canis lupus familiaris
286820 Bos taurus
266604 Rattus norvegicus
100525835 Sus scrofa
11688 Mus musculus
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